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The LANCET Published ENDORSE, the Largest Multinational Study Showing That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE Prophylaxis
Date:1/31/2008

DVT), usually in the leg, and pulmonary embolism (PE).

VTE is a common complication among patients hospitalized for major surgery or with a severe medical illness.

About ENDORSE

To date, ENDORSE is the largest international study performed in hospitals selected at random around the world to evaluate VTE risk and prophylaxis practice globally. Patients were enrolled at 358 randomly selected hospitals in 32 countries in Europe, North America, South America, Middle East, Asia, Australia, and North Africa.

The primary objectives of ENDORSE were to identify patients at risk for VTE among patients hospitalized in representative hospitals throughout the world and determine the proportion of at-risk hospitalized patients who receive effective VTE prophylaxis by using the definition of patients at risk of VTE and prophylaxis recommendations provided by the American College of Chest Physicians (ACCP) evidence-based consensus guidelines(2). The secondary objectives of ENDORSE were to define the global rate of medical and surgical patients at risk for VTE, define the overall rate of patients receiving appropriate prophylaxis in medical vs surgical populations and carry out analysis by country and region.

The study included two categories of hospitalized patients: patients in medical wards 40 years of age or older, and patients in surgical wards, 18 years or older. All hospital wards with acute medical or surgical patients were eligible for the survey.

About COR (Center for Outcomes Research)

The Center for Outcomes Research (COR) serves as the scientific coordinating center for a growing number of national and international outcomes registries. COR's responsibilities include maintaining patient and physician confidentiality, design of data collection instruments, data management and publication development.

Established in 1994, COR is an outgrowth of the Worcester Deep Vein Thrombosis Study, a five-year NIH-supported progr
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SOURCE University of Massachusetts Medical School
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