Winston-Salem, NC (PRWEB) February 26, 2013
Dr. Szczepan Baran, president of the Veterinary Bioscience Institute (http://www.vetbiotech.com), is very pleased to announce his successful gastric bypass models in mice and rats; the workshops are now available to teach this procedure to qualified individuals.
Though research, development and careful manipulations, Dr. Baran has greatly improved the outcome in rodents undergoing gastric bypass surgeries. Dr. Baran’s post surgical survival rate is better than 99%.
Currently, the most effective therapy for the treatment of morbid obesity to induce significant and maintained body weight loss with a proven mortality benefit is bariatric surgery. Rats have always played a significant role as an animal model in obesity and diabetes studies. Recently, a Roux-en-Y gastric bypass rat surgery model has been developed as an obesity treatment model. However, studies have demonstrated that the Roux-en-Y gastric bypass surgical procedure not only leads to significant weight loss but it also leads to complete remission of Type 2 Diabetes Mellitus in 84% of patients. More interestingly, studies have demonstrated that the Type 2 Diabetes resolution occurs before the weight loss, suggesting that insulin sensitivity improves by a process that is independent of weight-loss. However the mechanism behind this remission is not well understood and the rat Roux-en-Y gastric bypass surgery model is being utilized to help understand this mechanism.
The rodent gastric bypass model is important as it closely mimics the weight loss experience in humans, and the model can be studied and manipulated in a controlled setting to infer results for other species. There are a wide variety of gastric bypass models available, and within each model, there are various standards for the surgical procedures. There are other signi
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