Navigation Links
Spherix Announces Successful Completion of Important Toxicology Study of SPX-106
Date:1/11/2012

BETHESDA, Md., Jan. 11, 2012 /PRNewswire/ -- Spherix Incorporated (NASDAQ: SPEX) – an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis, and provider of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, today reported the successful completion of its 28-day rat toxicology study of its drug candidate, SPX-106.  Results demonstrated an ample margin of safety with the dosing planned for the first-in-human study.  The toxicology report will be included in the Investigational New Drug (IND) submission to the U.S. Food and Drug Administration (FDA), which is expected to be submitted in the second quarter of 2012.

The study also established that SPX-106 does not accumulate and is rapidly excreted after multiple days of dosing.  This study, in conjunction with earlier efficacy studies, continues to support SPX-106 as a component of a combination therapy for dyslipidemia.  Earlier tests have shown reduced dyslipidemia in apolipoprotein E‑deficient mice and Syrian Golden hamsters, as well as in LDL receptor-deficient mice.  SPX-106T, which is SPX-106 combined with D-tagatose, is thought to treat dyslipidemia by simultaneously blocking carbohydrate conversion to lipids and promoting lipid catabolism (lipid breakdown).  This latest study paves the way for the SPX-106T human clinical trial in 2012.

"I am pleased to report the successful achievement of a critical milestone, our first toxicology study of SPX-106.  These results advance our current development plan and support our belief that there are significant opportunities for our Company in the development of SPX-106T for the dyslipidemia market," reported Dr. Claire Kruger, CEO of Spherix.

About Spherix

Spherix Incorporated was launched in 1967 as a scientific research company under the name Biospherics Research.  The Co
'/>"/>

SOURCE Spherix Incorporated
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Spherix Announces Third Quarter Financial Results
2. Spherix Announces Closing of Private Placement of $1.25 Million, Discusses Use of Proceeds
3. Spherix to Raise $1.25 Million in Private Placement
4. Spherix Announces Results from New Preclinical Studies Showing SPX-106T Produces Significant Reductions in Cholesterol, Fat Deposition and Body Weight
5. Spherix Announces Annual Shareholders Meeting Date
6. Spherix to Present at the 5th Lippert/Heilshorn Life Sciences & Medical Technologies Virtual Conference on June 16
7. Spherix Regains Compliance With NASDAQ Listing Rule
8. Spherix Announces First Quarter Financial Results
9. Spherix Announces Reverse Stock Split Effective May 6, 2011
10. Spherix to Effect Reverse Stock Split
11. Spherix Announces 2010 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... 22, 2014 Nuclear reactors are used ... by controlled fission chain reaction in nuclear reactors is ... used to drive a power- generating turbine. Currently nuclear ... world’s total electricity production. Nuclear reactor market is expected ... planned and proposed nuclear reactor projects. , Early buyers ...
(Date:7/22/2014)... Automated cell culture systems are instruments that mechanically ... allow production of optimum cells at a large scale ... and industries and biopharmaceutical companies. Cell culture automation systems ... cell-based assays, and cellular expression systems as they save ... Global Cell Culture market will grow at ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 The ... clear and concise visual representation of history, migration, and ... was always regaled by family history stories stemming from ... as the "old country." Pictures and 8mm home movies ... side of the family, and Steve ordered a test ...
(Date:7/22/2014)... 2014 OHAUS Corporation, a leading ... balances and scales, proudly announces its Explorer line ... Equipment magazine’s 2014 “Readers' Choice” Award for ... the Explorer was voted the best laboratory balance ... Awards celebrates “excellence in product design and performance ...
Breaking Biology Technology:Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 2Nuclear Energy Market: Global Industry Analysis, Size, Share, Analysis, Growth and Forecast 2013 - 2019 3Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 2Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 3Global Cell Culture Market to Grow at 10.27% CAGR by 2018 Forecasts a New Research Report ReportsnReports.com 4DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 2DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 3DNA Test from DNA Spectrum Shows Heritage Like a Map of the Past 4OHAUS Explorer Voted “Best Balance” in Laboratory Equipment’s 2014 Readers’ Choice Awards 2
... Building the Merge Healthcare of tomorrow, as ... offshoring 150 jobs to a "more cost effective workforce" ... of the financially troubled medical imaging software company's workforce ... the competitive edge marks the centerpiece of a broader ...
... - TeraMedica , a medical informatics company, has ... the VisLite Information Manager , an ... , ,The product integrates and manages advanced and traditional ... records and health records. , ,It also uses open ...
... spend the most on research and development in the life ... University of Wisconsin-Madison ($764 million) is perennially among the ... the list is the Medical College of Wisconsin ... research centers. Next up is the University of Wisconsin-Milwaukee ...
Cached Biology Technology:Merge offshoring jobs to "more cost-effective" workforce 2Merge offshoring jobs to "more cost-effective" workforce 3Marshfield Clinic and UW combine to speed tech growth 2Marshfield Clinic and UW combine to speed tech growth 3Marshfield Clinic and UW combine to speed tech growth 4
(Date:7/23/2014)... grip is affecting more than the color of people,s lawns. ... heat-loving amoeba commonly found in warm freshwater bodies, such as ... warmer than usual this year. , A 9-year-old Kansas girl ... swimming in several area lakes. The amoeba enters the body ... brain. Nose plugs can lower the odds of this rare ...
(Date:7/23/2014)... commonly found in dead bodies and is used in ... to as the post mortem interval. A report of ... Tamil Nadu is provided for the first time based ... DNA barcoding. This study, significant in forensic investigations was ... . , Chrysomya megacephala is commonly found ...
(Date:7/23/2014)... around the world by 2050, according to one of ... Change (IPCC), may be advantageous to the physiology and ... of forage plants such as Stylosanthes capitata Vogel ... countries such as Brazil., The conclusion is from a ... Biology at the Ribeiro Preto Faculty of Philosophy, Sciences ...
Breaking Biology News(10 mins):Diseases of another kind 2Dead body feeding larvae useful in forensic investigations 2An increase in temperature by 2050 may be advantageous to the growth of forage plants 2An increase in temperature by 2050 may be advantageous to the growth of forage plants 3An increase in temperature by 2050 may be advantageous to the growth of forage plants 4
... Davis researchers in nanotechnology, chemistry and biology now have access ... in the world. The new Spectral Imaging Facility, opened this ... a laser scanning confocal microscope, the first commercial machine of ... Asylum Research of Santa Barbara and the confocal microscope system ...
... gained new insights into how neurons control growth ... that enable them to connect with their neighbors. ... which neurons form the signaling networks that constitute ... neuronal growth will help researchers better understand brain ...
... preliminary results from a study in Botswana, Harvard School ... HIV-1 subtype C in resource-poor settings, who receive antiretroviral ... the developed world. A fully supported health care delivery ... data published in November 2005 issue of the Journal ...
Cached Biology News:How the neuron sprouts its branches 2How the neuron sprouts its branches 3Largest computational biology simulation mimics life’s most essential nanomachine 2
Mouse monoclonal antibody raised against a partial recombinant KRT4. NCBI Entrez Gene ID = KRT4...
Mouse monoclonal antibody raised against a partial recombinant ALPK3. NCBI Entrez Gene ID = ALPK3...
... Lines ,High Quality, Functionally-Validated, Ion Channel Cell ... for having a critical role in nerve ... key function in pain, CNS and the ... been investigated in therapeutic areas, such as ...
... ,High Quality, Functionally-Validated, Ion Channel Cell Lines ... having a critical role in nerve and ... function in pain, CNS and the heart. ... investigated in therapeutic areas, such as neuropathic ...
Biology Products: