Navigation Links
Study puts troubling traits of H7N9 avian flu virus on display
Date:7/13/2013

MADISON, Wis. The emerging H7N9 avian influenza virus responsible for at least 37 deaths in China has qualities that could potentially spark a global outbreak of flu, according to a new study published today (July 10, 2013) in the journal Nature.

An international team led by Yoshihiro Kawaoka of the University of Wisconsin-Madison and the University of Tokyo conducted a comprehensive analysis of two of the first human isolates of the virus from patients in China. Their efforts revealed the H7N9 virus's ability to infect and replicate in several species of mammals, including ferrets and monkeys, and to transmit in ferrets data that suggests H7N9 viruses have the potential to become a worldwide threat to human health.

"H7N9 viruses have several features typically associated with human influenza viruses and therefore possess pandemic potential and need to be monitored closely," says Kawaoka, one of the world's leading experts on avian flu.

Normally, avian influenza viruses do not infect humans, with the exception of the highly pathogenic H5N1 strains. However, the H7N9 virus has so far infected at least 132 humans, killing more than 20 percent of those infected, and several instances of human-to-human infection are suspected.

The new study suggests that the ability of the H7N9 virus to infect and replicate in human cells may be due to just a few amino acid changes in the genetic sequence of the virus. "These two features are necessary, although not sufficient, to cause a pandemic," says Kawaoka, explaining that the influenza virus depends on host cells, which it hijacks to make new virus particles and sustain the chain of infection.

In monkeys, the H7N9 virus was shown to efficiently infect cells in both the upper and lower respiratory tract. Conventional human flu viruses are typically restricted to the upper airway of infected nonhuman primates.

"If H7N9 viruses acquire the ability to transmit ef
'/>"/>

Contact: Yoshihiro Kawaoka
kawaokay@svm.vetmed.wisc.edu
University of Wisconsin-Madison
Source:Eurekalert

Page: 1 2

Related biology technology :

1. DOs and DON’Ts of Study Start-Up: Best Practices to Improve Efficiency and Meet/Exceed Timelines, New Life Science Webinar Hosted by Xtalks
2. Study Scavenger and JALR.org Announce Alliance Utilizing Smart Phone Capabilities to Bring Clinical Trials to Motivated Subjects
3. New Approaches in Immunogenicity Assessment Using the New SQiDlite™ System: Case Study Analysis, New Life Science Webinar Hosted by Xtalks
4. New Study Reveals that PEEK Polymer Spinal Cage Is Superior to Titanium in Surgical Treatment of Multilevel Cervical Spondylotic Myelopathy
5. Americord Applauds Study on Stem Cell Therapy for Congenital Heart Defects
6. Study Data Tabulation Model in Real Time, New Webinar Hosted by Xtalks
7. RegeneCure Starts Clinical Study Using Polymeric Bone Stimulating Membrane for Dental Implants
8. Lilly and Incyte Announce Baricitinib Efficacy and Safety Data from the Open-Label, Long-Term Extension of the Phase 2b JADA Study in Patients with Rheumatoid Arthritis
9. Are Root Canals Headed for Obscurity? Stem Cell Study Indicates Maybe So
10. Adult Acne Treatment Explains a New Upcoming Study that may Change the Acne Treatment Industry
11. Ambit Announces Presentation of Results from Phase 2 ACE Study of Quizartinib in Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML) at the Annual Meeting of the American Society of Clinical Oncology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... May 28, 2015 ... has announced the addition of Jain ... Technologies, Markets and Companies"  to their ... report describes and evaluates animal biotechnology ... and pharmaceuticals as well as improvement ...
(Date:5/28/2015)... 27, 2015 Research and Markets( http://www.researchandmarkets.com/research/3nl6s2/neuroprotection ... new report "Neuroprotection - Drugs, Markets and ... report describes the role of neuroprotection in acute ... nervous system as well as in chronic diseases ... underlying mechanisms of damage to neural tissues are ...
(Date:5/28/2015)... DryLet, LLC a biotechnology company ... as animal waste reduction, bioremediation, wastewater treatment, aquaculture ... treatment plants and restaurant kitchen settings, announced today ... June 3-5 in Des Moines, Iowa. , ManureMagic™ ... Street Journal article because of its industry-leading qualities ...
(Date:5/28/2015)... Biscayne Pharmaceuticals, Inc ., today announced ... hormone-releasing hormone (GHRH) technology will be discussed in a ... The data show that the family of receptors for ... present on many primary breast cancer cells regardless of ... could have broad anti-cancer potential in breast cancer. 1 ...
Breaking Biology Technology:Global Animal Biotechnology Report 2015 - Technologies, Markets and Companies Analysis to 2024 2Global Animal Biotechnology Report 2015 - Technologies, Markets and Companies Analysis to 2024 3Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 2Global Neuroprotection Market Report 2015-2024 - Drugs, Markets and Companies 3DryLet to Showcase Patented ManureMagic™ at the 2015 World Pork Expo, June 3-5 in Des Moines, Iowa 2Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 2Data Presented At 2015 ASCO Annual Meeting Shows Biscayne Pharmaceuticals' GHRH Antagonist Target Is Expressed Across All Breast Cancer Subtypes 3
... Incorporated,(Nasdaq: SPEX ) reported a net loss for the three months ended March 31,2008 ... on the company,s on-going Phase 3 clinical trial,in the use of Naturlose for the treatment ... million and reflected the,start-up costs for the trial., , ... ...
... Vista Partners announced today that,it has initiated coverage on ... of Research of Vista Partners stated, "Synvista is one ... across. The,company is conducting four Phase 2 trials in ... a $100M market, could begin to,produce revenues as early ...
... Phase 1c Study Demonstrates Dose-dependent Activity of Antidote ... Biosciences today announced,the Journal of Thrombosis and Haemostasis, ... and Haemostasis, has published the,Phase 1c clinical results ... two-component system comprised of an aptamer-based anticoagulant,RB006, and ...
Cached Biology Technology:Spherix Reports 1st Quarter Earnings 2Vista Partners Initiates Coverage on Synvista Therapeutics, Inc. (AMEX: SYI) 2Regado Biosciences' REG1 Anticoagulation System Study Results Published in the Journal of Thrombosis and Haemostasis 2Regado Biosciences' REG1 Anticoagulation System Study Results Published in the Journal of Thrombosis and Haemostasis 3Regado Biosciences' REG1 Anticoagulation System Study Results Published in the Journal of Thrombosis and Haemostasis 4
(Date:5/14/2015)... , May 14, 2015  Verificient ... identity verification and online remote proctoring, announced ... software-as-a-service (SaaS) company and creator of the ... of the two companies will benefit from ... Canvas. As a fully integrated ...
(Date:5/10/2015)... -- Fingerprint Cards (FPC) has received an order ... distributor World Peace Industrial Group (WPI), part of WPG Holdings. ... . Deliveries are planned to take place during Q3 ... in China . The order value of ... + 1 000 MSEK for 2015.   Jörgen Lantto, ...
(Date:5/5/2015)... NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the "Company"), ... market, reminds investors and media that  Mr. David Tunnell ... SECURE CONNEXIONS AMERICA 2015, held in Washington DC ... conference is organized into a series of nine session tracks. ... Fraud: Where is the Trust in Cyberspace? and will ...
Breaking Biology News(10 mins):Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 235 Million 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 2NXT-ID, Inc.'s CTO, David Tunnell, Presents at CARTES SECURE CONNEXIONS AMERICA 2015 Today in Washington DC. 3
... 20, 2011Spas that offer massage therapy using fragrant essential ... harmful indoor air pollutants such as volatile organic compounds ... Environmental Engineering Science , a peer-reviewed journal published ... is available free online at www.liebertpub.com/ees ...
... the association for informatics professionals, honors four leaders ... to be presented during AMIA,s Annual Symposium, Oct. ... professionals to the Washington Hilton over the coming ... whose contributions to the health sector have had ...
... HEIDELBERG, GERMANY, 20 OCTOBER 2011 EMBO today acknowledges ... 14 countries by awarding them life-long EMBO membership. ... to research excellence and the exceptional achievements made by ... ranks of 1,500 of the best researchers in Europe ...
Cached Biology News:Can aromatherapy produce harmful indoor air pollutants? 2AMIA honors informatics professionals who are improving health, changing the world 2AMIA honors informatics professionals who are improving health, changing the world 346 outstanding life scientists elected to EMBO membership 2
...
Mouse H60 Allophycocyanin MAb (Clone 205326) ENTREZ GeneID: 15101...
Can be used for the quantitative recovery of small amounts of nucleic acids within dilute solutions. 5mg/ml...
Recombinant Mouse sTNF RII/TNFRSF1B...
Biology Products: