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Super-resolution X-ray microscopy
Date:7/17/2008

This release is available in French.

This release is available in German.

A novel super-resolution X-ray microscope developed by a team of researchers from the Paul Scherrer Institut (PSI) and EPFL in Switzerland combines the high penetration power of x-rays with high spatial resolution, making it possible for the first time to shed light on the detailed interior composition of semiconductor devices and cellular structures.

The first super-resolution images from this novel microscope will be published online July 18, 2008 in the journal Science.

"Researchers have been working on such super-resolution microscopy concepts for electrons and x-rays for many years," says EPFL Professor and team leader Franz Pfeiffer. "Only the construction of a dedicated multi-million Swiss-franc instrument at PSI's Swiss Light Source allowed us to achieve the stability that is necessary to implement our novel method in practice."

The new instrument uses a Megapixel Pilatus detector (whose big brother will be detecting collisions from CERN's Large Hadron Collider), which has excited the synchrotron community for its ability to count millions of single x-ray photons over a large area. This key feature makes it possible to record detailed diffraction patterns while the sample is raster-scanned through the focal spot of the beam. In contrast, conventional x-ray (or electron) scanning microscopes measure only the total transmitted intensity.

These diffraction data are then treated with an algorithm conceived by the Swiss team. "We developed an image reconstruction algorithm that deals with the several tens of thousands of diffraction images and combines them into one super-resolution x-ray micrograph," explains PSI researcher Pierre T
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Contact: Franz Pfeiffer
franz.pfeiffer@epfl.ch
41-763-201-045
Ecole Polytechnique Fdrale de Lausanne
Source:Eurekalert

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