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The LANCET Published ENDORSE, the Largest Multinational Study Showing That the Majority of Hospitalized Patients Surveyed are at Risk for VTE and Many do not Receive Recommended VTE Prophylaxis
Date:1/31/2008

WORCESTER, Massachusetts, February 1 /PRNewswire/ --

- ENDORSE Global Findings Highlight the Need to Urgently Implement Hospital-Wide Strategies to Optimize VTE Management: Systematically Assess Patient Risk for VTE and Provide Appropriate Prophylaxis to Prevent VTE

ENDORSE multinational study (Epidemiologic International Day for the Evaluation of Patients at Risk for Venous Thromboembolism in the Acute Hospital Care Setting) published today in the LANCET(1) demonstrates the high prevalence of patients at risk for VTE (according to the ACCP guidelines) in the world: 52% of hospitalized patients surveyed were at risk for VTE, corresponding to 64% of surgical patients and 42% of medical patients.

ENDORSE demonstrates as well, that recommended prophylaxis is only prescribed to 50% of at-risk patients throughout the world, corresponding to 59% of surgical and 40% of medical patients.

With more than 60,000 patients studied in more than 32 countries encompassing 6 continents the scope of ENDORSE is unprecedented. With a wide range of racial, social, economic and health care environment, ENDORSE gives a unique global and local picture about the extent of the hospitalized patient population at risk for VTE and how these patients are managed.

Doctor Fred Anderson, Director of the Center for Outcomes Research at the University of Massachusetts Medical School who conducted the study commented "ENDORSE shows that a substantial proportion of hospitalized patients are at risk for VTE in each of 32 participating countries. Despite these objective data that VTE risk is important on a global scale, the use of recommended prophylaxis is sub-optimal. This is a complex problem, which will require multiple solutions, including local and national programs of education, guideline development, increased reimbursement for prophylaxis, and addition of VTE prevention to the health-care agenda in every country."

VTE is a major public health issu
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SOURCE University of Massachusetts Medical School
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