Navigation Links
Stem Cell Transplantation Research at The Cancer Center at Hackensack University Medical Center Aims to Develop 'Designer' Transplants
Date:7/23/2008

HACKENSACK, N.J., July 16 /PRNewswire/ --- Over the past two decades, stem cell transplantation has evolved from being an experimental treatment to one that is a viable option for patients with hematologic (blood) malignancies and other life-threatening blood disorders. Researchers and clinicians at the Adult Blood and Marrow Stem Cell Transplantation Program at The Cancer Center at Hackensack University Medical Center are responsible for many of the innovations and techniques used in today's successful transplants.

Stem cell transplantation researchers in The Cancer Center's Division of Research recently published results of a study in Blood, the scientific journal of the American Society of Hematology, that may take physicians one step closer to performing customized "designer" stem cell transplants that could lead to better treatment outcomes for patients.

The paper, "Overlap Between in vitro Donor Anti-Host and in vivo Post Transplantation T Cell Response Vß Utilization: A New Paradigm for Designer Allogeneic Blood and Marrow Transplantation," was co-authored by Cancer Center researchers Thea Friedman, Ph.D., director of laboratory research; Robert Korngold, Ph.D., chief of the Division of Research; Michele L. Donato, M.D., director of the Blood and Marrow Collection Facility; and Scott D. Rowley, M.D., chief of the Division of Blood and Marrow Stem Cell Transplantation; and researchers from the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia. The paper confirms that a technique - called Vß (beta) spectratype analysis - can be used to identify mature donor T cells (disease-fighting white blood cells) that can be harmful to the patient.

One of the major risks of an allogeneic transplant (one that uses stem cells removed from a donor) is graft-versus-host disease (GVHD). GVHD is a potentially fatal complication that can occur when mature donor T cells that are transferred along with stem cells from donated blood or b
'/>"/>

