Navigation Links
Specific populations of gut bacteria linked to fatty liver
Date:1/31/2011

tly the same diets, everyone's gut microbe mixture would begin to look similar, with the microbial communities converging. It did not happen everybody was clearly individual throughout the entire study," Spencer noted.

"So we also looked at how the patients' microbes actually changed in pattern, even though they remained distinct from each other," she said. "The patterns of change were very interesting. Some of the patterns were very distinct in themselves."

The researchers noticed that among the numerous classes of bacteria present in each patient, variations in the populations of two particular groups seemed to correspond with variations between patients in the degree to which they developed a fatty liver during the period of dietary choline depletion.

"Those patients with the highest abundance of Gammaproteobacteria at the beginning of the study seemed to have the lowest fatty liver development. The ones with the least developed the most fatty liver," Spencer noted. "Erysipeoltrichi showed exactly the opposite association, though this relationship was not quite as strong. So there seemed to be change going on in opposite directions."

When the trends of Gammaproteobacteria abundance and Erysiptoltrichi scarcity were combined and related to fatty liver development, the relationship became even stronger.

Finally, the researchers factored in individual genetic variations that affect internal production of the nutrient choline and that should explain why some patients developed fatty liver and others did not. Surprisingly, the results showed that each person's genetics did not entirely account for their fatty liver outcome. When the researchers modified the analysis to include the abundances of the two bacterial groups and each individual's genetics, the correlation between fatty liver development and these three factors was nearly perfect. Further mathematical tests were performed to show that the correlations were n
'/>"/>

Contact: James Hathaway
jbhathaw@uncc.edu
704-687-5743
University of North Carolina at Charlotte
Source:Eurekalert

Page: 1 2 3 4

Related biology technology :

1. BioSpecifics Announces Positive Results From Clinical Trial in Canine Lipomas
2. BioSpecifics Technologies Corp. to Present at UBS Global Life Sciences Conference
3. BioSpecifics Technologies Corp. to Present at Rodman & Renshaw 12th Annual Healthcare Conference
4. Breast-Specific Gamma Imaging In Clinical Practice as an Adjunct Imaging Modality for Diagnosis of Breast Cancer
5. Reissue with Tables: BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results
6. Calbiotech Awarded U.S. Army Phase I SBIR Research Contract to Develop Analyte Specific Reagents for the Diagnosis of Dengue Fever Virus
7. BioSpecifics Technologies Corp. Reports Third Quarter 2009 Financial Results
8. BioSpecifics Technologies Corp. to Host Conference Call to Report Third Quarter 2009 Financial Results on November 5, 2009
9. ImaginAb, Inc. and BZL Biologics, LLC Conclude Licensing Agreement for Imaging Rights to huJ591/Prostate-Specific Membrane Antigen (PSMA)
10. Bionovo to Present on Novel Female-Specific Drugs for Obesity at the 20th Annual Meeting of the North American Menopause Society
11. Accredited Construct Specific PCR Test for Recently Detected Unapproved GM Flax/Linseed FP967/CDC Triffid Available Through Genetic ID
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... September 16, 2014 CIRTEC Medical Systems’ ... Highley as CEO of CIRTEC. , “I am ... for the Company.” noted Brian Highley. “The company has ... sustaining strong organic growth over the past two years. ... continuing to improve and expand the services Cirtec offers ...
(Date:9/16/2014)... 16, 2014   Synthetic Biologics, Inc. ... anti-infective biologic and drug programs targeting specific pathogens ... completion of the Company,s Investor Day in ... irritable bowel syndrome (IBS) program, including its novel, ... In the keynote presentation, Mark Pimentel ...
(Date:9/16/2014)... Arizona (PRWEB) September 16, 2014 ... develops safe and effective products to treat patients ... use of a proprietary SPACE™ Technology Platform announced ... and President will present at the White Hat ... at the Hyatt Regency Phoenix. In addition, ...
(Date:9/16/2014)... BARBARA, Calif. , Sept. 16, 2014 /PRNewswire-iReach/ ... Strength index (BMSi) test identifies patients with bone ... cannot.  Over 160 million people worldwide are at ... detected by today,s standard bone strength test, the ... the 2014 American Society for Bone and Mineral ...
Breaking Biology Technology:Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 2Synthetic Biologics' Statin-Class Candidate for Constipation-Predominant Irritable Bowel Syndrome Detailed at Company's Investor Day 3Convoy Therapeutics to Present at WhiteHat Investor Conference September 18, 2014 2Convoy Therapeutics to Present at WhiteHat Investor Conference September 18, 2014 3ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 2ActiveLife's BMSi Test Provides Hope for 160 Million with Undetectable Risk of Bone Fracture 3
... Jan. 4 Anadys Pharmaceuticals,Inc. (Nasdaq: ANDS ) ... Annual,JPMorgan Healthcare Conference on Thursday, January 10, 2008 at ... held at the Westin St. Francis,Hotel in San Francisco., ... of Anadys,Pharmaceuticals, Inc., will present an update and overview ...
... 4 ARCA Discovery Inc., a privately held,biopharmaceutical ... other cardiovascular diseases, today announced Richard B.,Brewer, President ... 26th,Annual JPMorgan Healthcare Conference on Tuesday, January 8 ... Conference will be held January 7-10, 2008 at,the ...
... NEW YORK, Jan. 4 QED International ... a series of,20 underlying fund portfolios, today ... on Monday January 7, 2008, Alexion Pharmaceutical, ... Pharmaceutical, Inc. (Nasdaq: ASPV ) in,the ...
Cached Biology Technology:Anadys Pharmaceuticals to Present at the JPMorgan Healthcare Conference 2ARCA Discovery, Inc. to Present at 26th Annual JPMorgan Healthcare Conference on January 8, 2008 2QED International Associates Announces Changes to the HealthShares(TM) Autoimmune-Inflammation and Neuroscience Indexes - Correction 2
(Date:9/16/2014)... tree species has its own bacterial identity. That,s the ... other institutions who studied the genetic fingerprints of bacteria ... island. , "This study demonstrates for the first time ... different ecological strategies possess very different microbial communities on ... former postdoctoral researcher in the UO,s Institute of Ecology ...
(Date:9/16/2014)... A complex web of interaction between viruses, bacteria, ... by a growing international collaboration between Matthew Sullivan, ... of Ecology and Evolutionary Biology and Steven Hallam ... Canada. , "Bacteria are drivers of nutrient ... said. "As the climate is changing, so are ...
(Date:9/16/2014)... extravagant, colorful tail feathers in courtship of a peahen. ... camera developed by an engineer at Washington University in ... choose their mates based on a similar display. , ... used a bioinspired polarization camera developed by Viktor Gruev, ... Washington University, to make the discovery. His camera has ...
Breaking Biology News(10 mins):Microbiome research shows each tree species has a unique bacterial identity 2New research decodes virus-host interactions in ocean dead zones 2New research decodes virus-host interactions in ocean dead zones 3Camera developed at WUSTL sheds light on mate choice of swordtail fish 2
... Nov. 9, 2007 Researchers at Childrens Hospital of ... currently underway to study the effectiveness of oral insulin in ... people at risk for the disease. The researchers want ... or delay the onset of type 1 diabetes in relatives ...
... Flip through the 133 page record of the 2006-2007 activities ... and youll see why they recently took home the nations ... toss fundraiser. Youll find the detailed lesson plans that ... to 75 fifth grades at Spreckels elementary school last year. ...
... helping an effort to eradicate malaria, the mosquito-borne disease ... Researchers at the National Institute of Standards and Technology ... a young company create weakened, harmless versions of the ... to create a new type of vaccine that shows ...
Cached Biology News:Children's Hospital studying drug with the potential to prevent/delay onset of type 1 diabetes 2UC-San Diego Engineering Honor Society wins most outstanding chapter award 2Bug-Zapper: A dose of radiation may help knock out malaria 2
... The Label IT siRNA Tracker Intracellular ... to directly label and deliver siRNA, of ... manner, for in vitro tracking experiments. Subcellular ... expression can be monitored following introduction of ...
... This CLS number is a ... easily match Cornings product number. ... please order under the old ... customer service for assistance. ID ...
... through the extracellular matrix (ECM) is an ... cells initiate invasion by adhering to and ... Proteolytic enzymes, such as MMP collagenases, dissolve ... membrane) surrounding the blood vessels to allow ...
... Cell Invasion Assay is designed to determine ... as a significant barrier to invasion or ... in a convenient, high-throughput, 96-well format. The ... all types of adherent cells such as ...
Biology Products: