Navigation Links
Synthetic Biologics Announces Completion of Enrollment in 164 Patient Clinical Trial of Oral Trimesta™ for Multiple Sclerosis
Date:3/14/2012

is available at http://www.clinicaltrials.gov/ct2/show/NCT00451204.

Current sales of injectable disease-modifying therapies for MS are estimated at $8.9 billion annually.  According to various reports, sales of oral disease-modifying therapies for MS, of which Trimesta™ if and when approved would be in such class, are anticipated to exceed $5 billion annually by 2017.

"We are pleased to complete the enrollment of a total of 164 patients in this landmark MS trial," said Rhonda Voskuhl, M.D., Director, University of California, Los Angeles (UCLA) Multiple Sclerosis Program, UCLA Department of Neurology, and lead Principal Investigator of the trial. "In the United States alone, over 200 people per week are diagnosed with MS, and approximately 70% of them are women. Typically, relapsing-remitting MS is distinguished from the other forms of MS by the relapses, or attacks of declining neurologic function, followed by periods of remission. With this trial evaluating oral estriol (Trimesta), we would expect to demonstrate a reduction in the rate of relapses in these MS patients."

About Trimesta (oral estriol)

Trimesta is Synthetic Biologics' proprietary drug candidate for the treatment of relapsing-remitting MS in women. Estriol has been approved and marketed for over 40 years throughout Europe and Asia for the treatment of post-menopausal hot flashes. It has never been approved by the FDA for any indication in the United States.

It has been scientifically documented that pregnant women with certain autoimmune diseases experience a spontaneous reduction of disease symptoms during pregnancy, particularly in the third trimester. The PRIMS (Pregnancy In Multiple Sclerosis) study, a landmark clinical study published in the New England Journal of Medicine followed 254 women with MS during 269 pregnancies, and for up to one year after delivery. The PRIMS s
'/>"/>

SOURCE Synthetic Biologics, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Synthetic Biologics to Present at ROTH Annual Growth Stock Conference
2. Adeona Becomes Synthetic Biologics, Inc.
3. Startling results in synthetic chemistry presented in Nature Chemistry
4. New England Biolabs Signs Agreement with Synthetic Genomics Inc. to Launch Gibson Assembly™ Master Mix for Molecular and Synthetic Biology Applications
5. Synthetic Genomics Inc. Hires Industry Leader George E. Stagnitti to Head Food and Nutritional Products Development Program
6. Synthetic Biology: Emerging Global Markets
7. "Sitting Ducks" No Longer: Advance Flu Warning Permits Creation of Replikins Custom Synthetic Flu Vaccine in Animals
8. Synthetic Genomics Inc. and Plenus, S.A. de C.V. Form New Sustainable Agriculture Company, Agradis, Inc. to Develop and Commercialize Products Using Genomic Technologies
9. Swedish University Hospital Improves Monitoring of Treatment Efficacy in Multiple Sclerosis With Synthetic MRI Innovation
10. Kuros Announces Allowance of European Patent for Synthetic Biomaterials
11. Synthetic Genomics Inc. Appoints Joseph Mahler as Chief Financial Officer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... , July 28, 2014 Research and ... Particle Size Analysis Market 2014-2018" report to their offering. ... Particle size analysis is a technique used to determine the ... or liquid. It is crucial to analyze the size of ... Therefore, particle size analysis is performed to determine the behavior ...
(Date:7/28/2014)... (PRWEB) July 28, 2014 The National ... in Muncie IN, is pleased to announce that it ... National Museum of the United States Air Force. , ... year-long process that concluded this spring with an on-site ... Dayton, OH museum. , The National Museum of ...
(Date:7/26/2014)... 2014 Canada Endoscopy Visualization Systems ... on the Canada Endoscopy Visualization Systems market. The ... volume (in units) and average prices (in US ... Systems, Mid-Range Endoscopy Visualization Systems and Low-End Endoscopy ... http://www.marketresearchreports.biz/analysis/213254 . , The report also provides company ...
(Date:7/25/2014)... Albany, NY (PRWEB) July 26, 2014 ... Trials Review, H2, 2014" provides data on the ... This report provides elemental information and data relating ... Cerebral Stroke. , View full global Ischemic Stroke ... It includes an overview of the trial numbers ...
Breaking Biology Technology:Global Particle Size Analysis Market 2014-2018 2AMA’s National Model Aviation Museum Granted Full Civilian Museum Certification by the National Museum of the United States Air Force 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 2Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 3Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 4Canada Endoscopy Visualization Systems Market Outlook to 2020: MarketResearchReports.Biz 5Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 2Ischemic Stroke and Cerebral Stroke Global Clinical Trials Review H2, 2014: MarketResearchReports.Biz 3
... Companies looking to thrive in an increasingly competitive atmosphere are ... on one rather unusual method: speed-networking, a concept based on ... to this story now using RealPlayer , ,Its not ... eat the slow. That phrase was used to kick off ...
... still beaming on Saturday, a day after the Legislatures upper ... and build a stronger in-state network for entrepreneurs , ,Not ... fall, but this is the most important so far to ... with Democrats and Republicans alike in helping to pass the ...
... - EraGen Biosciences , a Wisconsin-based life ... and technologies that accelerate the drug discovery process, ... that it has selected ITOCHU Corporation ... integrated phylogenomics product, Master Catalog , in ...
Cached Biology Technology:Looking to be Competitive? Try Speed Networking 2Senate Passes an Investment Capital Package; the Assembly Should Follow Suit 2Senate Passes an Investment Capital Package; the Assembly Should Follow Suit 3EraGen Expands in Japan 2
(Date:7/25/2014)... Prediabetes and Diabetes increasingly consume the healthcare ... immediate attention. , To address the ... impacting low-and middle-income countries, global leaders in ... research in diabetes prevention and development of ... important text. , This book on ...
(Date:7/25/2014)... tractography (DTT), which is derived from diffusion tensor ... motor tracts, such as the corticospinal tract, the ... The corticospinal tract is known to be a ... human brain. Several studies have reported on injury ... addition, some studies have demonstrated recovery of a ...
(Date:7/25/2014)... detected an unknown interaction between microorganisms and salt. When ... droplet of salt water and is left to dry, ... biosaline 3D morphologically complex formations, where they hibernate. Afterwards, ... discovery was made by chance with a home microscope, ... journal and may help to find signs of ...
Breaking Biology News(10 mins):What constitutes an effective response to the global 'diabesity' tsunami? 2Bacteria manipulate salt to build shelters to hibernate 2
... field trials of Miscanthus x giganteus , a towering ... yields, though reduced somewhat after five years of growth, are ... ), another perennial grass used as a bioenergy feedstock. ... yields found in earlier studies of the crop in Europe, ...
... Sciences (AIBS) has selected three individuals as winners of ... This is the third year AIBS has sponsored ... members of the scientific community to showcase for the ... informing natural resources management, addressing climate change, improving human ...
... For some 5,000 years, cultivated silkworms have been spinning ... finest clothing. But current dyeing practices produce wastewater that ... a new, "greener" dyeing method in which they coax ... leaves. Their findings are published in the journal ...
Cached Biology News:The first decade: Team reports on US trials of bioenergy grasses 2The first decade: Team reports on US trials of bioenergy grasses 3AIBS announces winners of Faces of Biology photo competition 2
Lingo-1 (K-13)...
... well-characterized tissue-specific stem cells that exhibit remarkable ... life-long maintenance of the hematopoietic system. HSC ... bone marrow where hematopoiesis is continuously taking ... cord blood, fetal liver, adult spleen and ...
Human DEP-1/CD148 Fluorescein MAb (Clone 143-41) Protein Family: Granulocyte Markers, Monocyte Markers, Phosphatases & Regulators, Other Dendritic Cell Molecules...
MOUSE ANTI PORCINE SLA 1:FITC Immunogen: Porcine peripheral blood mononuclear cells....
Biology Products: