Navigation Links
TheScientist Awards Seahorse XF96 Analyzer a Top Ten Innovation for 2009
Date:12/29/2009

NORTH BILLERICA, Mass., Dec. 29 /PRNewswire/ -- Seahorse Bioscience, Inc., leader in the design and development of instruments for measuring cellular bioenergetics, announced that TheScientist magazine cited their XF96 Extracellular Flux Analyzer as a 2009 Top Ten Innovation.

A panel of scientific experts assembled by TheScientist honored the XF Analyzer as the first instrument to measure the two energy pathways of the cell in a microplate, enabling scientists to generate a comprehensive picture of cellular bioenergetics in real-time. Cellular bioenergetics -the processes by which cells produce and consume energy - is fundamental to the growth, development, function and metabolism of cells. It has emerged as the hot new area of focus in the research of cancer; aging; and metabolic, cardiovascular, and neurodegenerative diseases.

"The XF Analyzers are revealing unexpected information about cellular respiration of cells that was not possible to attain before," noted John Lemasters, Director of the Center for Cell Death, Injury and Regeneration at the Medical University of South Carolina. "Insights from these findings are suggesting new strategies to rescue cells and tissues from irreversible toxic and ischemic injury."

The XF Analyzer is playing a key role in the resurgence of interest in the Warburg effect, an 80-year-old discovery about the way cancer cells prefer to burn sugar over fat. Blocking sugar metabolism can cause cancer cells to die, a phenomenon that is fueling a new wave of research into how cancers proliferate and ways to stop them.

"The XF Analyzer allows a scientist to see cancer cell metabolism in real time," stated Dr. Min Wu, Manager of Assay Development at Seahorse and author of several important cancer papers. "Studies utilizing the XF are revealing the metabolic dependencies of cancer cells on sugar and potential therapies. Scientists can determine whether a cancer is addicted to glucose (sugar) or glutamine, and establish which pathway to target for intervention."

Prior to the XF Extracellular Analyzer, scientists relied on 50 year old Clark electrode technology for measuring cell metabolism, a time-consuming technique that provides nominal basic information. Now in minutes, the XF Analyzer measures oxygen consumption--an indicator of mitochondrial respiration--as well as extracellular acidification, a product of glycolysis (sugar burning). With just a small number of cells, investigators can measure the effects of up to four compounds on cellular metabolism, determining the basal oxygen consumption and glycolysis rates; respiratory capacity; mitochondrial dysfunction; fatty acid oxidation, glucose, fatty acid, and amino acid metabolism; uncoupling; ATP turnover; and cell signaling in primary, adherent, tumor and suspension cells, islets, and isolated mitochondria. All important information needed when developing new drugs.

One of TheScientist's judge's Dr. H. Steven Wiley, summed up the XF Analyzer's significance stating: "I want one!'

About Seahorse Bioscience

SEAHORSE XF ANALYZERS have become the new standard in cellular bioenergetic measurements. Scientists worldwide use these tools to advance their research in understanding the role of mitochondrial function in obesity, diabetes, ageing, cancer, cardiovascular function and safety toxicity. Founded in 2001, Seahorse headquarters are in North Billerica, MA. For more information, please visit http://www.seahorsebio.com.


    Media Contact: Cynthia Egan
    Phone: 978.671.1610

SOURCE Seahorse Bioscience, Inc.


'/>"/>
SOURCE Seahorse Bioscience, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. U.S. Government Awards $15 Million Grant to GeoVax Labs HIV/AIDS Vaccine Program
2. CDC Awards NATT Funding to Improve Blood Clot Awareness
3. BoVir(R) Named Best New Veterinary Diagnostics Product in International Animal Pharm Awards
4. National Institutes of Health Awards $25.5M Contract to SRA
5. Provista Awards Agreement to Spheris
6. Schering-Plough Wins Three of Scrips Top Pharma Industry Awards
7. GBC Seeks Nominations for Regions Third Annual Bioscience Awards
8. The Michael J. Fox Foundation Awards $2 Million to Shed Light on Role of LRRK2 and Alpha-Synuclein Genes in Parkinsons Disease
9. Christopher and Dana Reeve Foundation Awards Nearly $2 Million in Individual Research Grants
10. New Enterprise Forum Celebrates 22nd Anniversary, Presents Annual Entrepreneur Awards to Randal Charlton & Others
11. CareEvolution and SCHIEx Named Interoperability Finalists for 2008 Microsoft Healthcare Users Group (MS-HUG) Healthcare Innovation Awards
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2016)... and LONDON , May 23, 2016 /PRNewswire/ ... See Frontage Boost Efficiency by 40% - Frontage Implement ... - Frontage Enforce Quality, Compliance and Traceability Within the Bioanalytical lab ... labs in the United States and ... to be deployed across its laboratory facilities. In addition to serving ...
(Date:5/20/2016)... (PRWEB) , ... May 20, 2016 , ... The leading ... of its most experienced veterinary clients have treated over 100 of their own patients ... technology to provide the highest level of care for their patients. , The ...
(Date:5/19/2016)... (PRWEB) , ... May 19, 2016 , ... Anton Paar ... 30,000 square foot office building is complete. The new structure adds a third office ... Anton Paar USA purchased 2.4 acres of land, along with office space ...
(Date:5/19/2016)... DIEGO , May 19, 2016 ... (OTC PINK: RGBP) and (OTC PINK: RGBPP) announced today ... creating the first cord blood based cancer immunotherapeutic ... provisional patent application, Regen described a generation of ... was potentiated by gene silencing.  The product in ...
Breaking Biology Technology:
(Date:4/19/2016)... , UAE, April 20, 2016 ... implemented as a compact web-based "all-in-one" system solution for ... biometric fingerprint reader or the door interface with integration ... modern access control systems. The minimal dimensions of the ... readers into the building installations offer considerable freedom of ...
(Date:4/14/2016)... , April 14, 2016 ... Malware Detection, today announced the appointment of Eyal ... new role. Goldwerger,s leadership appointment comes at ... heels of the deployment of its platform at several ... biometric technology, which discerns unique cognitive and physiological factors, ...
(Date:3/31/2016)... 31, 2016  Genomics firm Nabsys has completed a ... Barrett Bready , M.D., who returned to the company ... technical leadership team, including Chief Technology Officer, John ... Steve Nurnberg and Vice President of Software and Informatics, ... Dr. Bready served as CEO of Nabsys ...
Breaking Biology News(10 mins):