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Stallergenes : Sublingual Desensitisation Tablets Oralair Grasses Approved in Germany
Date:6/24/2008

tural course of the disease. Nearly 15 to 20% of these patients suffer from moderate to severe allergic rhinitis and rhino-conjunctivitis, not controlled by their usual medical treatment.

Since 2003, Stallergenes has been carrying out the Oralair programme which addresses these unmet medical needs with EBM-documented, registered allergen tablets that are safe and easy-to-use.

This programme consists in the development of the four main allergens accounting for more than 80% of the epidemiology of these allergies: grass pollens, house dust mites, birch pollen and ragweed pollen.

The entire programme is in the clinical development stage and is proceeding according to schedule.

About Oralair(R) Grasses

With a safe and easy-to-use daily dose of Oralair(R) Grasses, patients enjoy a very significant alleviation of all their rhino-conjunctivitis symptoms, a marked reduction in their symptomatic medication use and a noticeable improvement in their quality of life.

Oralair(R) Grasses is a fast-dissolving tablet that has demonstrated high efficacy in allergic rhino-conjunctivitis to grass pollen in the first season, throughout the pollen season and at the pollen peak on:

- poly- and mono-sensitised patients, as well as asthmatic patients,

- every individual symptom, and in peculiar in nasal congestion and

watery eyes

Oralair(R) Grasses is a pre-coseasonal treatment: it has to be started four months before the pollen season, maintained throughout the season, then stopped and restarted the following season.

Oralair(R) Grasses contains a mix of 5 standardised grass allergens: perennial rye grass (Lolium perenne), meadow grass (Poa pratensis), timothy grass (Phleum pratense), cocksfoot (Dactylis glomerata) and sweet vernal grass (Anthoxanthum odoratum), as a daily dose of 300 IR, so as to mimic patients' natural exposure.

The clinical development programme has already enrolled around 1600 p
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SOURCE Stallergenes
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