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Surveyed Physicians Indicate that Xtandi is Prescribed to Nearly One Quarter of Metastatic Castrate-Resistant Prostate Cancer Patients Who Have Failed to Respond to Prior Docetaxel Treatment
Date:5/6/2013

EXTON, Pa., May 6, 2013 /PRNewswire/ -- BioTrends Research Group, one of the world's leading research and advisory firms for specialized biopharmaceutical issues, finds that, at six months following launch of Xtandi (Astellas Pharma/Medivation's enzalutamide), surveyed urologists and medical oncologists prescribed Xtandi to a respective 19 percent and 24 percent of their metastatic castrate-resistant prostate cancer (mCRPC) patients who have failed to respond or had very rapid progression from docetaxel (Sanofi's Taxotere, generics) treatment. In six months' time, surveyed respondents expect to prescribe Xtandi to 35-39 percent of these mCRPC patients, making Xtandi the patient share leader in this patient population.

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The second wave of the LaunchTrends®: Xtandi report series, fielded six months following the launch of Xtandi in the United States, finds that 30 percent of surveyed urologists have prescribed Xtandi in clinical practice compared with 43 percent of surveyed medical oncologists. In contrast, data published just one month post launch of Xtandi revealed that less than 10 percent surveyed urologists had prescribed Xtandi in clinical practice (i.e., outside of clinical trials), compared with 39 percent of their medical oncologist counterparts. Lack of familiarity with Xtandi and because many eligible patients are already receiving Zytiga (Johnson & Johnson/Janssen Biotech/Janssen Cilag's abiraterone) are key reasons cited by surveyed respondents for not having prescribed Xtandi yet. However, the majority of current non-prescribing urologists (61 percent) and medical oncologists (88 percent) surveyed tell us that they expect to prescribe Xtandi within the next six months.

The findings also reveal that if Xtandi successful
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SOURCE BioTrends Research Group
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