Navigation Links
Study suggests: Blood test can differentiate between benign lung nodules and early stage lung cancer
Date:10/19/2013

SEATTLE, October 16, 2013 Indi (Integrated Diagnostics), an emerging leader in molecular diagnostics, today announced the results of a major study which suggests that quantifying a combination of blood proteins can distinguish between benign lung nodules and early-stage lung cancer with high probability. The study, which was published today in Science Translational Medicine (STM), suggests that when this group of proteins (or 'classifier') is detected, and their relative concentrations are used to identify a patient's lung nodule (a round lesion of up to three cm) as benign, the classifier result is correct more than 90 percent of the time. This multiple protein expression classifier, which is intended to assist physicians with the early diagnosis of lung nodules, uses a highly sensitive analytic technique called multiple reaction monitoring mass spectroscopy (MRM-mass spec). This laboratory-based analytical method combined with sophisticated bioinformatics and systems-biology approaches allowed the researchers to assess the diagnostic power of 371 potential lung cancer biomarkers in millions of different combinations before settling on the diagnostic classifier (set of biomarkers) that these data indicate is most effective.

"These studies suggest that Indi's technology is capable of detecting the molecular signature of lung cancer by measuring the presence of multiple proteins in a patient's blood," said Paul Kearney, Ph.D., president and chief science officer, Indi and senior author of the STM paper. "We are very pleased that these data suggest we have achieved a 90 percent probability with this diagnostic classifier. Doing so required performing an unbiased search for biomarkers involved in early-stage lung cancer, considering all potential disease pathways. Using MRM-mass spec as the platform was essential because it makes it feasible to simultaneously measure hundreds of proteins at once. Conducting the broadest possible search for biom
'/>"/>

Contact: Eliot Dobris
eliot@eliotdobris.com
415-902-1241
Indi (Integrated Diagnostics)
Source:Eurekalert

Page: 1 2 3 4

Related biology technology :

1. Positive Clinical Study Results for BSPs HyperQ Technology
2. 15-Minute Data From Phase 3 Study of Avanafil Featured as a Late Breaking Abstract at SMSNA Annual Meeting
3. DermTechs Non-invasive Melanoma Detection Assay Poised to Enter Clinical Validation Study
4. Marshall study shows nanoparticles used as additives in diesel fuels can travel from lungs to liver
5. Clionsky Neuro Systems (CNS-Neuro) Announces Publication of Study Finding Elderly Patients Unable to Recognize Their Memory Loss
6. Convergence Pharmaceuticals Initiates Phase I Multiple Ascending Dose Study for CNV2197944
7. AtheroNova Inc. Preclinical Study Demonstrates 95% Reduction in Arterial Plaque Formation
8. Singapore scientists lead human embryonic stem cell study
9. GeneTex Antibody Company to Launch New Line of Primary Antibodies for the Study of Spindle Assembly
10. Nutra Pharma Announces Publication of a New Mechanism Study of Alpha-Cobratoxin in the Treatment of Pain
11. Metabolex Announces Positive Results From its Clinical Study of Arhalofenate in Combination With Febuxostat
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... Continuing its award-winning streak, Nerium International, ... MarCom Awards for outstanding creative achievement by its marketing ... Award, the organization’s top honor, in the Branding category ... in April of this year. The event showcased top ... Nerium was awarded a Gold MarCom Award in the ...
(Date:11/26/2014)... WILMINGTON, DE (PRWEB) November 26, 2014 ... MPN Heroes recognition reception on December 5, 2014, in ... annual meeting. The MPN Heroes event will honor clinicians, ... the field of myeloproliferative neoplasms (MPNs). , Special ... will discuss his family's cancer journey at the reception. ...
(Date:11/26/2014)... WARREN, N.J. , Nov. 25, 2014  Roka Bioscience, ... focused on providing advanced testing solutions for the detection of ... will present at the Piper Jaffray  26 th Annual ... conference will be held at The New York Palace in ... During this presentation, material information concerning the Company, its operations, ...
(Date:11/24/2014)...   First published ... Elsevier , a world-leading provider of scientific, technical ... the launch of the latest title in the Current ... Food Science . Current ... new platform to keep up-to-date with the expanding volume of ...
Breaking Biology Technology:Nerium International™ Wins One Platinum, Two Gold MarCom Awards 2CURE Magazine and Incyte to Honor MPN Heroes 2CURE Magazine and Incyte to Honor MPN Heroes 3CURE Magazine and Incyte to Honor MPN Heroes 4Roka Bioscience to Present at the Piper Jaffray Healthcare Conference 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 2Elsevier Announces Launch of New Journal: Current Opinion in Food Science 3
...  MiMedx Group, Inc. (OTCBB: MDXG), an integrated developer, ... and bioimplants processed from human amniotic membrane, announced ... to sell convertible notes and warrants has been ... commenced on October 15, 2011, the Company received ...
... Dec. 27, 2011  While many Americans are resolving to address ... shows that some adults are looking to find answers to ... The survey, which was commissioned by Identigene, the ... Identigene DNA Paternity Test, the only paternity test available at ...
... 27, 2011 Cord Blood America, Inc . ( ... umbilical cord blood stem cell preservation company focused ... families nationwide and internationally, is pleased to announce it has ... Las Vegas laboratory for the National Children,s Leukemia Foundation (NCLF), ...
Cached Biology Technology:MiMedx Group Completes $5,000,000 Private Placement 2MiMedx Group Completes $5,000,000 Private Placement 3Survey Reveals Paternity Questions Loom for More Than One in 10 Americans 2Survey Reveals Paternity Questions Loom for More Than One in 10 Americans 3Cord Blood America Announces Exclusive Agreement With National Children's Leukemia Foundation to Store Stem Cells 2
(Date:11/18/2014)... , Nov. 17, 2014 The Parenteral Drug ... U.S. regulatory agencies will speak and at least seven more ... Conference at the Omni Shoreham Hotel in Washington ... once again to have significant support from the regulatory agencies ... Europe in our effort to help advance ...
(Date:11/11/2014)... , Nov. 11, 2014  Forensicon, Inc., a ... firm, is pleased to announce the promotion of ... Director of Digital Forensics. In Schiff,s new role as ... the team of digital forensics examiners and provide leadership ... Photo - http://photos.prnewswire.com/prnh/20141110/157719 ...
(Date:11/7/2014)... , November 6, 2014 Leading ... for better mobile security revolutionizing online transactions.  Companies in focus ... Holdings Ltd. (NYSE: BABA ), Google Inc. (NASDAQ: ... ), eBay Inc. (NASDAQ: EBAY ) and MasterCard ... NXTD and NXTDW), a biometric authentication company focused on ...
Breaking Biology News(10 mins):FDA's Janet Woodcock, EMA's Emer Cooke Headline PDA Quality Metrics Conference 2Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 2Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 3Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 4Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 5Universal Authentication Methods Provide More Secure Operations for Biometrics Devices - Company Joins FIDO Alliance for Consumer Protection 6
... ANU Vice-Chancellor, Professor Ian Young AO, has just published ... surf report. Research led by the Vice-Chancellor will ... at which ocean swells decay, or deteriorate, as they ... oil and gas production, and even recreational activities such ...
... recently awarded a $449,641 grant by the Institute of Museum ... crowd sourcing and gaming to support the enhancement of texts ... December 2013 and ends in December 2015. The Garden will ... Botanical Garden on the project. , The BHL is ...
... goes: "Don,t judge a book by its cover." Well, the ... are the most common and well-known of their kind ... might look similar to another, when you take a closer ... differences. In fact, a recently published study in the ...
Cached Biology News:VC predicts the motion of the ocean 2Missouri Botanical Garden aims to improve access to digital texts through online gaming 2Dolphin genetic study provides revelations 2
... Ribonuclease Inhibitors have broad spectrum RNase inhibitory ... of the neutral type (1). The 50kDa ... binding to RNases in a 1:1 ratio. ... RNasin Ribonuclease Inhibitor to RNase (e.g., RNase ...
UGT1A7 (E-15)...
... corresponding to the third cytoplasmic loop of ... to KLH. The immunizing peptide has 79% ... Physical form: Solution in phosphate buffered ... Titertest method: IHC (p). Titertest ...
... Human Pathogenic Viruses The ... (NCPV) preserves well characterised, authenticated ... secure facility, and NCPV is ... or nucleic acids derived from ...
Biology Products: