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Star Scientific Announces Successful Completion of Product Satisfaction Study - Results Show Potential for Development and Manufacturing of New Pharmaceutical Product for Smoking and Smokeless Tobacco Cessation
Date:1/6/2009

PETERSBURG, Va., Jan. 6 /PRNewswire-FirstCall/ -- Star Scientific (Nasdaq :STSI) announced today that its subsidiary, Rock Creek Pharmaceuticals, Inc., in conjunction with its Star Tobacco, Inc. subsidiary, recently completed a study to determine the ability of Stonewall(R) dissolvable smokeless tobacco to relieve cigarette withdrawal symptoms when compared to an over-the-counter nicotine replacement product (NRT). The study, which included 49 cigarette smokers, was designed to measure 1) nicotine's effects and 2) relief from smoking withdrawal symptoms, using a 4mg NRT product and a 4mg Stonewall piece, along with placebos of each product. The NRT, Stonewall product and the two placebos were administered over the course of four sessions. Both the nicotine replacement product and the 4mg Stonewall product were much more effective than their placebos in reducing nicotine craving, confirming the preliminary results published in 2007 in the journal Tobacco Control.

These results are important because they confirm the "proof of concept" hypothesis that is the basis of Rock Creek's focus on developing and manufacturing a low-cost, botanical-based NRT product to compete with NRT products now on the market. Rock Creek Pharmaceutical's strategies include the exploration, development and manufacturing of novel cessation and therapy products to change the current "status-quo" in smoking cessation and harm reduction strategies.

Dr. Curtis Wright, Chief Medical Officer of Rock Creek, commented, "Recent scientific and clinical studies, in addition to Rock Creek's completed product satisfaction study, strongly suggest the value of pursuing the development of a low-cost botanical-based NRT product for both smoking and smokeless tobacco cessation. We have to move beyond the current situation that makes NRT more expensive than continuing to use tobacco." Dr. Wright further commented that Rock Creek intends to apply to have the r
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SOURCE Star Scientific
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