Navigation Links
The Immune Tolerance Institute Announces Collaboration with Beckman Coulter Establishing a Multiplatform Immunophenotyping/Immunogenotyping Laboratory
Date:3/31/2008

- Center for Critical Path Immunology created to discover and develop

biomarkers for immune system-related diseases -

SAN FRANCISCO, March 31 /PRNewswire/ -- The Immune Tolerance Institute, Inc. (ITI) today announced a collaboration with Beckman Coulter, Inc. to establish a Center for Critical Path Immunology to investigate the role of the human immune system in disease. This facility, which will be managed by ITI and located initially at Beckman Coulter's Cellular Analysis Business Group in Miami, FL, will integrate state-of-the-art genomic, cellular, proteomic and bioinformatic technology platforms to elucidate immune function in patients with a broad array of immune-related diseases. The Center will work with academic and corporate partners to discover and develop novel, high-value biomarkers that more effectively guide new drug development, including companion diagnostics that match patients with therapies that will provide them the greatest benefit.

"The establishment of ITI's Center for Critical Path Immunology is the first step in bringing to fruition our mission to transform the drug discovery process to one that identifies promising therapies in their early phases of development, and that produces drug candidates that are safer, more highly targeted and effective in treating immune system-related diseases," said Dr. Louis A. Matis, President and Chief Executive Officer of ITI. "We are extremely pleased to be partnering in this initiative with Beckman Coulter, a world leader in the design and development of biomedical testing systems that span research, clinical trials, and diagnostics."

"Advancing 'critical path' science will lead to new approaches to investigate the biological mechanisms of disease and to better predict the clinical efficacy and safety of emerging therapeutics. Such efforts have the potential to enhance drug development and reverse the recent trends that have led to higher failure rates and reduced numbers of annual new drug approvals," said Wade E. Bolton, Ph.D., Vice President of Custom BioPharma Solutions and Services at Beckman Coulter. "Working with the ITI and their distinguished scientific staff, we will be able to identify new solutions and make them available for better patient management."

ITI is advancing a new paradigm for mechanism-based clinical development, designed to better correlate clinical outcomes with underlying disease mechanisms. The company's technologies are being deployed in high-throughput fashion to perform comprehensive cellular, molecular and immunological assays on specimens obtained from patients during clinical trials of emerging immunotherapeutics. The mechanistic data that are generated from these assays will be analyzed in parallel with clinical safety and efficacy data using cutting-edge bioinformatic approaches that leverage new insights at the nexus of emerging life science and information technologies. This approach to critical path science is designed to shorten development times, reduce both costs and failure rates in drug development and guide better informed patient selection for targeted therapies.

The Immune Tolerance Institute (ITI) is a 501(c)(3) non-profit corporation founded in partnership with the University of California, San Francisco (UCSF) to fill critical unmet needs for translating fundamental scientific discoveries into new therapies for the broad range of diseases related to the human immune system, including autoimmune diseases, allergy, asthma, cancer, and cardiovascular and infectious diseases. ITI is a milestone and value-driven not-for-profit company uniquely positioned at the intersection of academia and biopharma that offers a comprehensive constellation of scientific and bio-pharmaceutical industry expertise and services to convert knowledge- based discoveries into market-accessible products for immune system related conditions. The Institute is led by a management team with roots in both biomedical research and the biotechnology industry, and a board of directors including leaders in the field of translational medicine. For more information, visit http://www.iti-immune.org.


'/>"/>
SOURCE Immune Tolerance Institute, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. ImmuneRegen BioSciences Files 8-K that Highlights Enclosed Shareholder Letter Discussing Recent Achievements and Outlook
2. ImmuneRegen Responds to Defense Threat Reduction Agency Request for Information
3. MedImmune Licenses Reverse Genetics Technology to Novartis for Use in Influenza Vaccine Development and Production
4. MedImmune Celebrates Opening of New Pilot Lab at Gaithersburg Headquarters
5. Sanofi Pasteurs Investigational H5N1 Influenza Vaccine Achieves High Immune Response at low Dosage
6. ProImmune Launches New MHC-Peptide Binding Assay for Class II HLA Alleles
7. Advanced Immune Support Formula Licensed From UC Berkeley Launched
8. MedImmune Recognized by Local Volunteer Organization for Its Employees Exceptional Commitment to Community Service within Montgomery County
9. MedImmune to Present RSV Surveillance and Cost-Effectiveness Data at American Academy of Pediatrics National Conference & Exhibition
10. AstraZeneca Bolsters Its Worldwide Biologics Division Through Integration of Cambridge Antibody Technology Into MedImmune
11. MedImmune Announces Seven Key Promotions and New Hires
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/3/2016)... WARRINGTON, Pa. , Feb. 3, 2016 /PRNewswire/ ... biotechnology company focused on developing aerosolized KL4 surfactant ... Board of Directors has approved an inducement award ... Craig Fraser , its newly appointed President and ... the Board,s Compensation Committee on February 1, 2016 ...
(Date:2/3/2016)... 2016 Ascendis Pharma A/S (Nasdaq: ASND ... innovative TransCon technology to address significant unmet medical needs, ... conference.Event:2016 Leerink Partners Global Healthcare Conference Location: , ... 10, 2016 Time:  , 11:55am EST ... An audio webcast of this event will be ...
(Date:2/3/2016)... 3, 2016 New Jersey Health Foundation (NJHF) ... million for researchers in New Jersey ... that demonstrates exciting potential.   James ... the New Jersey Health Foundation Research Grant Program ... educational institutions— Princeton University, Rutgers University, Rowan University ...
(Date:2/3/2016)... ... February 03, 2016 , ... ProMIS Neurosciences ... targets (epitopes) specific to misfolded, propagating strains of Amyloid beta involved in Alzheimer’s ... therapeutics for Alzheimer’s. , Following on from the first misfolded Amyloid beta target ...
Breaking Biology Technology:
(Date:2/1/2016)... -- Wocket® smart wallet ( www.wocketwallet.com ) announces the launch of a new ... Las Vegas , where Joey appeared at the ... Las Vegas , where Joey appeared at the Wocket booth to ... was filmed at the Consumer Electronics Show (CES2016) in Las ... and greet fans. --> --> ...
(Date:1/22/2016)... January 22, 2016 ... addition of the  "Global Behavioral Biometric ... --> http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ) has ... Behavioral Biometric Market 2016-2020"  report to ... and Markets ( http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ) has announced ...
(Date:1/20/2016)... 20, 2016  Synaptics Incorporated (NASDAQ: SYNA ... today announced sampling of S1423, its newest ClearPad ... small screen applications including smartwatches, fitness trackers, and ... and rectangular shapes, as well as thick and ... moisture on screen, while wearing gloves, and supports ...
Breaking Biology News(10 mins):