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The Immune Tolerance Institute Announces Collaboration with Beckman Coulter Establishing a Multiplatform Immunophenotyping/Immunogenotyping Laboratory
Date:3/31/2008

- Center for Critical Path Immunology created to discover and develop

biomarkers for immune system-related diseases -

SAN FRANCISCO, March 31 /PRNewswire/ -- The Immune Tolerance Institute, Inc. (ITI) today announced a collaboration with Beckman Coulter, Inc. to establish a Center for Critical Path Immunology to investigate the role of the human immune system in disease. This facility, which will be managed by ITI and located initially at Beckman Coulter's Cellular Analysis Business Group in Miami, FL, will integrate state-of-the-art genomic, cellular, proteomic and bioinformatic technology platforms to elucidate immune function in patients with a broad array of immune-related diseases. The Center will work with academic and corporate partners to discover and develop novel, high-value biomarkers that more effectively guide new drug development, including companion diagnostics that match patients with therapies that will provide them the greatest benefit.

"The establishment of ITI's Center for Critical Path Immunology is the first step in bringing to fruition our mission to transform the drug discovery process to one that identifies promising therapies in their early phases of development, and that produces drug candidates that are safer, more highly targeted and effective in treating immune system-related diseases," said Dr. Louis A. Matis, President and Chief Executive Officer of ITI. "We are extremely pleased to be partnering in this initiative with Beckman Coulter, a world leader in the design and development of biomedical testing systems that span research, clinical trials, and diagnostics."

"Advancing 'critical path' science will lead to new approaches to investigate the biological mechanisms of disease and to better predict the clinical efficacy and safety of emerging therapeutics. Such efforts have the potential to enhance drug development and reverse the recent trends that have led to higher failure rates and reduce
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SOURCE Immune Tolerance Institute, Inc.
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