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Systems Medicine (SM), a Subsidiary of Cell Therapeutics, Inc. (CTI), Announces Execution of CRADA with NCI/NIH to Develop Potential Cancer Treatments Targeting the Insulin Growth Factor (IGF) Pathway
Date:8/22/2007

s biology approach to drug development, combining pharmacogenomics and bioinformatics with experienced preclinical, clinical, and regulatory expertise to find and exploit a specific cancer's 'context-of-vulnerability.' Specifically, SM defines the molecular and genetic alterations (context) that cause cancer cells to be particularly sensitive (vulnerable) to a drug or combination of drugs-the 'context-of-vulnerability'.

About the National Cancer Institute's Center for Cancer Research Nanobiology Program

The National Cancer Institute (NCI), part of the NIH, an agency under the U.S. Department of Health and Human Services, is the world's pre-eminent cancer research organization. The NCI engages in certain fundamental activities which include: conducting and fostering cancer research; reviewing and approving grant-in-aid applications to support promising research projects on the causes, prevention, diagnosis, and treatment of cancer; collecting, analyzing, and disseminating the results of cancer research conducted in the United States and elsewhere; and training and instruction in the diagnosis and treatment of cancer. The Center for Cancer Research Nanobiology Program (CCRNP) serves as a catalyst to move forward multidisciplinary efforts in the area of Cancer Nanotechnology. The program forms partnerships with the NCI's broader Nanotechnology Program, other CCR basic research laboratories and clinical branches, as well as with the broader extramural community, to enhance the interface of physics and computational sciences with biology.

This press release includes forward-looking statements that involve a number of risks and uncertainties, the outcome of which could materially and/or adversely affect actual future results. Specifically, the risks and uncertainties that could affect the success of developments realized by SM under the CRADA, SM's ability to successfully negotiate for the rights to further develop, market and sell any products that are
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SOURCE Cell Therapeutics, Inc.
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