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Stemline Therapeutics, Inc. Announces Two Poster Presentations of SL-401 Efficacy Data Against Lymphoid Cancers at the 53rd Annual Meeting of the American Society of Hematology (ASH)
Date:12/8/2011

ion are as follows: The IL-3Ralpha-Targeted Drug SL-401 Selectively Kills Blastic Plasmacytoid Dendritic Cell Neoplasm CellsAbstract #: 2588Lead Author:  Fanny Angelot-Delettre, PhD, Institut National de la Sante et de la Recherche MedicaleSession: 614. Acute Lymphoblastic Leukemia - Therapy, excluding Transplantation: Poster IIDate/Time: Sunday, December 11, 2011; 6:00 - 8:00pm PTLocation: Hall GH (San Diego Convention Center) Hodgkin's Lymphoma Cell Lines Have Up-Regulated IL-3 Receptor alpha (IL-3Ralpha) Expression and Are Sensitive to SL-401, An IL-3Ralpha-Targeted Drug Abstract #: 3737Lead Author: Catherine Diefenbach, MD, New York University Cancer InstituteSession: 625. Lymphoma - Pre-Clinical - Chemotherapy and Biologic Agents: Poster IIIDate/Time: Monday, December 12, 2011; 6:00 - 8:00pm PTLocation: Hall GH (San Diego Convention Center) A copy of the above referenced abstracts can be viewed online through the ASH website at www.hematology.org.

About SL-401

SL-401 is a novel clinically active oncology compound that targets the interleukin-3 receptor (IL-3R). IL-3R is overexpressed on cancer stem cells (CSCs) and tumor bulk of multiple hematologic cancers. In a Phase I/II trial of patients with advanced acute myeloid leukemia (AML), SL-401 demonstrated single agent efficacy, including complete responses (CRs) and an overall survival benefit, in heavily pretreated patients. In addition, SL-401 was well-tolerated and was not toxic to the bone marrow. Given these promising results, SL-401 is being advanced into later stage trials in this indication. SL-401 is also being clinically tested in Phase I/II studies of patients with high risk myelodysplastic syndrome (MDS) and advanced chronic myeloid leukemia (CML). SL-401 was granted Orphan Drug Designation by the FDA for the treatment of AML.

About Stemline Therapeutics, Inc.Stemline Therapeutics, Inc. is a clinical stage biopharmac
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