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The PROOF Centre of Excellence Partners with OriGene Technologies on Heart & Kidney Transplant Biomarker Program
Date:7/19/2012

ROCKVILLE, Md., July 19, 2012 /PRNewswire/ -- OriGene Technologies, Inc. and Canada's Centre of Excellence for the Prevention of Organ Failure (PROOF Centre) today announced the selection of OriGene Technologies as a major collaboration and development partner to implement blood-based protein assays in heart and kidney transplantation. This multi-year, collaborative project funded by multiple partners will provide monitoring and predictive blood tests, based upon OriGene's extensive expertise in immunoassay and antibody development, to improve the care of heart and kidney transplant patients worldwide.

OriGene Technologies, as a leading assay development partner for the project, will leverage its industry leading collection of gene-centric tools, high quality monoclonal antibody validation technologies, and expertise in Luminex® multiplex assay development to create diagnostic assays for the clinical transplantation environment and integrate these novel tools to improve patient care. This is the first announced clinical development project that will utilize OriGene's highly validated and "mono-specific" antibodies known as UltraMAB™ Antibodies. UltraMAb antibodies are a newly released class of antibody products validated for specificity and low cross-reactivity, thus reducing potential side effects or false diagnostic reports in clinical studies.

According to a recently completed economic evaluation prepared by the PROOF Centre, the reduction in the costs from implementing blood based tests in organ rejection could result in savings of $700,000 over 5 years for the heart and kidney transplant programs in British Columbia. Furthermore, implementation of such tests would dramatically improve the quality of life for heart and kidney transplant patients and reduce the need for costly biopsies, which have no predictive value in measuring acute graft rejection, one of the most important causes of early morbidity and graft injury in organ
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SOURCE OriGene Technologies, Inc.
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