Navigation Links
Start-Up ImmusanT Seeks to Restore Tolerance to Gluten in Celiac Disease with Immunotherapy
Date:3/15/2011

t for celiac disease, which have the potential to dramatically improve management of this lifelong disease," said Bob Anderson, PhD, MBChB, a gastroenterologist and highly respected international expert in immunology and clinical management of celiac disease at The Walter and Eliza Hall Institute of Medical Research.

Nexvax2 is delivered intradermally in small doses to reprogram and desensitize the disease-causing T-cells triggered by the patient's immune response to gluten. The approach is similar to treatments for allergies to cats, ragweed or dust mites, whereby repeated doses establish non-responsiveness to a specific antigen, and in the case of celiac disease, reduces or eliminates the body's rejection of dietary gluten. By reprogramming the T-cell response, the Nexvax2 approach is designed to reduce inflammation in the villi which line the small intestine and are responsible for absorbing nutrients. This returns the intestine to a normal healthy state.

Leveraging ImmusanT's proprietary peptide technology, the company has a commercial agreement with INOVA Diagnostics to develop improved serology diagnostic screening tests for celiac disease. In addition to using existing blood tests, currently the disease is diagnosed by a gastroenterologist using an endoscopic biopsy to take multiple tissue samples from the small intestine. In parallel, ImmusanT is developing a novel, simple whole-blood ELISA companion test to measure the activity of T-cells causing celiac disease and monitor optimal maintenance of immune tolerance with Nexvax2. Both diagnostic approaches may eliminate the need for an invasive surgical biopsy.

"With the formation of ImmusanT in Cambridge, we will have broad access to resources, capital and potential partners required to advance development of Nexvax2 and our companion diagnostics," said Leslie J. Williams, founder, president and chief executive officer of ImmusanT, Inc. "ImmusanT's near-term opportunity is to provi
'/>"/>

