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The LANCET Published ENDORSE, the Largest Multinational Study Showing That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE Prophylaxis
Date:1/31/2008

e and easily preventable disease among patients hospitalized for acute medical and surgical illnesses. Deep vein thrombosis (DVT) and pulmonary embolism are common manifestations of VTE and can contribute significantly to morbidity and mortality.

Commenting on the study, Doctor Ander Cohen, Co-chair of the ENDORSE Steering Committee, said "ENDORSE findings are important from national heath care perspectives since they allow estimation of both the patient welfare and economic benefits of fully applying evidence based VTE prophylaxis among hospitalised medical and surgical patients. If we want to improve hospital patient outcomes, we urgently need to implement hospital-wide strategies to identify all surgical and medical patients at risk for VTE and improve the use of appropriate prophylaxis to prevent VTE."

Despite International and local guidelines on VTE management, ENDORSE results illustrate clearly that there is a gap between guidelines evidence and practice in the hospital setting throughout the world. Lack of awareness and uncertainty about the prevalence of patients at risk of VTE are among the major reasons accounting for this gap(2),(3)

As highlighted by Doctor Victor Tapson, Co-chair of the ENDORSE Steering Committee: "ENDORSE clearly shows that VTE is a critical safety issue in hospitalized patients, as the majority of them are at risk for VTE. The increased use of prophylaxis in the surgical setting for which the benefits of prophylaxis have been accepted for many years compared with medical setting for which trials and guidelines are more recent, shows that we have to increase physician awareness on the benefits of prophylaxis particularly in medical patient."

About venous thromboembolism (VTE)

Venous thromboembolism is a general term used to describe the formation of a blood clot (thrombus) that blocks a vein. This may occur in any part of the venous system, but the most common manifestations are deep-vein thrombosis (
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SOURCE University of Massachusetts Medical School
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