SOURCE The Cancer Center
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Investigational Studies Highlight Potential Utility of Zevalin(R) (Ibritumomab Tiuxetan) Radioimmunotherapy in Stem Cell Transplantation for Non-Hodgkins Lymphoma
2. DARPA awards research team $1.2M grant to study surface enhanced Raman scattering
3. Argonne researchers win 2 R&D 100 Awards
4. AMT Starts Collaboration With St. Jude Childrens Research Hospital on Gene Therapy for Hemophilia B. Company Accesses Exclusive Commercial Rights to Final Therapy
5. Worldwide Clinical Trials Emerges as Leading Global Contract Research Organization
6. Sangamo BioSciences and Sigma-Aldrich Announce Research and License Agreement With Roche for the Use of ZFN Technology for Generation of Transgenic Animals
7. Research helps understand factors that influence efficiency of organic-based devices
8. Telik Announces Publication of Diabetes Research in Bioorganic & Medicinal Chemistry Letters
9. Ferring Research Infertility and Gynaecology GrAnt (FRIGGA) 2008 Winners Announced
10. Eniva VIBE(R) Nutraceutical Tested at Linus Pauling Micronutrient Research Institute and Found to Possess DNA Protective Properties
11. Albany College of Pharmacy Researcher Receives $368,445 Grant from the National Institutes of Health
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/1/2008)... Isis Pharmaceuticals,I...ast: , , What: New findings published in ...icroRNA, known as miR-21, in heart failure, .../ 5:30 a.m. PT, Where: http://www.isispharm... log onto our website listed above., , I...
(Date:12/1/2008)...Newswire-FirstCall/ -- , - For Effective Li..., EMBASE(R), Elsevier,s biomedical and pharm...nnounced that it has partnered with QUOSA(TM) to e... full text of EMBASE.com search,results via a new...tion,Manager. , QUOSA Information Manager ...
(Date:11/28/2008)...wswire-FirstCall/ -- Encorium Group, Inc.,(Nasdaq...research organization,(CRO) conducting studies in...,pharmaceutical and biotechnology companies, toda...d a letter from Nasdaq stating that since it had n...ded September 30, 2008 as of the,date of the lett...
(Date:11/28/2008)...8 Why Humans Age is the title o...rdi, co-founder and formulator of Longevinex(R) (l...o promote healthy aging. , , To view the M...newswire.com/mnr/longevinex/35829/ , , The...f aging -- that humans begin to age biologically o...
Breaking Biology Technology:Elsevier's EMBASE.com Partners With QUOSA 2Elsevier's EMBASE.com Partners With QUOSA 3Elsevier's EMBASE.com Partners With QUOSA 4Encorium Announces Receipt of Letter from Nasdaq Regarding its Third Quarter 2008 Form 10-Q Filing 2Encorium Announces Receipt of Letter from Nasdaq Regarding its Third Quarter 2008 Form 10-Q Filing 3Video: 8-Minute Film Documentary Explores Why Humans Age 2
... Removal Kit , , D... from blood total RNA with a simple magnetic ...treatments) , Increases s...in microarray profiling experiments , ...ood , Kit and MessageAmp II aRN...
... , , , The flas... easiest, and most consistent method for PAGE puri...raditional Polyacrylamide Gel Electrophoresis (PAG...ion of small nucleic acids, the flashPAGE , ... the purification of RNA , and DNA. , ...
... Removes trace quantities of DNA that , ...se enhancer increases the potency of TURBO DNase b... , Remove DNase from RNA solutions in...heating , , TURBO DNase i... The Best Way to Remove Contaminating , ...
...n the strength of , RNA later... specimens during sample collection or shippi...b or out in the field, this aqueous, non-toxic ,...ion Solution functions from , a...ot of how , researchers have us...
Other Biology Technology:Unmask Blood RNA for Gene Expression Profiling 2Unmask Blood RNA for Gene Expression Profiling 3Unmask Blood RNA for Gene Expression Profiling 4Ultra-Fast Purification of Small Nucleic Acids 2Ultra-Fast Purification of Small Nucleic Acids 3Ultra-Fast Purification of Small Nucleic Acids 4Ultra-Fast Purification of Small Nucleic Acids 5The World's Best DNase Improved TURBO DNA-free 2The World's Best DNase Improved TURBO DNA-free 3The World's Best DNase Improved TURBO DNA-free 4The World's Best DNase Improved TURBO DNA-free 5RNAlater Around the World: The Art of Processing Difficult Samples 2RNAlater Around the World: The Art of Processing Difficult Samples 3
(Date:12/1/2008)...der, CO, USA The December Geosphere , The Geolog.... Topics include detailed data integration from mu...sedimentology, and paleontology, to study the sout...llion years ago; sedimentation in a piggyback basi...ge, Nevada; and a study of the South Balkan extens...
(Date:12/1/2008)...OVIDENCE, R.I. [Brown University] Gray mold is a ...s scientific name Botrytis cinerea , is a scourge...t species, including staples such as tomatoes, str...nd endive, peas, peppers, and potatoes. Gray mold ... toxin that poisons the host plants, cells, eventu...
(Date:12/1/2008)...AGO The December issue of the Journal of the Ame...ies focusing on the everyday eating habits of cons... to be a popular meal choice and methods for addin... published in the December 2008 Journal of the Am...t Fast-Food Restaurants: Reported Reasons among Fr...
(Date:12/1/2008)...en (Belgium), Stockholm (Sweden) Permission has b...lity trial on patients for a remedy for ALS. ALS i...der that strikes 5 persons in every 100,000. The d... active period of their lives − without warn...reviously shown the possibilities for the use of V...
Breaking Biology News(10 mins):December Geosphere media highlights 2December Geosphere media highlights 3Brown chemist finds gray mold's killer gene 2News from the December 2008 Journal of the American Dietetic Association 2First trial in patients with a potential treatment of the incurable ALS muscle disease 2First trial in patients with a potential treatment of the incurable ALS muscle disease 3Smoking belies milder disease but worse prognosis for IPF patients 9546 1Smoking belies milder disease but worse prognosis for IPF patients 9546 2Tri State Hospital to Gain Greater Efficiency and Responsiveness in Delivering Patient Care with Siemens Open Communications Solutions 9541 1Tri State Hospital to Gain Greater Efficiency and Responsiveness in Delivering Patient Care with Siemens Open Communications Solutions 9541 2Tri State Hospital to Gain Greater Efficiency and Responsiveness in Delivering Patient Care with Siemens Open Communications Solutions 9541 3Tri State Hospital to Gain Greater Efficiency and Responsiveness in Delivering Patient Care with Siemens Open Communications Solutions 9541 4Tri State Hospital to Gain Greater Efficiency and Responsiveness in Delivering Patient Care with Siemens Open Communications Solutions 9541 5Cell Therapeutics Inc 28CTI 29 Prices 241 27 million 28euros 856 000 29 Offering of Common Stock through Societe Generale 2589 1Cell Therapeutics Inc 28CTI 29 Prices 241 27 million 28euros 856 000 29 Offering of Common Stock through Societe Generale 2589 2Hormonal dietary supplements might promote prostate cancer progression 9535 1Hormonal dietary supplements might promote prostate cancer progression 9535 2Hormonal dietary supplements might promote prostate cancer progression 9535 3
...esearchers at Rensselaer Polytechnic Institute wil...al science with the help of IBM,s Blue Gene superc...earch (SUR) program, this Blue Gene will complemen... IBM, and New York state to create one of the worl...centers. , The equipment will provide a resource f...
...orking with dogs and using the latest in imaging s... scanner, Johns Hopkins heart specialists have dev... that has been slowed down by narrowing of the cor... than half the time of exercise stress tests and ...ng of vessels more likely to become blocked and ca...
...he discovery of a 100-million-year old bee embedde... "pushes the bee fossil record back about 35 milli...sociate professor of entomology. , Danforth and Ge...ee embedded in amber from a mine in northern Myanm...scovery, which the researchers say supports a new ...
...njecting performance enhancing corticosteroid horm...nd tests exist that can detect injected hormones. ...produce extra amounts of its own corticosteroid ho...n no test that could detect it in a blood sample. ...eek in Rapid Communications in Mass Spectrometry d...
Other Biology News:Supercomputing equipment to advance the frontiers of computational biology 2Fast test for low blood flow in dogs detects early heart trouble 2Fast test for low blood flow in dogs detects early heart trouble 3Fast test for low blood flow in dogs detects early heart trouble 4Two studies on bee evolution reveal surprises 2
RAT ANTI MOUSE METALLOPHILIC MACROPHAGES
All MagCellect Ferrofluid products perform optimally when used in conjunction with R&D Systems MagCellect Magnet. To accommodate different processing capacities, this neodymium iron boron permanent m
Request Info
Form: Concentrated Applications: ELISA
Biology Products: