Navigation Links
The need to feed programs Campylobacter's 'Sat Nav'
Date:1/30/2013

A rumbling tummy is our body's way of telling us "it's time for lunch". Likewise, bacteria need to know when it's time to eat.

Researchers at the Institute of Food Research on the Norwich Research Park have uncovered how the food-borne bacterial pathogen Campylobacter jejuni can change its swimming behaviour to find a location with more food.

Campylobacter is the most common cause of bacterial food-borne illness in the UK, with more than 371,000 cases annually. When people get infected, the bacteria need to find their way from the source of contamination, most often undercooked poultry, to the cells lining the gut, passing through thick layers of mucus. In these different locations, Campylobacter must find enough food to sustain itself as well as a suitable environment to carry out respiration, the process of generating energy.

Using a newly developed assay, the researchers found that Campylobacter balances the directions given by two different systems to either seek out more nutritious locations, or to find places where respiration is most efficient. Genetic tools were used to show that the system controlling swimming towards food overrides the other system, suggesting that the "need to feed" is the foremost concern for Campylobacter.

Unlike other food poisoning bugs, such as E. coli or Salmonella, Campylobacter has a whole range of systems that can detect different chemicals in the environment, and alter swimming behaviour accordingly: the 'Sat Nav' of the bacterial world.

The work is published in the journal PLOS ONE. Dr Mark Reuter, the lead author says "we know that Campylobacter can swim, and that this is very important for causing disease, but aimless swimming isn't efficient. The bugs need to know where they want to go".

Discovering how these 'Sat Nav' systems help target the bugs to the site of infection may help prevent future disease, and may be relevant to other food-borne and gut-associated pathogens.


'/>"/>

Contact: Andrew Chapple
andrew.chapple@ifr.ac.uk
01-603-251-490
Norwich BioScience Institutes
Source:Eurekalert  

Related biology technology :

1. Wake Forest Innovations Partners with Veterinary Bioscience Institute to Develop Educational Programs for Life Science Professionals
2. NSBRI Renews Space Life Sciences Graduate Programs at MIT, Texas A&M
3. Novo Nordisk To Award $80,000 To Local Programs That Help People Living With Diabetes In Detroit As Part Of Educational Initiative
4. Big Pharma and Universities Increasingly Work to Advance Life Science Knowledge by Forming Strategic Partnerships, Public-Private Partnerships, and Open Innovation Programs: Pharmaceutical Research Collaborations Summit
5. Study Shows Transition to Practice Programs Get Nurses Employed
6. Intellect Neurosciences Adds Two New Tau Programs to its Alzheimers Disease Development Pipeline
7. FasterCures Spotlights Addario Lung Cancer Medical Institutes Innovative Research Programs
8. PAREXEL and ASAN Medical Center Establish Alliance to Accelerate Korea-based Drug Development and Commercialization Programs
9. CBI Announces 13th Annual Patient Assistance and Access Programs
10. Discovery Labs Reports Third Quarter Financial Results and Progress on Lead Programs
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
The need to feed programs Campylobacter's 'Sat Nav'
(Date:12/2/2016)... ... December 01, 2016 , ... ACEA Biosciences, Inc. announced ... I/II clinical trials for AC0010 at the World Conference on Lung Cancer 2016, taking ... update on the phase I/II clinical trials for AC0010 in patients with advanced non-small ...
(Date:12/2/2016)... ... December 01, 2016 , ... The Conference Forum has announced ... days and will take place on February 1-3, 2017 at the Roosevelt Hotel in ... (NCI), the program provides a unique 360-degree approach, which addresses the most up-to-date information ...
(Date:12/2/2016)... ... 2016 , ... Robots will storm the Prudential Center in Boston, MA during ... which is held on the United Nations International Day of Persons with Disabilities, will ... workplace. Suitable Technologies is partnering with NTI to showcase how technology can help individuals ...
(Date:11/30/2016)... ... November 30, 2016 , ... BEI Kimco, a brand of ... flexure design that ensures high alignment accuracy by preventing unwanted shaft rotation. The ... where extreme precision is required, such as in medical equipment, laboratory instrumentation, clean ...
Breaking Biology Technology:
(Date:11/29/2016)... CANNES, France , November 29, 2016 Nearly ... Continue Reading ... ... System is part of an efficient Identity Management. (PRNewsFoto/DERMALOG Identification Systems) ... DERMALOG is Germany's largest Multi-Biometric ...
(Date:11/21/2016)...   Neurotechnology , a provider of high-precision ... that the MegaMatcher On Card fingerprint matching algorithm ... NIST Minutiae Interoperability Exchange (MINEX) III ... of the evaluation protocol. The ... fingerprint templates used to establish compliance of template ...
(Date:11/15/2016)... , Nov. 15, 2016  Synthetic Biologics, ... developing therapeutics focused on the gut microbiome, today ... of 25,000,000 shares of its common stock and ... stock at a price to the public of ... to Synthetic Biologics from the offering, excluding the ...
Breaking Biology News(10 mins):