Navigation Links
The need to feed programs Campylobacter's 'Sat Nav'

A rumbling tummy is our body's way of telling us "it's time for lunch". Likewise, bacteria need to know when it's time to eat.

Researchers at the Institute of Food Research on the Norwich Research Park have uncovered how the food-borne bacterial pathogen Campylobacter jejuni can change its swimming behaviour to find a location with more food.

Campylobacter is the most common cause of bacterial food-borne illness in the UK, with more than 371,000 cases annually. When people get infected, the bacteria need to find their way from the source of contamination, most often undercooked poultry, to the cells lining the gut, passing through thick layers of mucus. In these different locations, Campylobacter must find enough food to sustain itself as well as a suitable environment to carry out respiration, the process of generating energy.

Using a newly developed assay, the researchers found that Campylobacter balances the directions given by two different systems to either seek out more nutritious locations, or to find places where respiration is most efficient. Genetic tools were used to show that the system controlling swimming towards food overrides the other system, suggesting that the "need to feed" is the foremost concern for Campylobacter.

Unlike other food poisoning bugs, such as E. coli or Salmonella, Campylobacter has a whole range of systems that can detect different chemicals in the environment, and alter swimming behaviour accordingly: the 'Sat Nav' of the bacterial world.

The work is published in the journal PLOS ONE. Dr Mark Reuter, the lead author says "we know that Campylobacter can swim, and that this is very important for causing disease, but aimless swimming isn't efficient. The bugs need to know where they want to go".

Discovering how these 'Sat Nav' systems help target the bugs to the site of infection may help prevent future disease, and may be relevant to other food-borne and gut-associated pathogens.


Contact: Andrew Chapple
Norwich BioScience Institutes

Related biology technology :

1. Wake Forest Innovations Partners with Veterinary Bioscience Institute to Develop Educational Programs for Life Science Professionals
2. NSBRI Renews Space Life Sciences Graduate Programs at MIT, Texas A&M
3. Novo Nordisk To Award $80,000 To Local Programs That Help People Living With Diabetes In Detroit As Part Of Educational Initiative
4. Big Pharma and Universities Increasingly Work to Advance Life Science Knowledge by Forming Strategic Partnerships, Public-Private Partnerships, and Open Innovation Programs: Pharmaceutical Research Collaborations Summit
5. Study Shows Transition to Practice Programs Get Nurses Employed
6. Intellect Neurosciences Adds Two New Tau Programs to its Alzheimers Disease Development Pipeline
7. FasterCures Spotlights Addario Lung Cancer Medical Institutes Innovative Research Programs
8. PAREXEL and ASAN Medical Center Establish Alliance to Accelerate Korea-based Drug Development and Commercialization Programs
9. CBI Announces 13th Annual Patient Assistance and Access Programs
10. Discovery Labs Reports Third Quarter Financial Results and Progress on Lead Programs
Post Your Comments:
Related Image:
The need to feed programs Campylobacter's 'Sat Nav'
(Date:10/12/2017)... ... 2017 , ... BioMedGPS announces expanded coverage of SmartTRAK Business ... US Hemostats & Sealants. , SmartTRAK’s US Market for Hemostats and Sealants module ... and biologic sealants used in surgical applications. BioMedGPS estimates the market will grow ...
(Date:10/11/2017)... ... ... eye wash is a basic first aid supply for any work environment, but most personal ... rinse first if a dangerous substance enters both eyes? It’s one less decision, and likely ... dual eye piece. , “Whether its dirt and debris, or an acid or alkali, getting ...
(Date:10/11/2017)... ... 11, 2017 , ... Disappearing forests and increased emissions are the main causes ... each year. Especially those living in larger cities are affected by air pollution related ... the most pollution-affected countries globally - decided to take action. , “I knew I ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... program has won a US2020 STEM Mentoring Award. Representatives of the FirstHand program ... in Volunteer Experience from US2020. , US2020’s mission is to change the trajectory ...
Breaking Biology Technology:
(Date:4/11/2017)... BROOKLYN, N.Y. , April 11, 2017 /PRNewswire-USNewswire/ ... identical fingerprints, but researchers at the New York ... University College of Engineering have found that partial ... fingerprint-based security systems used in mobile phones and ... previously thought. The vulnerability lies in ...
(Date:4/5/2017)... , April 5, 2017 Today HYPR ... that the server component of the HYPR platform is ... providing the end-to-end security architecture that empowers biometric authentication ... HYPR has already secured over 15 million users across ... manufacturers of connected home product suites and physical access ...
(Date:3/30/2017)... March 30, 2017  On April 6-7, 2017, ... Genome hackathon at Microsoft,s headquarters in ... will focus on developing health and wellness apps that ... Hack the Genome is the first hackathon for ... world,s largest companies in the genomics, tech and health ...
Breaking Biology News(10 mins):