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Surveyed Experts Indicate That Byetta LAR and Victoza Have Advantages Over Actos in the Treatment of Type 2 Diabetes
Date:3/24/2009

Byetta LAR Will Earn Decision Resources' Clinical Gold Standard Status for Type 2 Diabetes in 2012, According to a New Report from Decision Resources

WALTHAM, Mass., March 24 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed endocrinologists indicate that a therapy's effect on glycosylated hemoglobin A1c (HbA1c) is the attribute that most influences their prescribing decisions in type 2 diabetes. Clinical data and the opinions of interviewed thought leaders indicate that Alkermes/Amylin/Eli Lilly's Byetta LAR and Novo Nordisk's Victoza have advantages in this attribute over Takeda's Actos, the sales-leading agent in the market.

The new report entitled Type 2 Diabetes: Endocrinologists' Satisfaction with Inexpensive Metformin Sets High Hurdles for Emerging Agents finds that a drug that is substantially more effective than metformin (Bristol-Myers Squibb/Merck Serono's Glucophage, generics) at reducing HbA1c and offers improvements in terms of convenience would earn a 33 percent patient share in type 2 diabetes in the United States and a 30 percent patient share in Europe, according to surveyed U.S. and European endocrinologists.

In 2008, Decision Resources' proprietary clinical gold standard for type 2 diabetes was Byetta (exenatide), owing to its efficacy and its propensity to cause weight loss. Based on available data and expert opinion, Byetta LAR will earn gold-standard status for type 2 diabetes in 2012, following its approval for the indication in that year.

"Byetta LAR has competitive advantages in terms of delivery compared with the current gold standard," said Decision Resources Analyst Caroline Gates. "Furthermore, in a 30-week, randomized, open-label clinical trial involving nearly 300 type 2 diabetics, patients treated with Byetta LAR demonstrated statistically significant
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SOURCE Decision Resources
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