Navigation Links
Study Links Biomechanics and Gene Expression in Stem Cells
Date:8/1/2014

Waterloo, ON (PRWEB) August 01, 2014

Testing the mechanical properties of microtissues by researchers has led to a better understanding embryonic development. How and why embryonic stem cells differentiate and reorganize into structurally and functionally distinct tissues is important because abnormalities can lead to devastating physical defects. Prof. Todd McDevitt, Melissa Kinney, and Rabbia Saeed worked from the premise that biophysical signals interact with biochemical cues to control many aspects of embryo development. In their recent study published in Nature Scientific Reports (http://www.nature.com/srep/2014/140306/srep04290/full/srep04290.html?WT.ec_id=SREP-631-20140311), the team assessed the mechanical changes in 3D stem cell microtissues and linked these changes with cell differentiation and tissue morphology changes.

The team used the CellScale MicroSquisher (http://www.cellscale.com/products/microsquisher) to perform mechanical testing of the 3D tissues, which were 200-500µm in size. The unique ability of the MicroSquisher to resolve small forces was critical for this application, where the peak forces were less than 20µN.

This data will enable a better understanding of embryonic development, which is critical developing strategies to prevent many birth defects. The data will also enable the development of new approaches to direct the differentiation and patterning of 3D microtissues for further research in drug development and tissue repair.

CellScale is an industry leader in providing researchers with precision biomaterial and mechanobiology test systems. Currently, you can find our products being used by world class academic and commercial organizations across the globe.

Our mechanical test systems are specifically designed for analyzing and characterizing the material properties of natural and artificial biomaterials.

Our mechanobiology technology helps advance research by providing insights into the response of cells to mechanical stimulation – a key factor in the pursuit of the next revolution in medical treatments.

Caleb Horst, Director of Business Development
CellScale Biomaterials Testing
519-342-6870

Read the full story at http://www.prweb.com/releases/2014/08/prweb12058650.htm.


'/>"/>
Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Related biology technology :

1. Study Suggests C1-INH May Aid in Prevention of Antibody-Mediated Rejection Following Kidney Transplant
2. Selexis SA to Present New Data and a Case Study at IBC’s Cell Line Development and Engineering Conference
3. RXi Pharmaceuticals Expands Clinical Program with Initiation of Third Phase 2a Study with RXI-109 for Treatment of Hypertrophic Scars
4. Zerenex (ferric citrate) long-term Phase 3 study results published in JASN
5. ORNL study reveals new characteristics of complex oxide surfaces
6. National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS
7. StemGenex® Gives Hope to Parkinson’s Patients through New Stem Cell Clinical Study
8. Syracuse University chemist to use NSF grant to study materials chemistry, nanoscience
9. Resolve Initiates Phase 2 Clinical Study in SLE
10. Research Study on Lithopone Industry (China, Global Regions) Development Trends Available at ReportsnReports.com
11. Worcester Polytechnic Institute Receives NIH Grant to Study Components of a Potentially Potent and Cost-Effective Malaria Treatment
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/27/2017)...  Pendant Biosciences, Inc. (formerly Nanoferix, Inc.), a privately-held ... delivery technologies, today announced that it has been accepted ... Toronto . Shawn Glinter , ... "We are excited to become part of the JLABS ... honored to be the first Tennessee ...
(Date:4/26/2017)... ... April 26, 2017 , ... Looking for gift ideas ... events company, offers one-of-a-kind gifts, ranging from gourmet cooking experiences to Farmer’s Market ... guests leave inspired with new cooking tips and techniques, thanks to Chef Jodi ...
(Date:4/26/2017)... ... April 26, 2017 , ... Led by ex-FDA official Peggy ... comes to Tampa, San Francisco and Boston in 2017. The 2016 sold-out ... such as Pfizer Inc., Teva Pharmaceuticals, Advaxis, Inc., Ocular Therapeutix Inc., Cell Culture ...
(Date:4/26/2017)... ... 26, 2017 , ... Baltimore bio tech firm, PathSensors, Inc., ... solution at the National Postal Forum 2017 in Baltimore, Maryland, May 21st through ... easy to use and low cost threat detection solution for government and commercial ...
Breaking Biology Technology:
(Date:4/19/2017)... ALBANY, New York , April 19, 2017 /PRNewswire/ ... highly competitive, as its vendor landscape is marked by ... in the market is however held by five major ... and Safran. Together these companies accounted for nearly 61% ... majority of the leading companies in the global military ...
(Date:4/13/2017)... , April 13, 2017 According to a ... Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication Type, Deployment ... the IAM Market is expected to grow from USD 14.30 Billion in ... Rate (CAGR) of 17.3%. ... MarketsandMarkets Logo ...
(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
Breaking Biology News(10 mins):