Navigation Links
Study suggests: Blood test can differentiate between benign lung nodules and early stage lung cancer
Date:10/19/2013

etter understand health and disease," said Lee Hood, M.D., Ph.D., co-author of the study; co-founder and board member of Indi; and co-founder of the Institute for Systems Biology (ISB), which collaborated with Indi on the study. "These systems approaches convert blood into a window that will readily allow us to distinguish health from diseaseand if disease, which disease. This is just the beginning. The principles used to develop this classifier should be applicable to a range of unmet diagnostic medical needs."

The final group of proteins was validated in a second study that utilized an independent set of 104 plasma samples (52 with cancer; 52 benign), including successful validation of the classifier at a completely new hospital site. As with the earlier study, each malignant sample was matched with a benign sample of the same age, gender, nodule size and participating clinical site. In this study, the classifier was found to have a negative predictive value (NPV) of 90% meaning that patients whose test results identify protein markers at concentrations suggesting that their nodule is "likely benign" may have a high probability of that classification being correct.

"We believe this technology, when applied to a commercial protein expression test, will be of tremendous interest to pulmonologists," said Albert A. Luderer, Ph.D., chief executive officer, Indi. "Clinicians encounter patients with lung nodules in their practices on a regular basis, which often lead to invasive procedures. We expect that a non-invasive test based on Indi's technology may be able to assist physicians in determining which nodules do not require risky and costly clinical interventions. Eliminating those invasive procedures on benign patients should lead to significant savings in the healthcare system."

The STM paper is titled "A Blood-Based Proteomic Classifier for the Molecular Characterization of Pulmonary Nodules" and included the participation and/or the
'/>"/>

Contact: Eliot Dobris
eliot@eliotdobris.com
415-902-1241
Indi (Integrated Diagnostics)
Source:Eurekalert

Page: 1 2 3 4

Related biology technology :

1. Positive Clinical Study Results for BSPs HyperQ Technology
2. 15-Minute Data From Phase 3 Study of Avanafil Featured as a Late Breaking Abstract at SMSNA Annual Meeting
3. DermTechs Non-invasive Melanoma Detection Assay Poised to Enter Clinical Validation Study
4. Marshall study shows nanoparticles used as additives in diesel fuels can travel from lungs to liver
5. Clionsky Neuro Systems (CNS-Neuro) Announces Publication of Study Finding Elderly Patients Unable to Recognize Their Memory Loss
6. Convergence Pharmaceuticals Initiates Phase I Multiple Ascending Dose Study for CNV2197944
7. AtheroNova Inc. Preclinical Study Demonstrates 95% Reduction in Arterial Plaque Formation
8. Singapore scientists lead human embryonic stem cell study
9. GeneTex Antibody Company to Launch New Line of Primary Antibodies for the Study of Spindle Assembly
10. Nutra Pharma Announces Publication of a New Mechanism Study of Alpha-Cobratoxin in the Treatment of Pain
11. Metabolex Announces Positive Results From its Clinical Study of Arhalofenate in Combination With Febuxostat
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... NC (PRWEB) September 19, 2014 ... Biobased Product Label for its Organic Cotton . ... product’s amount of renewable biobased ingredients meets or exceeds ... intermediate materials composed in whole or in significant part ... logo/label will allow our Organic cotton to be immediately ...
(Date:9/19/2014)... The new , Healthcare and Life Sciences Review ... PharmaBoardroom.com for free download , looks beyond ... economy in 2009, and the austerity measures that followed, to ... times of trouble. "Despite the crisis, ... and the general conditions to invest are favorable to the ...
(Date:9/18/2014)... DALLAS , Sept. 18, 2014 /PRNewswire-iReach/ -- ... and China Acetic Acid Industry" and "2014 Deep ... Industry" reports to its research database. ... 2014 Deep Research Report on Global and China ... research report on China ...
(Date:9/18/2014)... Texas (PRWEB) September 18, 2014 ... Chancellor John Sharp, Texas A&M Health Science Center ... U.S. Department of Health and Human Services (HHS), ... dedicated a national pandemic influenza vaccine manufacturing facility ... as an anchor for the Texas A&M Biocorridor ...
Breaking Biology Technology:Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 2Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 3Acetic Acid Market & Sodium Stannate Industry (China, Global) Research Report 4Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 2Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 3Texas A&M Dedicates National Pandemic Influenza Vaccine Manufacturing Facility, on Track for 2016 Start-Up Phase 4
... Advanced Biofuels, LLC, a joint venture between BP ... into collaboration with Fagen, Inc. for the introduction ... is the world,s most experienced biofuels engineering, procurement ... than any other company.  They are the largest, ...
... Exciting new data presented today at the ... role in the development of diabetes and non-alcoholic fatty ... . Though an early stage animal model, the French ... with gut microbiota transplantation - the engrafting of new ...
... , Luis Montaner from the Wistar Institute, Philadelphia, USA ... model to a cohort of HIV-infected patients on antiretroviral ... be used to optimize laboratory capacity in settings where ... is not intended to replace CD4 count testing or ...
Cached Biology Technology:Butamax™ and Fagen Announce Collaboration to Retrofit Ethanol Plants for Biobutanol Production 2Gut Microbiota Transplantation may Prevent Development of Diabetes and Fatty Liver Disease 2Gut Microbiota Transplantation may Prevent Development of Diabetes and Fatty Liver Disease 3
(Date:9/19/2014)... that legume plants regulate their symbiotic relationship with ... transmitted through the plant structure from leaves into ... nodules in the roots. This collaborative study was ... Basic Biology, the Graduate University for Advanced Studies ... Science in Japan. , Legumes, an important ...
(Date:9/18/2014)... in the primitive brainstem has revealed how we fall ... of Medicine and the University at Buffalo School of ... "sleep node" identified in the mammalian brain whose activity ... deep sleep. , Published online in August in ... of all of the brain,s sleep-promoting activity originates from ...
(Date:9/18/2014)... can operate inside the bore of an MRI scanner ... research partnership program at Brigham and Women,s Hospital in ... in conjunction with real-time MRI images, can make prostate ... discomforting for the patient. The novel system also has ... precision. , Developed by a team of robotics engineers ...
Breaking Biology News(10 mins):For legume plants, a new route from shoot to root 2No sedative necessary: Scientists discover new 'sleep node' in the brain 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5
... A new report published by an independent global ... system needs an immediate transformation to meet current and ... The Commission on Sustainable Agriculture and Climate Change today ... policy responses to the global challenge of feeding the ...
... 2011 For the first time, researchers have ... of the enzymes involved in degrading persistent pollutants ... Professor Michel Sylvestre of Centre INRSInstitut Armand-Frappier in ... not only to help develop effective biocatalysts for ...
... (University of Turku and VTT Technical Research Centre of Finland) ... Institute for Health and Welfare) have discovered that the SHARPIN ... leading journal, the study concludes that SHARPIN regulates the movement ... cancer cells. It is likely that the discovery will also ...
Cached Biology News:Global commission delivers food security policy recommendations 2Global commission delivers food security policy recommendations 3
... siSolutions siRNA Custom Synthesis ... effective duplex RNA to knockdown ... 21-mers (19 RNA base pairs ... recently-published 27-mers, or other lengths ...
EDG-1 Western blot control Source: Cell Lysate Application: Western Blotting Control...
Hybridization cassette for one slide...
Request Info...
Biology Products: