Navigation Links
Stem cells produce compact, regenerated bone in mandible transplants
Date:3/15/2013

Durham, NC (PRWEB) March 15, 2013

Bone transplantation is a major strategy for the repair of bone defects. However, reconstruction of the mandible (jawbone) has long been a difficult challenge for oral surgeons — at least up to now. A new study in the latest issue of STEM CELLS Translational Medicine shows how stem cells can be used to successfully repair the mandible after a molar extraction and, years later, the new bone is still functioning properly.

Interestingly, the regenerated bone is also hard, rather than the spongy kind normally found in the jaw.

The new study is a follow-up to previous investigations by an international team of researchers in which they discovered that mesenchymal stem cells taken from dental pulp and seeded on a collagen scaffold successfully repaired the mandible bone. In this latest work, they checked on patients who had received the mandible bone grafts three years earlier to assess the stability and quality of the regenerated bone and vessel network.

They found the new bone had normal function and was richly vascularized, although was much more compact than the spongy type normally found in the mandible. The team theorized that, most probably, regeneration of compact bone occurs because grafted dental-pulp stem cells do not follow the local signals of the surrounding spongy bone.

“The mandible is constructed from spongey bone on account of its role linked to the presence of teeth and their movements, so regeneration of a compact, rather than a spongy bone type, is difficult to justify physiologically. We concluded, therefore, that grafted dental pulp stem cells do not pursue the local environmental signals emanating from the alveolar bone surrounding the graft site,” said Gianpaolo Papaccio, M.D., Ph.D., of the Department of Experimental Medicine at Second University of Naples, Naples, Italy. He led the study team that included colleagues from Second University
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

0

GOOD

Page: 1 2 3

Related biology technology :

1. New method for producing precursor of neurons, bone and other important tissues from stem cells
2. Biocept and Academic Collaborators to Present Posters at San Antonio Breast Cancer Symposium on Circulating Tumor Cells (CTCs)
3. Notre Dame researchers develop paint-on solar cells
4. Cord Blood America Announces Exclusive Agreement With National Childrens Leukemia Foundation to Store Stem Cells
5. Stem Cells: Worldwide Markets for Transplantation, Cord Blood Banking and Drug Development
6. In solar cells, tweaking the tiniest of parts yields big jump in efficiency
7. Mesenchymal Stem Cells Have New Cell Culture Environment
8. Discovery in Nature elucidates immune cells in skin and supports novel vaccine approach
9. Scientists Discover How a Bacterial Pathogen Breaks Down Barriers to Enter and Infect Cells
10. IntelliCell BioSciences Signs Technology Licensing Agreement with Stem Cells 21 Thailand
11. Study dusts sugar coating off little-known regulation in cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... The New Jersey chapter of the largest organization ... (BDPA), is hosting its 10th annual Families in Technology ... will encourage students and their parents to explore the ... many of the industries’ finest teachers. Held from 9 ... of Technology, the event will include workshops, instruction and ...
(Date:5/23/2013)... May 23, 2013 During the ... critical to adhere to principles of good clinical ... Esteemed speaker Dr. Jeremy Lim, Fellow, Clinical Development ... ,     Understand the International Conference on ... and additional regulations for the conduction of clinical ...
(Date:5/23/2013)... Washington, DC (PRWEB) May 23, 2013 ... of genetics-based ancestry tracing for people of African ... myDNAmix Admixture product offering. For people of all ... genetic make-up from five distinct populations: Indigenous Americas ... Europe and India Subcontinent. , Originally ...
(Date:5/23/2013)... St. Louis, Missouri (PRWEB) May 23, 2013 ... design and manufacture of complete thermal systems, recently ... more than 90 years of experience in designing ... most complete selection of products to serve diverse ... lead-time options is featured at the beginning of ...
Breaking Biology Technology:Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2Adhering to Good Clinical Practice, New Webinar Hosted by Xtalks 2AfricanAncestry.com Rolls Out Improved MyDNAMix Admixture Test for People of all Races; Enhancements Increase Accuracy in Estimation of Ancestral Makeup 2AfricanAncestry.com Rolls Out Improved MyDNAMix Admixture Test for People of all Races; Enhancements Increase Accuracy in Estimation of Ancestral Makeup 3Watlow Introduces Its New Industrial Heater Catalog 2
... world is a very different place out beyond the horizon. ... large cargo ships plying the worlds waterways and oceans, not ... out of ports, loading, unloading, changing out crews and cargos, ... , , In what can be a very murky world ...
... differences among countries. This is what medical researchers ... from biobanks in their research. For one thing, ... international studies. In the latest issue of Nature ... (CBE), together with leading biobank researchers, put forward a ...
... interest in the health-associated properties of probiotics, also ... the food needed for the growth of probiotic ... have discovered a natural fruit-based extract that dramatically ... bacteria such as the lactic acid bacteria, which ...
Cached Biology Technology:Out beyond the horizon 2Out beyond the horizon 3Long-awaited international ethical guidelines for biobank researchers 2University of Leicester scientists discover technique to help 'friendly bacteria' 2
(Date:5/22/2013)... for prostate cancer could become as easy for men ... UC Irvine research published today in the Journal ... than a decade of work, UC Irvine chemists have ... for prostate cancer in urine, meaning that the disease ... at dramatically lower cost. The same technology could potentially ...
(Date:5/21/2013)... NC Biologists have known for a long time ... why isn,t well understood, particularly for plants. But it ... Lanfear of Australian National University and the U. S. ... to be published 21 May in the journal ... plants have faster-changing genomes. , Drawing from a database ...
(Date:5/21/2013)... Wash. A new analysis shows that the nation,s ... of enough algae to produce up to 25 billion ... States, one-twelfth of the country,s yearly needs. , The ... resources that would be needed to grow significant amounts ... results were published in the May 7 issue of ...
Breaking Biology News(10 mins):UCI chemists devise inexpensive, accurate way to detect prostate cancer 2UCI chemists devise inexpensive, accurate way to detect prostate cancer 3Small but speedy: Short plants live in the evolutionary fast lane 2Going green: Nation equipped to grow serious amounts of pond scum for fuel 2Going green: Nation equipped to grow serious amounts of pond scum for fuel 3Going green: Nation equipped to grow serious amounts of pond scum for fuel 4
... discovered that roots of a plant used a century ago ... effects in laboratory experiments in killing the H1N1 swine flu ... pleasant onion-like taste when cooked, but when raw it has ... the Devil" plant. Their report is scheduled for the Sept. ...
... if your child had a fever or be certain ... you would, of course, use a thermometer that you ... its range. However, it isn,t that simple for researchers ... devices used in medical diagnostics, DNA forensics and "lab-on-a-chip" ...
... The latest data from groundbreaking human clinical trials of ... primary determinant of improvements in achieving better diabetes control is ... more rather than the age of patients, and that ... 1 diabetes begin using the devices including experiencing fewer ...
Cached Biology News:NIST calculations may improve temperature measures for microfluidics 2JDRF-funded studies show regular CGM use increases diabetes control for all age groups 2JDRF-funded studies show regular CGM use increases diabetes control for all age groups 3JDRF-funded studies show regular CGM use increases diabetes control for all age groups 4JDRF-funded studies show regular CGM use increases diabetes control for all age groups 5
... fermentation systems for cultivation of microorganisms and ... of bio-pharmaceutical products maximum performance and economy ... and cell fermentation 10 L 1,500 ... ,*Fully automated control system ,*High-quality ...
tracking dye in electrophoresis; free acid, C 19 H 10 BrO 5 S; MW: 669.96...
... Magnetofection technology, SilenceMag is the most ... rapid and easy to use, SilenceMag ... Specifically designed for siRNA delivery, SilenceMag ... low doses of siRNA.,SilenceMag formulation gives ...
... technology, SilenceMag is the most efficient ... and easy to use, SilenceMag is ... designed for siRNA delivery, SilenceMag allows ... doses of siRNA.,SilenceMag formulation gives reliable ...
Biology Products: