Navigation Links
The National Center for Genome Resources Studies Childhood Diseases Using febit's DNA Capture Method
Date:8/10/2009

LEXINGTON, Mass. and HEIDELBERG, Germany, Aug. 10 /PRNewswire/ -- The National Center for Genome Resources (NCGR) has selected febit's DNA-capture method, HybSelect(TM), to re-sequence the exons of genes involved in over 400 of the most devastating childhood diseases with the ultimate goal of developing genetic tests to detect carrier status for recessive genetic diseases in prospective parents.

In this collaboration the NCGR will bring its experience in comprehensive Illumina sequencing studies to febit's automated HybSelect technology for targeted re-sequencing to develop and test highly parallel analysis. This will enhance the multiplexing capability of HybSelect to perform surveys in large-cohort studies.

NCGR scientists searched for a fast and affordable technology that would allow them to capture the exons of interest for re-sequencing. febit's automated HybSelect technology for targeted, hybridization-based DNA enrichment supports deep sequencing studies resulting in high coverage results. The Geniom RT Analyzer provides the easy-to-use and highly automated capturing of the desired DNA fragments for further Next-Generation Sequencing (NGS).

Stephen Kingsmore, CEO of NCGR, stated: "We are impressed by the unique flexibility and scalability of febit's HybSelect technology and with the ease of integration in production sequencing with Illumina Genome Analyzers. In partnership with the Beyond Batten Disease Foundation, we aim to combine these technologies to offer highly cost effective screening for rare childhood diseases."

febit will provide its technology, application, training and support to NCGR. "We are delighted that NCGR will use our flexible Geniom technology to investigate rare genomic diseases," said Peer Staehler, CSO of febit. "The flexible content of the microarray-based biochip allows researchers to fully determine the capture probes and incorporate new results. This cooperation supports febit's progress in developing capable new biomarkers for complex diseases."

About NCGR

NCGR is a non-profit research institute, based in Santa Fe, New Mexico, dedicated to improving human health and nutrition by genome sequencing and analysis.

For more information, please visit www.ncgr.org.

About the Beyond Batten Disease Foundation

BBDF is an organization committed to finding a cure for Batten disease, a rare and fatal neurodegenerative disorder that claims the lives of children. The Foundation is also focused on developing a single, inexpensive blood test to detect the gene mutations for Batten disease and hundreds of rare genetic diseases.

For more information, please visit www.beyondbatten.org.

About febit

febit develops, produces and markets flexible automated solutions for enabling biochip applications in Life Sciences. febit's product portfolio includes various instruments, optimized assays and bioanalytical services, complemented by bioinformatics software and consulting.

For its main applications -- HybSelect, febit's innovative DNA capture method for Next-Generation-Sequencing and protein-coding or non-coding transcriptome profiling -- the highly advanced microfluidics of the patented Geniom Biochip offers the highest degree of automation, flexibility and efficiency available.

For more information, please visit www.febit.com.

    Contact:
    febit group, Eva Sterzel, eva.sterzel@febit.com, +49 (0)6221 6510-300

    Russo Partners, Martina Schwarzkopf,
    martina.schwarzkopf@russopartnersllc.com, +1 212 845-4292


'/>"/>
SOURCE febit
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. Microfluidics International Corporation to Report Second Quarter 2009 Financial Results on August 11, 2009
2. The Foundation for National Institutes of Health Announces Unprecedented Product Donation by sanofi-aventis in the U.S.
3. Patent Attorney John Rizvi Speaks at FIME International Medical Expo
4. Zeus Expands International Support With New Hires
5. National Institutes of Health Chooses Web of Science(R) to Power electronic Scientific Portfolio Assistant (eSPA)
6. International Milk Genomics & Human Health Symposium Speaker Program Announced
7. Yongye International Announces Branded Store Network Increases Over 40% to 5,000 Stores
8. U.S. Federal Trade Commission to Challenge Thoratecs Proposed Acquisition of HeartWare International
9. Peregrine Pharmaceuticals to Present at the Jesup & Lamont 2009 Growth Stock & National Sales Conference
10. Thomson Reuters Announces 2009 Edition of the CMR International Pharmaceutical R&D Factbook
11. Junying Yu, Leading Stem Cell Researcher, Joins Cellular Dynamics International
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/2/2016)... , May 2, 2016 Q ... its technology partner Mannin Research Inc. will be attending ... which takes place from May 1-5, 2016 in ... be meeting with its vendors and research partners. The ... development goals and other collaborative opportunities for the MAN-01 ...
(Date:4/29/2016)... (PRWEB) , ... April 30, 2016 , ... The MIT ... textile design, the bioLogic team explored how bacterial properties can be applied to fabric ... using Natto bacteria, which move in response to humidity change. The team harvested Natto ...
(Date:4/29/2016)... ... 2016 , ... During a two day program for start-up ... CereScan’s CEO, John Kelley, joined other Denver business leaders in providing business basics ... Denver area business community, shared his top fundamental learnings in building an effective, ...
(Date:4/28/2016)... The report "Cryocooler Market by ... (Technical Support, Product Repairs & Refurbishment, Preventive Maintenance, and ... 2022", published by MarketsandMarkets, the global market is expected ... a CAGR of 7.29% between 2016 and 2022. ... Figures spread through 159 Pages and in-depth TOC on ...
Breaking Biology Technology:
(Date:3/11/2016)... http://www.apimages.com ) - --> http://www.apimages.com ) - ... Images ( http://www.apimages.com ) - Germany . ... new refugee identity cards. DERMALOG will be unveiling this device, and ... Hanover next week.   --> Germany ... the new refugee identity cards. DERMALOG will be unveiling this device, ...
(Date:3/9/2016)... -- This BCC Research report provides an overview of ... (RNA Seq) market for the years 2015, 2016 and ... data analysis, and services. Use this report ... such as RNA-Sequencing tools and reagents, RNA-Sequencing data analysis, ... segment and forecast their market growth, future trends and ...
(Date:3/3/2016)...  FlexTech, a SEMI Strategic Association Partner, awarded five ... Development, Leadership in Education, and, in a category new ... year of the FLEXI Awards and the winners ... past years . Judging was done on a ... criteria, by a panel of non-affiliated, independent, industry experts. ...
Breaking Biology News(10 mins):