Navigation Links
Study Reaffirms Superiority of Trofile(TM) Assay
Date:12/19/2007

Pfizer Study Finds Pathway's SensiTrop(TM) Assay Is Discordant in Detecting

HIV Tropism with Clinically Validated Trofile

SOUTH SAN FRANCISCO, Calif., Dec. 19 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc. (Nasdaq: MGRM) today announced that Pfizer Inc (NYSE: PFE), the manufacturer of Selzentry(TM) (maraviroc), has reported the results of a study that compares Monogram's Trofile Assay and Pathway Diagnostics' SensiTrop Assay. Pfizer concluded, based on study results, that the SensiTrop results were discordant with the results obtained using Trofile, which was used and clinically validated in the Selzentry clinical trials.

In the study of 100 patient samples, of the 39 samples previously identified as dual/mixed (D/M) or X4-tropic by Trofile, 19 were classified as R5-tropic by SensiTrop. "This is of paramount importance," said William Young, Monogram's chief executive officer. In its release, Pfizer commented "these findings mean that there is a possibility that some patients whose tropism was assessed with SensiTrop may have received Selzentry based on an inaccurate R5 tropism reading. Selzentry is only indicated for use in treatment-experienced patients infected with R5-tropic HIV-1. If Selzentry is selected as an active drug for patients infected with D/M or X4-tropic HIV, it may not contribute to virologic suppression and could result in emergence of resistance to other drugs in the treatment regimen."

"We are delighted Pfizer undertook this comparative analysis with Trofile, which is the only clinically validated tropism assay," continued Young. "At Monogram, we believe strongly that scientific data should drive products and their use by physicians. All of our products are founded on science tha
'/>"/>

SOURCE Monogram Biosciences, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
3. Kline Study: Better Brushing Habits Boost European Oral Care Sales
4. Evotec to Present Details of the Positive Phase II Study in Insomnia With EVT 201 at the Worldsleep07 Congress in Cairns/Australia
5. NASA study will help stop stowaways to Mars
6. New Study Findings Confirm CLEXANE(R)/LOVENOX(R) Long-Term Clinical Benefit in Patients Suffering From Acute Coronary Syndrome
7. Study Published in Clinical Cancer Research Confirms Potential Of Peregrines Bavituximab Combined With Radiation In Lung Cancer
8. Evotec Reports Details of the Positive Proof-of-Concept Phase II Study in Insomnia With EVT 201
9. Study Supports Use of GlycoMark Blood Test to Evaluate Therapy in Children with Diabetes
10. Quigley Corporation Releases Update on Quigley Pharmas Phase IIb Clinical Study of QR-333 in Diabetic Peripheral Neuropathy
11. Biodel Inc. Announces VIAject(TM) Phase II Meal Study Data at the 2007 European Association for the Study of Diabetes Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2014)... (PRWEB) November 21, 2014 During his ... understood the need to surround himself with great people ... and entrepreneur, his friends often marveled at his extraordinarily ... lived his life and -- even with his death ... the Alzheimer’s disease that would ultimately take his life. ...
(Date:11/22/2014)... November 21, 2014 On November 17th ... the 2014 Emerging Medical Technologies Summit in San Francisco ... Widely regarded among Silicon Valley investors and technology ... innovation, the win also positions Briteseed to move ... competition in 2015 and compete with other elite innovation ...
(Date:11/22/2014)... November 21, 2014   ... Chief Commercial Officer zu KLOX    ... und Chief Financial Officer bestellt    ... Vermarktung seines jüngst zugelassenen Behandlungssystems zur Wundheilung zu beginnen ... das "Unternehmen") ist sehr erfreut, die folgenden personellen Veränderungen ...
(Date:11/21/2014)... Offering a complete line of laboratory ... promotion . The Sartorius Entris Balance is the perfect ... and easy-to-maintain balance entry level balance. , The Entris ... to help customer’s bridge the gap between a basic ... very durable. Sartorius is the second biggest balance manufacturer ...
Breaking Biology Technology:Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 2Insight Product Development Accelerator Member Wins MedTech Innovator Award Competition 3KLOX Technologies meldet Neubesetzung von Führungspositionen 2KLOX Technologies meldet Neubesetzung von Führungspositionen 3KLOX Technologies meldet Neubesetzung von Führungspositionen 4KLOX Technologies meldet Neubesetzung von Führungspositionen 5Pipette.com Announces an Extension on the Sartorius Entris Balance Promotion to the End of 2014 2
... The Global Probiotics Council,(GPC), a committee formed ... the availability of two grants for the second ... Each Young,Investigator Grant will provide $50,000 over one ... role of probiotics and gastrointestinal microbiota in health,and ...
... autoimmune disease,diagnostics market has demonstrated sustained growth due ... is occurring in the,market, promoting technology and product ... reimbursement policies for autoimmune diagnostic tests,persists, posing a ... (Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO ) ...
... is that it will dramatically outshine traditional computers in ... numbers, creating uncrackable codes and simulating the atomic structure ... if you,ll pardon the pun, has been taken by ... published in the journal Nature . Working in ...
Cached Biology Technology:New Young Investigator Grants for Probiotics Research Announced 2New Young Investigator Grants for Probiotics Research Announced 3New Young Investigator Grants for Probiotics Research Announced 4Advances in Detection Technology Drive the European Autoimmune Disease Diagnostics Market 2Advances in Detection Technology Drive the European Autoimmune Disease Diagnostics Market 3Stanford: Quantum computing spins closer 2
(Date:11/18/2014)...   News Highlights: ... The Partners Data Lake, an agile data and ... will allow researcher and clinicians to explore and ... lives of patients , The Partners Data ... the Partners system, breaking down physical barriers for ...
(Date:11/11/2014)... , Nov. 11, 2014  Forensicon, Inc., a ... firm, is pleased to announce the promotion of ... Director of Digital Forensics. In Schiff,s new role as ... the team of digital forensics examiners and provide leadership ... Photo - http://photos.prnewswire.com/prnh/20141110/157719 ...
(Date:11/6/2014)... TALLAHASSEE, Fla. -- A groundbreaking paper from a team ... better understanding of how plants could adapt to and ... The research, published in the latest issue of the ... how chromatin (the complex of DNA and proteins) is ... material, so that some genes are turned on and ...
Breaking Biology News(10 mins):Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 2Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 3Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 4Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 5Yaniv Schiff Promoted to Director of Digital Forensics at Forensicon, Inc. 2Maize analysis yields whole new world of genetic science 2
... have an explanation for how the most common strain ... rose to prominence. Research published in mBio , ... Microbiology, suggests that the strain recently acquired a number ... to grow and thrive on the skin where other ...
... WASHINGTONThe ancestor of snakes and lizards likely gave birth to ... have switched back and forth in their preferred reproductive mode, ... Dec. 17. "This is a very unusual and ... of thought," said Alex Pyron, Robert F. Griggs Assistant Professor ...
... Peterhans, a Roosevelt University professor and adjunct curator at ... mammals in Africa, has announced the discovery of four ... of the Democratic Republic of Congo. , The mammals ... led by the Wildlife Conservation Society (WCS) and in ...
Cached Biology News:MRSA strain gained dominance with help from skin bacteria 2Ancestor of snakes, lizards likely gave birth to live young 2Chicago scientist involved in discovery of 4 new mammal species in Democratic Republic of Congo 2
Mouse monoclonal [15-2] to Mannose Receptor (Biotin) ( Abpromise for all tested applications). entrezGeneID: 4360 SwissProtID: P22897...
Request Info...
Mouse monoclonal [DJR3] to DcR1 (Biotin) ( Abpromise for all tested applications). entrezGeneID: 8794 SwissProtID: O14798...
...
Biology Products: