Navigation Links
Study From the University of Texas M.D. Anderson Cancer Center Demonstrates That AHCC(R) is Safe in Combination With Most Chemotherapeutic Agents
Date:11/6/2008

Supports safety of AHCC for cancer patients undergoing chemotherapy

PURCHASE, N.Y., Nov. 6 /PRNewswire/ -- A recently published study in the Journal of the Society for Integrative Oncology (Vol. 6, No. 3 (Summer), 2008: pp 105-109) by researchers at the University of Texas M.D. Anderson Cancer Center with the support of researchers from Amino Up Chemical Company in Sapporo, Japan has demonstrated that AHCC (Active Hexose Correlated Compound) can be safely used in combination with most chemotherapy agents. AHCC is a leading and commonly utilized dietary supplement for immune enhancement and cancer. The study was designed to determine on how AHCC interacts with select chemotherapy agents. As most chemotherapy agents undergo metabolism in the body through the CYP450 (Cytochrome P-450) pathway, this parameter was investigated in combination with four isoenzymes (3A4, 2C8, 2C9 and 2D6). This was followed by an evaluation of AHCC by including it as a substrate of these same isoenzymes.

The results of this in vitro metabolism study indicated that AHCC is not an inhibitor of the major CYP450 isoenzyme pathways. Therefore, AHCC is safe and unlikely to result in increased toxicity when used in combination with commonly used chemotherapeutic agents such as Cyclophosphamide, Ifosfamide, Paclitaxel, Docetaxel, Irinotecan, Vincristine, Interferon and Imatinib. It was demonstrated, that AHCC may have the potential for induce metabolism of drugs metabolized via the CYP450 2D6 pathway. Fortunately, the CYP450 2D6 is not a predominant pathway for metabolism of the most commonly used chemotherapy agents.

"Research shows that AHCC benefits cancer patients with its antitumor effects as well as its potential restorative effects on natural killer cells, macrophages and cytokines after anticancer chemotherapy," said Judith Smith, Pharm.D., BCOP,FCCP, FISOPP, Department of Gynecologic Oncology, Division of Surgery with The University of Texas M.D. Anderson Canc
'/>"/>

SOURCE AHCC Research Association
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Morria Biopharmaceuticals Plc Announces Positive Clinical Results for MRX-4 in its Phase II Clinical Study in Allergic Rhinitis Patients
2. New Study Provides Key Findings for Biopharma Product Launch Evaluation
3. Top-Line Preliminary Data From Phase II/III Study of Cortheras Relaxin in Acute Heart Failure to be Presented in Satellite Symposium at AHA Scientific Sessions 2008
4. DermTech and Rady Childrens Hospital-San Diego, Initiate Study to Understand Effects of Vitamin D as a Treatment for Atopic Dermatitis in Children and Young Adults
5. One-Year Data Show Golimumab Improved Signs and Symptoms In Patients with Psoriatic Arthritis In Phase 3 Study
6. Positive Study Results for Ceftaroline Phase III Clinical Study for the Treatment of Complicated Skin and Skin Structure Infections Presented at ICAAC / IDSA
7. BioCryst Reports Results From the First-Ever Completed Active-Controlled Phase 2 Study in Hospitalized Influenza
8. Large-scale genetic study sheds new light on lung cancer
9. PARI Respiratory to Present New Study Comparing Nebulizers Delivering Budesonide at CHEST 2008
10. Independent Study Reveals SYNVISC(R) Offers Longer Knee Pain Relief and Greater Patient Satisfaction for Those Suffering from Osteoarthritis of the Knee
11. Clinical Study of Intermezzo(R) for the Treatment of Middle of the Night Awakening Published in SLEEP
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... 14, 2014 Date: Friday, April 11, 2014 ... Country Club, 1360 Almshouse Road, Warrington, Pa. , ... solely dedicated to finding a cure for hepatitis B and ... host its annual Crystal Ball on Friday, April 11 at ...
(Date:1/14/2014)... , Jan. 14, 2014 As pet owners drew up their ... of them wrote: "Take better care of my furry companion." Nowadays ... clothes and top-brand carrying cases to take the little canine or ... also feel compelled to buy some pricey toys at the pet ...
(Date:1/14/2014)... January 14, 2014 iLab Solutions, the leader ... the new Director of Product Strategy. In this role, Michelle ... iLab sub-teams to guide in the development of iLab products. ... the maximum possible benefit to the scientific community by offering ...
(Date:1/14/2014)... ®, provider of RapidResponse ®, a cloud-based supply chain ... S&OP ) service, is proud to be a gold sponsor ... at the Hilton San Diego Bayfront, January 30 – 31, ... , Director of Supply Chain at Amgen, as she presents ...
Breaking Biology Technology:Hepatitis B Foundation to Host Annual Crystal Ball Gala 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2iLab Solutions Announces Michelle Detwiler as the New Director of Product Strategy 2Event Alert: Kinaxis Customer to Present at the Biomanufacturing Summit "Supply Chain: Improving Network Effectiveness" 2
... and MTA: CTIC) today announced that a single institutional ... 15% Convertible,Senior Notes due 2011, with an initial conversion ... approximately 14.6 million shares of common stock,with an exercise ... a partial exercise of a previously granted,warrant right for ...
... of 14% ... 2009 Revenue Guidance, HOUSTON, June 11 Cyberonics, Inc. (Nasdaq:,CYBX) today ... Key quarterly highlights, Key results for the fourth quarter of ... -- Net sales of $33.9 million, an 8% increase from $31.4 million. ...
... Renewable Natural Gas ... and Other Waste Products, TARRYTOWN, N.Y., June 11 ... in the renewable bioenergy industry,will today mark the commencement ... a ground breaking ceremony. The Dublin, Texas,facility, owned and ...
Cached Biology Technology:Cell Therapeutics, Inc. Announces Issuance of 2011 Convertible Senior Notes and Common Stock Warrants to a Single Institutional Investor 2Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 2Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 3Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 4Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 5Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 6Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 7Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 8Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 9Cyberonics Reports Strong Revenue Growth and Profitability in Fiscal 2008 Fourth Quarter 10Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 2Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 3Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 4Environmental Power Holds Ground Breaking Ceremony for Renewable Natural Gas Facility at Rio Leche Estates 5
(Date:4/17/2014)... Gauthier and Professor Luca Razzari of the nergie ... large grants from the John R. Evans Leaders ... for the acquisition of state-of-the-art biotech and nanophotonics ... grants from the Ministre de l,Enseignement suprieur, de ... Technologie (MESRST). These new laboratories will help us ...
(Date:4/17/2014)... news release is available in German . ... us to recognise objects; they also provide us with a ... run, turn around, fall or sit still in a car ... motion trace on our retinas. Seemingly without effort, our brain ... maintain a stable position and a steady gaze during our ...
(Date:4/17/2014)... One day about eight years ago, Katia Silvera ... and her father were on a field trip in a ... orchid they had never seen before. , Unable to identify ... The orchid turned out to be an unnamed species. ... silverarum . , "Lophiaris" is the genus name, comprising about ...
Breaking Biology News(10 mins):New state-of-the-art biotech and nanotech equipment for INRS 2How vision makes sure that little fish do not get carried away 2How vision makes sure that little fish do not get carried away 3How vision makes sure that little fish do not get carried away 4Orchid named after UC Riverside researcher 2Orchid named after UC Riverside researcher 3
... a gene required for stem cells in the brain to ... neuroblastoma, a deadly childhood cancer of the nervous system, according ... Cell today, the findings also provide clues about how ... Neuroblastoma can appear in nervous tissue in the abdomen, chest ...
... August 12, 2013 - Elsevier, a world-leading provider of ... pleased to announce the launch of Video Journal ... an open access video journal providing scientists and ... and step-by-step demonstrations and the first of its kind ...
... (BMI) appears to be stronger in adults without diabetes than ... Journal of General Internal Medicine in a study ... and colleagues. The researchers suggest that studies on body weight ... status in the population. In their analysis, Jackson,s ...
Cached Biology News:New insights into neuroblastoma tumor suppressor may provide clues for improved treatment 2Elsevier launches first video journal in gastrointestinal endoscopy 2Obesity and mortality association differs between individuals with and without diabetes 2
... are cytopathic effect inhibition assays, also known as ... tissue culture supernatents; serum from PK studies and ... is defined as the quantity of interferon required ... viral infection by 50%. All standards ...
Request Info...
...
...
Biology Products: