Navigation Links
Study Links Biomechanics and Gene Expression in Stem Cells
Date:8/1/2014

Waterloo, ON (PRWEB) August 01, 2014

Testing the mechanical properties of microtissues by researchers has led to a better understanding embryonic development. How and why embryonic stem cells differentiate and reorganize into structurally and functionally distinct tissues is important because abnormalities can lead to devastating physical defects. Prof. Todd McDevitt, Melissa Kinney, and Rabbia Saeed worked from the premise that biophysical signals interact with biochemical cues to control many aspects of embryo development. In their recent study published in Nature Scientific Reports (http://www.nature.com/srep/2014/140306/srep04290/full/srep04290.html?WT.ec_id=SREP-631-20140311), the team assessed the mechanical changes in 3D stem cell microtissues and linked these changes with cell differentiation and tissue morphology changes.

The team used the CellScale MicroSquisher (http://www.cellscale.com/products/microsquisher) to perform mechanical testing of the 3D tissues, which were 200-500µm in size. The unique ability of the MicroSquisher to resolve small forces was critical for this application, where the peak forces were less than 20µN.

This data will enable a better understanding of embryonic development, which is critical developing strategies to prevent many birth defects. The data will also enable the development of new approaches to direct the differentiation and patterning of 3D microtissues for further research in drug development and tissue repair.

CellScale is an industry leader in providing researchers with precision biomaterial and mechanobiology test systems. Currently, you can find our products being used by world class academic and commercial organizations across the globe.

Our mechanical test systems are specifically designed for analyzing and characterizing the material properties of natural and artificial biomaterials.

Our mechanobiology technology helps advance research by providing insights into the response of cells to mechanical stimulation – a key factor in the pursuit of the next revolution in medical treatments.

Caleb Horst, Director of Business Development
CellScale Biomaterials Testing
519-342-6870

Read the full story at http://www.prweb.com/releases/2014/08/prweb12058650.htm.


'/>"/>
Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Related biology technology :

1. Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant
2. Selexis SA to Present New Data and a Case Study at IBC’s Cell Line Development and Engineering Conference
3. RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars
4. Zerenex (ferric citrate) long-term Phase 3 study results published in JASN
5. ORNL study reveals new characteristics of complex oxide surfaces
6. National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS
7. StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study
8. Syracuse University chemist to use NSF grant to study materials chemistry, nanoscience
9. Resolve Initiates Phase 2 Clinical Study in SLE
10. Research Study on Lithopone Industry (China, Global Regions) Development Trends Available at ReportsnReports.com
11. Worcester Polytechnic Institute Receives NIH Grant to Study Components of a Potentially Potent and Cost-Effective Malaria Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... , June 27, 2016  Global demand ... 4.6 percent through 2020 to $7.2 billion.  This ... and beverages, cleaning products, biofuel production, animal feed, ... biotechnology, diagnostics, and biocatalysts). Food and beverages will ... driven by increasing consumption of products containing enzymes ...
(Date:6/27/2016)... ... 2016 , ... Parallel 6 , the leading software as a service ... Virtual Patient Encounter CONSULT module which enables both audio and video telemedicine communication ... , Using the CONSULT module, patients and physicians can schedule a face to face ...
(Date:6/27/2016)...   Ginkgo Bioworks , a leading organism ... today awarded as one of the World Economic ... most innovative companies. Ginkgo Bioworks is engineering biology ... world in the nutrition, health and consumer goods ... customers including Fortune 500 companies to design microbes ...
(Date:6/24/2016)... ... ... Researchers at the Universita Politecnica delle Marche in Ancona combed medical journal articles ... findings are the subject of a new article on the Surviving Mesothelioma website. ... blood, lung fluid or tissue of mesothelioma patients that can help point doctors to ...
Breaking Biology Technology:
(Date:5/20/2016)... , May 20, 2016  VoiceIt is ... partnership with VoicePass. By working together, ... experience.  Because VoiceIt and VoicePass take slightly different ... engines increases both security and usability. ... excitement about this new partnership. "This ...
(Date:5/9/2016)... -- Elevay is currently known as the ... high net worth professionals seeking travel for work   ... there is still no substitute for a face-to-face meeting. ... deal with a firm handshake. This is why wealthy ... citizenship via investment programs like those offered by the ...
(Date:4/28/2016)... First quarter 2016:   , Revenues amounted ... quarter of 2015 The gross margin was 49% (27) ... the operating margin was 40% (-13) Earnings per share ... operations was SEK 249.9 M (21.2) , Outlook   ... M. The operating margin for 2016 is estimated to ...
Breaking Biology News(10 mins):