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Spectral announces publication demonstrating Toraymyxin(TM) significantly reduces mortality from sepsis in prospective controlled trial
Date:6/18/2009

Mean Arterial Pressure (MAP) increased (76 to 84 mm Hg; P = 0.001) in the Toraymyxin(TM) group but not in the conventional therapy group (MAP, 74 to 77 mm Hg; P = 0.37). - Vasopressor requirement decreased (inotropic score, 29.9 to 6.8; P (less than) 0.001) at 72 hours in the Toraymyxin(TM) group but not in the conventional therapy group (inotropic score, 28.6 to 22.4; P = 0.14). - Sequential Organ Failure Assessment scores improved in the Toraymyxin (TM) group but not in the conventional therapy group (change in SOFA, -3.4 vs -0.1; P (less than) 0.001). The abstract and full text of the article is available online at www.jama.ama-assn.org and appears in JAMA. 2009; Vol. 301 # 23, 2445-2452. About Spectral Diagnostics

Spectral is a leader in the battle against sepsis. Spectral's lead product is its Endotoxin Activity Assay (EAA(TM)), the only FDA cleared assay for the measurement of endotoxin. With the growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies being developed for this indication, Spectral is well-positioned to drive the adoption of the EAA(TM), which can be used to identify patients, enable therapeutics and monitor treatment. In March 2009, Spectral obtained the exclusive development and commercial rights in the U.S. for Toraymyxin(TM), a therapeutic for the treatment of sepsis that removes endotoxin from the bloodstream. Spectral will seek FDA approval for Toraymyxin(TM) and intends to commercialize the product together with EAA(TM). Spectral is listed on TSX under the symbol SDI.

Forward-looking statement

Information in this news release that is not current or historical factual information may constitute forward-looking information within the meaning of securities laws. Implicit in this information, particularly in respect of the future outlook of Spectral
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SOURCE Spectral Diagnostics Inc.
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Related biology technology :

1. Spectral announces first quarter 2009 results
2. Spectral announces presentations at the 29TH International Symposium on Intensive Care and Emergency Medicine focusing on the role of endotoxin
3. Spectral announces 2008 financial results
4. Spectral signs exclusive license agreement to bring sepsis therapeutic to the U.S. market
5. Surface plasmon resonances of metal nanoparticles in array can have narrower spectral widths
6. Spectral announces third quarter 2008 results
7. Spectral to bring anti-sepsis therapy to the U.S. market
8. Spectral announces exclusive distribution agreement in Russia for its EAA(TM) Sepsis Diagnostic Assay
9. Spectral announces continuing support for the combination of EAA(TM) and anti-endotoxin therapeutics
10. Spectral announces presentation of data on improving sepsis patient management with EAA(TM) and Toraymyxin(TM) combination
11. Spectral and Toray expand collaboration to include new geographic territories
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