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Tarsa Therapeutics and Unigene Present Preclinical Data Suggesting Calcitonin May Have Utility in Combination Therapy for the Treatment of Osteoarthritis
Date:9/24/2010

oncept that calcitonin may have a role in reducing cartilage degradation and bone loss as part of a combination therapy for treating osteoarthritis.  In addition, in our studies the synergistic effects were achieved using low doses of the compounds.  This type of combination therapy may have the potential to treat osteoarthritis more effectively while reducing the safety concerns associated with higher doses of existing anti-arthritis agents."

The annual OARSI Congress is a global forum for all people interested and involved in osteoarthritis research and treatment: basic scientists from academia and industry, clinical investigators, physicians (radiologists, rheumatologists, orthopaedic surgeons, etc.), allied health professionals and policy makers.  It is being held in Brussels, Belgium September 23-26, 2010.  For more information, visit www.oarsi.org/meetings/10Congress/index.php.

About Tarsa TherapeuticsTarsa Therapeutics is developing an oral formulation of calcitonin for the treatment of osteoporosis.  Calcitonin is a peptide hormone that inhibits bone resorption, the underlying process that can result in osteoporosis.  Availability of an oral formulation is expected to generate wider use of this established osteoporosis treatment, which currently is available only in injectable and intranasal formulations.  Tarsa's oral calcitonin has generated promising data in Phase II studies, and the ORACAL study, a global Phase III clinical trial, has completed patient enrollment.  Tarsa is based in Philadelphia, PA.  For more information, visit www.tarsatherapeutics.com.

About Unigene Laboratories, Inc.  Unigene Laboratories, Inc. is a leader in the design, delivery, manufacture and development of peptide-based therapeutics.  The Company is building a robust portfolio of proprie
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SOURCE Tarsa Therapeutics, Inc.
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