Navigation Links
Tengion Scientists Publish Positive Preclinical Findings With Neo-Organ Demonstrating Long-term Durability and Growth With Skeletal Maturation
Date:9/18/2008

Study Showing Results of Tengion Neo-Bladder Augment(TM) Featured in

September Issue of Regenerative Medicine

EAST NORRITON, Pa., Sept. 18 /PRNewswire/ -- Tengion Inc., a clinical stage regenerative medicine company focused on the development of neo-organs and neo-tissues, today announced that the results of a preclinical research study conducted with its Tengion Neo-Bladder Augment(TM) were published in the September issue of the Regenerative Medicine, Vol. 3, Issue 5. The paper, "Long-term durability, tissue regeneration and neo-organ growth during skeletal maturation with a Neo-Bladder Augmentation Construct" was co-authored by Tengion scientists Manuel J. Jayo, D.V.M., Ph.D., Deepak Jain, Ph.D., John W. Ludlow, Ph.D., Richard Payne, Ph.D., Belinda J. Wagner, Ph.D., and Timothy A. Bertram, D.V.M., Ph.D. along with Gordon McLorie, MD from Wake Forest University Baptist Medical Center. The article can be accessed via the website http://www.futuremedicine.com/doi/abs/10.2217/17460751.3.5.671

The preclinical study, in which either a Neo-Bladder Augment or the subject's own native urinary bladder was surgically implanted following an 80% cystectomy and evaluated clinically at one, three, six, nine, 12, 18 and 24 months - showed that the Tengion Neo-Bladder Augment regained and maintained native bladder histology by three months. The study also demonstrated that the Neo-Bladder Augment regained baseline capacity at three to six months and baseline compliance by 12-24 months. Importantly, the Neo-Bladder Augment continued to adapt in size and function with overall animal growth, or skeletal maturation.

"The results of this study are very encouraging for our overall Neo-Bladder Augment program and, specifically, for our ongoing Neo-Bladder Augment pediatric clinical trial. The children with spina bifida in that trial are continuing to grow and mature and our goal is for the Neo-Bladder Augment to demonstrate durability and the ability to adapt to growth-related changes - as it has done in this pre-clinical model," said Dr. Bertram, Senior Vice President, Science and Technology of Tengion, "Tengion is truly excited to continue to share positive research results that help to further advance our neo-organ pipeline, and continue to validate our Autologous Organ Regeneration Platform(TM)."

About Tengion

Tengion, a clinical stage biotechnology company, focuses on developing, manufacturing and commercializing human neo-organs and neo-tissues using our Autologous Organ Regeneration Platform(TM). Tengion uses biocompatible materials and a patient's own (autologous) cells to create a functional neo-organ or neo-tissue that is designed to catalyze the body's innate ability to regenerate. Tengion's product candidates may ultimately address the most critical problems facing organ and tissue failure patients, enabling people to lead healthier lives without donor transplants or the side effects of related therapies.


'/>"/>
SOURCE Tengion Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related biology technology :

1. Preclinical Efficacy Data Demonstrate Ability of Tengions Neo-Bladder Augment to Restore Bladder Function
2. Tengion to Present at Merrill Lynch Global Pharmaceutical, Biotechnology & Medical Device Conference
3. Tengion Appoints Jeff Randall to Board of Directors
4. Tengion Announces European Orphan Drug Designation for Neo-Bladder Augment
5. Tengion Appoints Mark Stejbach Vice President of Marketing & Commercial Planning
6. Gladstone scientists uncover potential mechanism of memory loss in Alzheimers disease
7. Three Studies by Independent Scientists Highlighting Pressure Cycling Technology (PCT) to be Presented this Week at the British Mass Spectrometry Societys 29th Annual Meeting
8. Social Network for Scientists Marks Ten Years Online
9. Scientists synthesize memory in yeast cells
10. Scientists synthesize memory in yeast cells
11. University of Leicester scientists discover technique to help friendly bacteria
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2016)... ... , ... The need for blood donations in South Texas and across the nation is growing. ... Tissue Center, blood donations are on the decline. In fact, donations across the country are ... in South Texas in the last four years alone. , There is no substitute for ...
(Date:5/23/2016)... LONDON , May 23, 2016 ... Boost Efficiency by 40% - Frontage Implement a Single ... Enforce Quality, Compliance and Traceability Within the Bioanalytical lab ... the United States and China ... deployed across its laboratory facilities. In addition to serving as the ...
(Date:5/20/2016)... ... 2016 , ... The leading Regenerative Veterinary Medicine Company, VetStem Biopharma ., ... over 100 of their own patients with the VetStem Cell Therapy. Each of these ... for their patients. , The veterinarians are Dr Ross Rich former owner of ...
(Date:5/19/2016)... ... ... Anton Paar USA, located in Ashland, Virginia is pleased to announce that ... adds a third office building to the current facilities. , Growth is nothing ... along with office space adjacent to the previous main building. Through remodels and new ...
Breaking Biology Technology:
(Date:3/15/2016)... New York , March 15, 2016 ... new market report published by Transparency Market Research "Digital Door ... Trends and Forecast 2015 - 2023," the global digital door ... US$ 731.9 Mn in 2014 and is forecast to grow ... 2023. Growth of micro, small and medium enterprises (MSMEs) across ...
(Date:3/11/2016)... 11, 2016 http://www.apimages.com ) - --> ... is available at AP Images ( http://www.apimages.com ) - ... used to produce the new refugee identity cards. DERMALOG will be ... CeBIT in Hanover next week.   --> ... be used to produce the new refugee identity cards. DERMALOG will ...
(Date:3/9/2016)... YORK , March 9, 2016 This ... and future states of the RNA Sequencing (RNA Seq) ... segments such as instruments, tools and reagents, data analysis, ... Analyze various segments of the RNA-Sequencing market such as ... services Identify the main factors affecting each segment and ...
Breaking Biology News(10 mins):