Navigation Links
Spectral announces publication demonstrating Toraymyxin(TM) significantly reduces mortality from sepsis in prospective controlled trial
Date:6/18/2009

TORONTO, June 18 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI), a company developing products for the treatment of sepsis, today announced that findings demonstrating the Toraymyxin(TM) cartridge, a blood purification device that absorbs endotoxin from the bloodstream, when added to conventional therapy, significantly improved hemodynamics and organ dysfunction and reduced 28-day mortality in patients with severe sepsis and septic shock. The article entitled "Early Use of Polymyxin B Hemoperfusion in Abdominal Septic Shock: The EUPHAS Randomized Controlled Trial," was published in the Journal of the American Medical Association (JAMA). Spectral has exclusive rights to Toraymyxin(TM) in the United States and plans to initiate a trial in the U.S. in the latter half of 2009.

"The degree of reduction in mortality demonstrated by Toraymyxin(TM) in the EUPHAS trial is an unprecedented result for sepsis therapies and indicates that this product has the potential to fulfill an unmet need for the approximately 100,000 patients that develop severe sepsis or septic shock in the U.S. each year," said Dr. Paul Walker, President and CEO of Spectral Diagnostics. "Our Endotoxin Activity Assay (EAA(TM)) has the ability to identify patients who could benefit from this therapy and monitor its effect. Together, this diagnostic and therapeutic have the potential to provide a more effective treatment for patients with severe sepsis and septic shock caused by endotoxemia."

The objective of this study was to determine whether Toraymyxin(TM), when added to conventional medical therapy, improves clinical outcomes and mortality compared with conventional therapy alone, in a targeted patient population with severe sepsis and/or septic shock associated with intra-abdominal infections.

    -   28 day mortality was 32% (11/34 patients) in the Toraymyxin(TM) group
        and 53% (16/30 patients) in the conventional therapy group.
    - 
'/>"/>
SOURCE Spectral Diagnostics Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Spectral announces first quarter 2009 results
2. Spectral announces presentations at the 29TH International Symposium on Intensive Care and Emergency Medicine focusing on the role of endotoxin
3. Spectral announces 2008 financial results
4. Spectral signs exclusive license agreement to bring sepsis therapeutic to the U.S. market
5. Surface plasmon resonances of metal nanoparticles in array can have narrower spectral widths
6. Spectral announces third quarter 2008 results
7. Spectral to bring anti-sepsis therapy to the U.S. market
8. Spectral announces exclusive distribution agreement in Russia for its EAA(TM) Sepsis Diagnostic Assay
9. Spectral announces continuing support for the combination of EAA(TM) and anti-endotoxin therapeutics
10. Spectral announces presentation of data on improving sepsis patient management with EAA(TM) and Toraymyxin(TM) combination
11. Spectral and Toray expand collaboration to include new geographic territories
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... , , Collaboration to Create Optimized Antibodies ... Cancer , MISSISSAUGA, ON, Dec. 10 /PRNewswire-FirstCall/ - YM ... results of a collaborative program between YM and the ... Institute (NRC-BRI). Utilizing YM,s IntelliMab(TM) technology, the program is ...
... challenges miniaturizing transistors, the key active components in nearly ... or switch electronic signals. Now, ... and Applied Science, Purdue University and IBM have successfully ... transistors. These nanowires which ...
... - Sirius Genomics, a developer of pharmacogenomic diagnostics, announced today ... Officer, replacing Dr. Brad Popovich. , "We want to thank ... the last four years. Brad has taken the Company from ... of time. Brad has also managed to recruit one of ...
Cached Biology Technology:YM BIOSCIENCES AND THE NATIONAL RESEARCH COUNCIL OF CANADA BIOTECHNOLOGY RESEARCH INSTITUTE (NRC-BRI) PRODUCE NEW BREAST CANCER DRUG CANDIDATES 2YM BIOSCIENCES AND THE NATIONAL RESEARCH COUNCIL OF CANADA BIOTECHNOLOGY RESEARCH INSTITUTE (NRC-BRI) PRODUCE NEW BREAST CANCER DRUG CANDIDATES 3YM BIOSCIENCES AND THE NATIONAL RESEARCH COUNCIL OF CANADA BIOTECHNOLOGY RESEARCH INSTITUTE (NRC-BRI) PRODUCE NEW BREAST CANCER DRUG CANDIDATES 4YM BIOSCIENCES AND THE NATIONAL RESEARCH COUNCIL OF CANADA BIOTECHNOLOGY RESEARCH INSTITUTE (NRC-BRI) PRODUCE NEW BREAST CANCER DRUG CANDIDATES 5New silicon-germanium nanowires could lead to smaller, more powerful electronic devices 2New silicon-germanium nanowires could lead to smaller, more powerful electronic devices 3Sirius Genomics Announces Change in Leadership 2
(Date:11/18/2014)... 2014   News Highlights: ... develop The Partners Data Lake, an agile data ... Lake will allow researcher and clinicians to explore ... the lives of patients , The Partners ... across the Partners system, breaking down physical barriers ...
(Date:11/15/2014)... YORK , Nov. 13, 2014  While we may ... technology Doctor McCoy used in "Star Trek" to gain instant ... tools designed to work with smartphones and tablets for monitoring ... of the healthcare world. This may seem a tad Orwellian ... ready to adopt some of these technological opportunities into their ...
(Date:11/10/2014)... appearing on U.S. store shelves in early 2010, and ... The small packets can be tossed into a washing ... or powder. The convenience, though, has come with risks ... at Nationwide Children,s Hospital found that from 2012 through ... children younger than 6 years of age swallowing, inhaling, ...
Breaking Biology News(10 mins):Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 2Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 3Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 4Partners HealthCare and EMC Unite to Solve Health Care's Toughest Challenges Using Big Data 5Americans May Be Ready for a Brave New World of Healthcare 2Americans May Be Ready for a Brave New World of Healthcare 3Americans May Be Ready for a Brave New World of Healthcare 4Study finds laundry detergent pods, serious poisoning risk for children 2
... - In the July issue of Biomaterials , ... Florida (UCF) report on the first lab-grown motor nerves ... in the human body. The model system will ... such as diabetic neuropathy and later, possibly multiple sclerosis ...
... (BOSTON) July 21, 2009 - A menace to ... the World Organisation for Animal Health (OIE) has declared ... cattle-killing disease that threatened its food supply and its ... July 25, 2009. A team from Tufts University,s ...
... , This release is available in German ... enriching samples, then separating, identifying, and counting the bacteria. This ... arrival of the sample in the laboratory. Tests that work ... being precise and error-free, are thus high on the wish ...
Cached Biology News:Researchers design first model motor nerve system that's insulated and organized like the human body 2Ethiopian government celebrates rinderpest eradication 2Ethiopian government celebrates rinderpest eradication 3Reveal the enemy 2
... magnetic particle based purification systems provide high ... any sample. They offer increased throughput and ... systems- KingFisher, KingFisher mL and KingFisher 96, ... l. Each system consists of an instrument, ...
... The DNA120OP is specifically engineered for ... sturdy design incorporates a glass cover and ... fully automated, unattended, odor-free processing of samples ... System for Synthetic Oligos ...
... The SPD101B is a no-frills, basic ... institution. Although economically priced, this unit still ... with a digitial display of time and ... aqueous samples and accepts a wide variety ...
... The first SpeedVac to have active, ... Explorer SpeedVac System is the worlds first, ... components can be stacked together to form ... valuable benchspace. It is also the first ...
Biology Products: