Navigation Links
The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline
Date:10/7/2008

ogether microbiologists, molecular biologists, synthetic chemists, medicinal chemists, pharmacologists, toxicologists, and process chemists to expedite the testing and optimizing of early-stage compounds to fill the pipeline for drug development.

"This Initiative is founded on the belief that people from different corners of the pharmaceutical and healthcare world will put aside differences and come together when confronted with a global threat," said Dr. Gail Cassell, Lilly's vice president of scientific affairs and distinguished research scholar. "Our collaboration around these two compounds proves that this belief is true. We are encouraged by the response and inspired by the commitment of our colleagues."

Over the past year, The Lilly TB Drug Discovery Initiative has organized operations and labs and identified compounds for the first round of work. Within the next few months, it plans to begin high-throughput screening of new, validated targets against well-characterized chemical libraries.

In addition to screening activities, the Initiative will study the potential of the newly acquired compounds from MCRF and Summit plc:

-- MCRF has discovered CPZEN-45, an early stage clinical candidate which may have a new mechanism of action against TB, and also shows efficacy against multidrug-resistant and extensively drug resistant TB infected mice without any detectable side effect so far examined.

-- Summit plc's compounds also show significant potential as a new class of antibiotics for treatment of TB and will be further explored by the Initiative.

Organizations co-developing compounds with the Initiative or contributing research tools will have the opportunity to request access to NIH-sponsored resources and receive valuable data to assist the Initiative's research process.

More than 1.5 million people die each year from TB, most of them in low income countries. However, TB is spreading globally and evolving rapidly i
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Lilly to Acquire ImClone Systems in $6.5 Billion Transaction
2. Covance and Lilly Finalize 10-Year, $1.6 Billion Strategic R&D Collaboration
3. BioMS Medical announces receipt of milestone payment from Eli Lilly and Company
4. Amylin Pharmaceuticals and Eli Lilly Provide Context for FDA Alert for BYETTA
5. Amylin and Lilly Set Date and Time for Conference Call
6. Lilly Announces Completion of SGX Acquisition
7. SGX - Lilly Merger Offer Receives Positive Opinions From Proxy Advisory Firms
8. Lilly Reaffirms Purchase Offer for SGX Pharmaceuticals
9. Lilly Reports Solid Second-Quarter Results
10. Lilly to Acquire SGX Pharmaceuticals
11. Lillys Connelly Appointed to the Presidents Commission on White House Fellowships
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Biotechnology Company, Limited ("TaiGen") today announced that they have ... pharmaceutical company, to develop and commercialize nemonoxacin (Taigexyn ® ... Turkey and other members of ... for the treatment of bacterial infections including those caused ...
(Date:1/14/2014)... Carahsoft and CDS Federal Services have ... at 2pm EST (11am PST), “Natural Language Processing: Converting ... how technology can turn raw, heterogeneous data into actionable ... The online webinar will last approximately one hour. , ...
(Date:1/14/2014)... Jan. 14, 2014  3D Communications, a leading provider of strategic communications ... and media events in the United States ... Virginia Cox , JD, is returning to the firm,s ... re-joins 3D after more than two years of service as ...
(Date:1/14/2014)... NY (PRWEB) January 14, 2014 EquitiesIQ, ... Alliqua, Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical ... serve the wound care market. , Free report download: ... restructured with a seasoned management team and Board, which ...
Breaking Biology Technology:TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2Former FDA Associate Commissioner Returns To 3D Communications 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3
... REDWOOD CITY, Calif., March 4 Maxygen, Inc.,(Nasdaq: ... the development of,improved protein drugs, today announced changes ... president in charge of global,business development and U.S. ... business officer. In addition, the company announced the,pending ...
... new independent non-executive directors added to Board with ... ... appointed independent non-executive Chairman, BRISBANE, Australia, March 4 ... John Lee and Robert Williamson to the Company,s Board as,independent ...
... Biosciences,(Nasdaq: MATK ) announced today that life,sDHA, its ... heart health, is available in new So,Good Omega DHA ... selling soymilk brand. Available in original or vanilla flavor, ... major retailers throughout,Canada., "So Good Omega DHA Soymilk ...
Cached Biology Technology:Maxygen Announces Management Changes 2Progen Expands Board of Directors 2Progen Expands Board of Directors 3Progen Expands Board of Directors 4Canada's Best-Selling Soymilk Now Available with Martek's life'sDHA 2Canada's Best-Selling Soymilk Now Available with Martek's life'sDHA 3
(Date:4/23/2014)... conclusive evidence that the source of a unique rhythmic ... called the "bio-duck," is the Antarctic minke whale ( ... personnel in the 1960s who thought it sounded like ... various locations in the Southern Ocean, but its source ... 2013, an international team of researchers deployed acoustic tags ...
(Date:4/23/2014)... the likelihood of an accurate group decision increases with ... when a collective faces a variety of factors ... University researchers report that smaller groups actually tend to ... excessively focused on only certain pieces of information. , ... known about collective intelligence, or the "wisdom of crowds," ...
(Date:4/23/2014)... The shale gas boom has transformed the energy ... locations, it could cause conflict among the energy ... resources, say researchers. They add that degraded water ... adequate safeguards. The feature article appears in the ... , Meagan S. Mauter and colleagues point out ...
Breaking Biology News(10 mins):Scientists identify source of mysterious sound in the Southern Ocean 2Scientists identify source of mysterious sound in the Southern Ocean 3Too many chefs: Smaller groups exhibit more accurate decision-making 2Too many chefs: Smaller groups exhibit more accurate decision-making 3How to avoid water wars between 'fracking' industry and residents 2
... January 11, 2010 Why do some people like to ... hand, taking the opposite tack by buying insurance to reduce ... Hebrew University of Jerusalem and two Asian universities say the ... team set out to tackle the long-standing question in economic ...
... standards to help ensure the quality and enhance the ... and a variety of functional foods are being proposed ... internationally recognized compendium of quality standards for food ingredients. ... breast milk and commonly added to infant formula, and ...
... Ohio Blocking the function of an enzyme in the ... nerve cells from dying after a stroke, new research suggests. ... that the tocotrienol form of vitamin E, an alternative to ... acids that eventually kill neurons. The Ohio State University ...
Cached Biology News:Why do people 'play the longshot' and buy insurance? It's in our genes 2Quality and safety of infant formulas, functional foods enhanced by new standards 2Quality and safety of infant formulas, functional foods enhanced by new standards 3Study reveals how one form of natural vitamin E protects brain after stroke 2Study reveals how one form of natural vitamin E protects brain after stroke 3
... ProFound Label Transfer Sulfo SBED Protein:Protein ... known as Label Transfer has rapidly gained ... protein interaction discovery. A growing number of ... Biotin Label Transfer Reagent to study a ...
... compact benchtop and stackable multi-function incubator. ... a large display screen to accurately ... circulation inside to evenly distribute temperature ... easily calibrated from the microprocessor controller. ...
... emerging as a powerful new tool for ... only amino groups have been able to ... as our Sulfo-SBED. Sulfhydryl-reactive Mts-Atf-Biotin and its ... to the protein interaction tool chest that ...
... designed as a high tech shaker for ... compensation allows high shaking speed even under ... therefore, faster growth and higher cell density. ... high reproducibility is critical Variable ...
Biology Products: