Navigation Links
The Lilly TB Drug Discovery Initiative Begins Work on New Compounds to Fill Early-Stage TB Drug Pipeline
Date:10/7/2008

ogether microbiologists, molecular biologists, synthetic chemists, medicinal chemists, pharmacologists, toxicologists, and process chemists to expedite the testing and optimizing of early-stage compounds to fill the pipeline for drug development.

"This Initiative is founded on the belief that people from different corners of the pharmaceutical and healthcare world will put aside differences and come together when confronted with a global threat," said Dr. Gail Cassell, Lilly's vice president of scientific affairs and distinguished research scholar. "Our collaboration around these two compounds proves that this belief is true. We are encouraged by the response and inspired by the commitment of our colleagues."

Over the past year, The Lilly TB Drug Discovery Initiative has organized operations and labs and identified compounds for the first round of work. Within the next few months, it plans to begin high-throughput screening of new, validated targets against well-characterized chemical libraries.

In addition to screening activities, the Initiative will study the potential of the newly acquired compounds from MCRF and Summit plc:

-- MCRF has discovered CPZEN-45, an early stage clinical candidate which may have a new mechanism of action against TB, and also shows efficacy against multidrug-resistant and extensively drug resistant TB infected mice without any detectable side effect so far examined.

-- Summit plc's compounds also show significant potential as a new class of antibiotics for treatment of TB and will be further explored by the Initiative.

Organizations co-developing compounds with the Initiative or contributing research tools will have the opportunity to request access to NIH-sponsored resources and receive valuable data to assist the Initiative's research process.

More than 1.5 million people die each year from TB, most of them in low income countries. However, TB is spreading globally and evolving rapidly i
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related biology technology :

1. Lilly to Acquire ImClone Systems in $6.5 Billion Transaction
2. Covance and Lilly Finalize 10-Year, $1.6 Billion Strategic R&D Collaboration
3. BioMS Medical announces receipt of milestone payment from Eli Lilly and Company
4. Amylin Pharmaceuticals and Eli Lilly Provide Context for FDA Alert for BYETTA
5. Amylin and Lilly Set Date and Time for Conference Call
6. Lilly Announces Completion of SGX Acquisition
7. SGX - Lilly Merger Offer Receives Positive Opinions From Proxy Advisory Firms
8. Lilly Reaffirms Purchase Offer for SGX Pharmaceuticals
9. Lilly Reports Solid Second-Quarter Results
10. Lilly to Acquire SGX Pharmaceuticals
11. Lillys Connelly Appointed to the Presidents Commission on White House Fellowships
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... California (PRWEB) January 22, 2015 Pipette.com ... Offer to their comprehensive portfolio of Eppendorf products. ... customers to purchase a Centrifuge 5424/5424 R and receive ... of either Eppendorf Research plus or Eppendorf Reference 2 ...
(Date:1/22/2015)... Selexis SA, a serial innovation company with ... used for drug discovery to commercial manufacturing, announced today ... Next-Generation Sequencing (NGS) data packages. The NGS analysis ... ensuring the integrity of the gene, validation of the ...
(Date:1/22/2015)... Medical Systems (NYSE: VAR ), world leader in ... to sustainability with inclusion on a prestigious list of the ... equipment company among the Corporate Knights Global 100 Most Sustainable ... Davos, Switzerland . "We ...
(Date:12/24/2014)... , Dec. 24, 2014  United Therapeutics Corporation (NASDAQ: ... (NYSE: MDT ) has submitted a pre-market ... (FDA) for the use of Medtronic,s SynchroMed ® ... catheter) for use with United Therapeutics, Remodulin ® ...
Breaking Biology Technology:Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2Selexis Generated Research Cell Banks Now Fully Sequenced Using Next-Generation Sequencing 2Varian Honored Among World's 100 Most Sustainable Corporations 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 2United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 3United Therapeutics Announces Submission Of Pre-Market Approval Application For Implantable Drug Infusion System To Deliver Remodulin 4
... SOUTH SAN FRANCISCO, Calif., Oct. 17 Poniard,Pharmaceuticals, ... focused,on oncology, today announced that its lead product ... for the treatment of,small cell lung cancer (SCLC) ... a recommendation from the Committee for Orphan Medicinal,Products ...
... Penn., Oct. 17 Respironics, Inc.,(Nasdaq: RESP ... market,announced today that it intends to release its ... 2007 on Thursday October 25, 2007. In,conjunction with ... and,business outlook, Respironics will host a conference call ...
... unique resources to empower transplant patients ... ... Astellas Pharma US,Inc. (Pink Sheets: ALPMF), a leader in the ... leading transplant,professional organization, announced a collaborative partnership to jointly,develop further ...
Cached Biology Technology:Poniard Pharmaceuticals Announces European Commission Grants Orphan Medicinal Product Designation to Picoplatin for Treatment of Small Cell Lung Cancer 2Poniard Pharmaceuticals Announces European Commission Grants Orphan Medicinal Product Designation to Picoplatin for Treatment of Small Cell Lung Cancer 3Poniard Pharmaceuticals Announces European Commission Grants Orphan Medicinal Product Designation to Picoplatin for Treatment of Small Cell Lung Cancer 4Respironics to Webcast Fiscal 2008 First Quarter Conference Call 2Astellas Pharma US, Inc. and The International Transplant Nurses Society (ITNS) Collaborate on Content for Transplant Experience Program 2Astellas Pharma US, Inc. and The International Transplant Nurses Society (ITNS) Collaborate on Content for Transplant Experience Program 3
(Date:1/22/2015)... Jan. 22, 2015 Infinisource has launched its new NXG ... model. The G2 sets a higher standard for collecting attendance ... management solution. With plug-and-play installation, touch screen interface and seamless ... a robust time collection solution for the small to mid-size ...
(Date:12/22/2014)... and Markets ( http://www.researchandmarkets.com/research/fx4bg3/the_global ) has ... Watermarking and Fingerprinting Markets" report to their ... This insight provides an overview of ... Watermarking aims to control and monitor piracy by ...
(Date:12/19/2014)... and Markets ( http://www.researchandmarkets.com/research/86ncd6/micro_market ) has announced the ... Security Systems Market" report to their offering. ... perimeter security market is estimated to grow at a CAGR ... holds a larger share in this market, Canada ...
Breaking Biology News(10 mins):Infinisource's NXG series sets new time clock standard 2The Global Watermarking and Fingerprinting Markets 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 2Micro Market Monitor: North America Perimeter Security Systems Market (Intrusion Detection Sensor, Video Surveillance, Communication/Alarm and Notification, Access Control System) 3
... April 27 A group of education and workforce organizations ... during an event on Capitol Hill tonight from 5:00 p.m. ... Building, Room B-338. The honorary host for tonight,s event is the ... of Congress, and it is sponsored by Corinthian Colleges, Inc., an ...
... New Haven, Conn.The physiology of microbes living underground could determine ... warmer Earth, according to a study published online this week ... Colorado State University and the Yale School of Forestry & ... in soil become less efficient over time in converting carbon ...
... vitamin D. It,s one more reason to grab another glass ... Biology conference in Anaheim, California. Milk is the primary source ... of all of the much-needed vitamin D. Using ... 16,000 Americans ages two and older eat, researchers investigated the ...
Cached Biology News:Education and Workforce Organizations Announce New Skills for America -- NOW! Coalition 2Education and Workforce Organizations Announce New Skills for America -- NOW! Coalition 3Microbes contribute less to climate warming 2
... number is a new product number, created ... showing no availability yet, please order under ... customer service for assistance. Feature: ... surface area 21 cm 2 D ...
... and Protein G bind specifically to Fc ... and Protein G conjugates are commonly used ... and immunoglobulin subtypes from serum, hybridoma ascites ... fluids. These reagents are also commonly used ...
... quick (10 min) assay can detect H2O2 ... 10-acetyl-3,7-dihydroxyphenoxazine (ADHP). H2O2 oxidizes ADHP in a ... resorufin (excitation at 530-571 nm, emission at ... peroxidase in a one-step, homogeneous, no wash ...
...
Biology Products: