Navigation Links
The butterfly effect in nanotech medical diagnostics
Date:2/6/2012

Tiny metallic nanoparticles that shimmer in the light like the scales on a butterfly's wing are set to become the color-change components of a revolutionary new approach to point-of-care medical diagnostics, according to a study published in International Journal of Design Engineering.

Thomas Schalkhammer and colleagues at Attophotonics Biosciences GmbH in Austria are working with Roland Palkovits of the University of Applied Sciences, in Wiener Neustadt, to develop a nanoparticle microfluidic color device for medical diagnostics. The team has demonstrated proof of principle in the detection of interleukin-6 as an important marker of acute sepsis.

The researchers point out that point-of-care medical diagnostics is an important part of healthcare today because it provides timely information to medical staff caring for patients as well as ensuring blood transfusion safety and providing useful surveillance data for emergency public health intervention as well as long-term public health strategies. Various studies, including one from the Bill and Melinda Gates Foundation and the National Institutes of Health (NIH) have emphasized repeatedly the importance of point-of-care diagnostics. As such, researchers the world over are searching for the insights and the technology to make simple, portable, and effective diagnostic devices to meet this need.

The Austrian team has developed a novel immunoassay for gold or palladium nanoparticles that are captured via immune-reactive proteins and positioned as a thin layer just a few nanometers above a light reflective surface. The nanoparticles and the mirror form an interference system the color of which can be tuned across the visible light spectrum. A microfluidic system - a so-called lab-on-a-chip - takes in a sample. If the target biomolecule, the disease marker, is present it will attach to the modified nanoparticles and cause a visible color change.

The addition of a silver colloidal solution enhances the effect making the metallic color change even more apparent. The tests can be performed in the clinic in just two to three minutes and importantly avoids any medical laboratory bottlenecks and incubation times for samples. The team reports that the tests are highly accurate and sensitive to a mere half a millionth of a milligram (500 picograms) per milliliter of sample. The nanoparticle test works even if the sample is cloudy.


'/>"/>

Contact: Thomas Schalkhammer
Schalkhammer@attophotonics.com
43-262-223-495
Inderscience Publishers
Source:Eurekalert

Related biology technology :

1. Nanometric butterfly wings created
2. A 50-year quest to isolate the thermoelectric effect is now over: Magnon drag unveiled
3. Breaking Study: ICU Medicals Tego® Needlefree Connector Proves More Cost Effective Than Traditional Central Venous Catheter Locks
4. Downsizing and the Need for Increased Selling Effectiveness Fuel Delta Points Growth
5. Penn and Brown researchers demonstrate earthquake friction effect at the nanoscale
6. Researchers shrink tumors and minimize side effects using tumor-homing peptide to deliver treatment
7. Internal and External Communications Excellence for the Pharmaceutical Industry: Increasing Organizational Effectiveness
8. Theravalues Confirms Beneficial Effects of Theracurmin™ on Diastolic Function in Hypertensive Patients
9. Bright Light into the Ear Canal Treats Seasonal Depression Effectively in Two Clinical Trials Presented by Valkee and University of Oulu
10. Study Shows C1-Esterase Inhibitor Concentrate is Safe and Consistently Effective for Long-Term Treatment of Hereditary Angioedema Attacks at Any Body Location
11. CBI Announces 3rd Effective Preparation for FDA Advisory Committees
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... Jolla, CA (PRWEB) , ... May 24, 2016 , ... ... financial planning for corporate executives and entrepreneurs, held The Future of San Diego Life ... in the San Diego life science community attended the event with speakers Dr. Rich ...
(Date:5/23/2016)... , May 23, 2016 Zimmer Biomet Holdings, ... healthcare, today announced that its Board of Directors has approved ... the second quarter of 2016. The cash ... about July 29, 2016 to stockholders of record as of ... of dividends are subject to approval of the Board of ...
(Date:5/23/2016)... ... May 23, 2016 , ... Foresight Institute , ... the winners for the 2015 Foresight Institute Feynman Prizes. , These prestigious ... categories, one for experiment and the other for theory in nanotechnology. Prof. Markus ...
(Date:5/20/2016)... ... May 20, 2016 , ... Korean researchers say Manumycin A triggers ... a new way to treat the disease. Surviving Mesothelioma has just posted an article ... from several Korean institutions based their mesothelioma study on the fact the Manumycin A, ...
Breaking Biology Technology:
(Date:3/14/2016)... Allemagne, March 14, 2016 ... - --> - Renvoi : image disponible ... --> --> DERMALOG, ... fournit de nouveaux lecteurs d,empreintes digitales pour l,enregistrement ... DERMALOG sera utilisé pour produire des cartes d,identité ...
(Date:3/10/2016)... Pa. , March 10, 2016   Unisys Corporation ... Customs and Border Protection (CBP) is testing its biometric ... San Diego to help identify certain non-U.S. ... . The test, designed to help determine the efficiency ... environment, began in February and will run until May 2016. ...
(Date:3/8/2016)... RALEIGH, N.C. , March 8, 2016 /PRNewswire/ ... biometric sensor technology, today announced it has secured ... led by GII Tech, a new venture fund ... LLC, with additional participation from existing investors TDF ... use the funds to continue its triple-digit growth ...
Breaking Biology News(10 mins):