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Synvista Therapeutics Announces Availability of Haptoglobin Genotyping Technology at The Annual Scientific Sessions of the American Heart Association
Date:11/10/2008

New Data Presented at the Meeting Report the Use of Haptoglobin Typing to Predict Cardiovascular Risk, and Benefit From Tight Glycemic Control in Diabetics

MONTVALE, N.J., Nov. 10 /PRNewswire-FirstCall/ -- Synvista Therapeutics, Inc. (Amex: SYI) today announced at the Annual Scientific Sessions of the American Heart Association, underway in New Orleans, that a new clinical test to determine haptoglobin (Hp) genotype utilizing intellectual property licensed from Synvista is now available. Knowledge of Hp genotype may help physicians to assess cardiovascular risk and guide treatment choices in their patients with diabetes. Several presentations relating to the Company's technology are being delivered during the Scientific Sessions, including one showing that older individuals with diabetes mellitus and the Hp2-2 genotype (Hp2-2 Diabetes) demonstrate a significantly higher mortality rate from cardiovascular disease than those who do not have the Hp 2-2 genotype; and another demonstrating that tight glycemic control reduces the incidence of heart attack (myocardial infarction - MI) only in Hp2-2 Diabetes.

The test, which was developed and validated by ARUP Laboratories, will be performed under a license agreement with Synvista in ARUP's CLIA-certified laboratory. In addition, Synvista has developed its own test utilizing different technology than ARUP which it intends to market as a diagnostic kit after submitting a 510(k) to, and obtaining clearance from, the U.S. Food and Drug Administration (FDA).

"We are extremely pleased that our intellectual property will have a role in making personalized medicine a reality," said Noah Berkowitz, M.D., President and CEO of Synvista Therapeutics. "We believe that the ease of use of o
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SOURCE Synvista Therapeutics, Inc.
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