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TB Alliance and AstraZeneca Form Research Collaboration to Fight Tuberculosis
Date:5/3/2010

NEW YORK and BANGALORE, India, May 3 /PRNewswire/ -- The Global Alliance for TB Drug Development (TB Alliance) and AstraZeneca announced today at the 2010 BIO International Convention that they have entered into a research collaboration agreement to accelerate the discovery, development and clinical use of drugs against tuberculosis (TB), including drug resistant strains of the disease. One in five patients with TB are resistant to at least one of today's standard first-line TB drugs according to the most recent data from the World Health Organization.

Under the agreement, the TB Alliance and AstraZeneca will both contribute promising TB drug discovery projects into a joint portfolio that will be co-developed by both parties. Sharing resources and creating a seamless path to clinical-stage development will improve the efficiency of both organizations' research programs.  By focusing on novel compound classes, the drug candidates identified by the collaboration are likely to be effective against both drug-resistant and drug-sensitive tuberculosis. The financial terms were not disclosed.

The initial set of projects contributed by the TB Alliance results from its ongoing collaboration with several world-leading researchers at the University of Pennsylvania, Rutgers University and New York Medical College. AstraZeneca's projects come from its TB research center in Bangalore, India. The joint portfolio will be resourced by a core group of scientists based at AstraZeneca's TB research center in Bangalore with expertise and funding provided by both organizations.

Promising compounds identified in this collaboration
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