SOURCE ImmusanT, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Start-Up and Emerging Biotech Companies Will Tell Their Stories at Biosciences Showcase Planned for MichBio Expo
2. Enerkem announces first commercial-scale biofuels and biochemicals plant is entering start-up phase
3. BioLife Solutions Announces Validation and Start-Up of New Internal Manufacturing Facility for Serum-Free Cell and Tissue Biopreservation Media Products
4. San Diego Wireless Heavyweight Leap Wireless Supports New Start-up Incubator
5. Intel Corporation acquires Toronto start-up CognoVision
6. Osteotechs Next Generation Grafting Material, MagniFuse(TM) Bone Graft, a Breakthrough in Bone Regeneration; MagniFuse(TM) Bone Graft seeks to redefine the standard of care in the U.S. bone graft substitute market estimated to be in excess of $1.2 billio
7. Universal Bioenergy, Inc. Seeks Algae Feedstock Companies for Acquisition, Alliance, and Joint Venture Opportunities for Biodiesel Production
8. CTI Seeks Strategic Alternative for Italian Facility
9. MMR Seeks Its Slice of the Billion-Dollar Stimulus Pie
10. Syndication Inc. Seeks DIRECTOR OF TECHNICAL ENGINEERING for PINNACLE ENERGY - Its New Alternative Energy Subsidiary
11. Empirical Search Strategies Seeks Downside Protection Option at Avigen, Inc.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... YORK , Aug. 27, 2014 /PRNewswire/ ... research report is available in its catalogue: ... 2014-2018 http://www.reportlinker.com/p02316661/Global-Biodegradable-Packaging-Materials-Market-2014-2018.html ... materials are materials that are readily decomposed ... differs from conventional non-degradable packaging in terms ...
(Date:8/27/2014)... nature,s mysteries is how plants survive impact by ... sun,s rays, while using this energy for photosynthesis. ... the plant,s blades quickly dissipate the energy throughout ... Researchers at DTU Physics have now managed to ... and bacteria contain light-absorbing proteins which play a ...
(Date:8/27/2014)... , Aug. 27, 2014 Reportlinker.com announces ... in its catalogue: Global Chelating Agents ... About Chelating Agent A chelating agent ... bonds with metal ions, thereby forming a metal-ion ... metal-ions have on chemical processes, formulations, and the ...
(Date:8/27/2014)... , Aug. 27, 2014  Lisa Kulik saw ... this July 4 holiday, thanks to a groundbreaking retinal ... an internationally renowned clinician-researcher at the University of Southern ... 55-year-old Peoria, Ariz. resident who ... its victims of sight. On June 2, she became ...
Breaking Biology Technology:Global Biodegradable Packaging Materials Market 2014-2018 2Global Biodegradable Packaging Materials Market 2014-2018 3Global Biodegradable Packaging Materials Market 2014-2018 4Global Biodegradable Packaging Materials Market 2014-2018 5Global Biodegradable Packaging Materials Market 2014-2018 6Global Biodegradable Packaging Materials Market 2014-2018 7DTU researchers film protein quake for the first time 2Global Chelating Agents Market 2014-2018 2Global Chelating Agents Market 2014-2018 3Global Chelating Agents Market 2014-2018 4USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 2USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 3USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 4USC Eye Institute ophthalmologists implant first FDA-approved Argus II retinal prosthesis in western United States 5
... kind of fiber that could be tougher than Kevlar. ... from other universities and the MER Corporation, Horacio Espinosa, ... & Entrepreneurship at the McCormick School of Engineering and ... performance fiber from carbon nanotubes and a polymer that ...
... 2010 Baylor Research Institute (BRI), the research arm ... formed a three-year partnership with Roche (SIX: RO, ROG; ... human immunology platforms developed at the Baylor Institute for ... These programs will leverage BIIR,s leading position in human ...
... now Knight Commanders in the Order of the Netherlands Lion ... the 2010 Nobel Prize in Physics for their discovery of ... Nijmegen in the Netherlands. Professor Geim worked as an associate ... a Dutch citizen. Professor Novoselov received his PhD from ...
Cached Biology Technology:Researchers create new high-performance fiber 2Researchers create new high-performance fiber 3Roche, Baylor Research Institute Partner in Human Immunology Research 2Dutch royal honors for Manchester researchers 2
(Date:8/29/2014)... climatic shifts over the last 120,000 years may ... team of researchers led by City College of ... new biodiversity metric called "phylogeographic endemism." , It ... within species is restricted in geographical space. , ... 14 other researchers from institutions in Brazil, Australia ...
(Date:8/29/2014)... nucleus, chromosomal DNA is tightly bound to structural ... chromatin. Until about two decades ago, histones were ... material around which the glamorous DNA strands were ... appreciation for how DNA/histone interactions govern gene expression. ... studying the sequence of the genome from cancer ...
(Date:8/28/2014)... a handful of bacterial culprits that may drive inflammatory ... colitis, using patients, own intestinal immune responses as a ... the journal Cell . , Trillions of bacteria ... critical role in the development and progression of IBD. ... bacterial species affect a person,s susceptibility to IBD and ...
Breaking Biology News(10 mins):CCNY team defines new biodiversity metric 2'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 2'K-to-M' histone mutations: How repressing the repressors may drive tissue-specific cancers 3Yale study identifies possible bacterial drivers of IBD 2
... 18 July 2010 [Vienna, Austria]Encouraged by recent progress ... 20,000 participants from more than 185 countries have assembled ... AIDS Conference (AIDS 2010) today. Under the theme of ... the epidemic, noting the central role of human right ...
... thrive underground. Researchers writing in the open access journal ... identification of an adaptation in the blood of Eastern ... facilitating the moles, burrowing behavior. Kevin Campbell ... team of researchers to study the blood of three ...
... Kavli Prize Science Forum, WHEN: Monday, September 6, 3:00 ... OSLO, NORWAY, WHAT: Global leaders critical to shaping science ... Oslo for the first Kavli Prize Science Forum a ... major topics on science and science policy. The theme of ...
Cached Biology News:At opening of XVIII International AIDS Conference, scientific, community and political leaders applaud recent progress toward universal access and urge continued momentum to 'finish what we've started' 2At opening of XVIII International AIDS Conference, scientific, community and political leaders applaud recent progress toward universal access and urge continued momentum to 'finish what we've started' 3At opening of XVIII International AIDS Conference, scientific, community and political leaders applaud recent progress toward universal access and urge continued momentum to 'finish what we've started' 4At opening of XVIII International AIDS Conference, scientific, community and political leaders applaud recent progress toward universal access and urge continued momentum to 'finish what we've started' 5Adaptation in mole blood aids tunnelling 2
... platform, 220 V, is used for agitation and ... cultures, staining and destaining of gels and blots, ... control (8-40 rpm) and can handle a maximum ... features two 29 x 21 cm platforms covered ...
...
...
... of Wyatt Technology's family of light scattering ... high temperature chromatograph and enables you to ... polymers. The HTmD is easily installed in ... or Alliance 2000 device and enables you ...
Biology Products: