Navigation Links
Sosei Group Corporation QVA149 Phase III Study Meets Primary Endpoint in Reducing Exacerbations in COPD Patients and Filings in EU and Japan by End of Year
Date:8/29/2012

ternational clinical trial programs in COPD comprising 10 studies in total with more than 7,000 patients across 42 countries[1-5,13-20]. The first five studies (ILLUMINATE, SHINE, BRIGHT, ENLIGHTEN, SPARK) have already completed in 2012 with three additional studies (BLAZE, ARISE, BEACON) expected to complete by the end of the year. The studies are designed to investigate efficacy, safety and tolerability, exercise endurance, exacerbations, breathlessness and quality of life[1-5,13-17].

CEO of Sosei, Shinichi Tamura commented:

"The SPARK study demonstrated a meaningful reduction in exacerbations in COPD patients; something that is of major benefit for patients and doctors and eases the burden of healthcare costs. We look forward to more detailed data from both glycopyrronium bromide (NVA237) and QVA149 at the upcoming European Respiratory Society meeting in Vienna in early September with the first filings for QVA149 expected in Europe and Japan by the end of this year."

Notes for editors

About NVA237/QVA149

NVA237 (glycopyrronium bromide - Seebri® Breezhaler®) was licensed to Novartis in April 2005 by Sosei and its co-development partner, Vectura. It is an investigational LAMA developed as a once-daily inhaled maintenance therapy for the treatment of COPD. Phase III data from the GLOW1, 2 and 3 studies demonstrated that glycopyrronium bromide increased patients' lung function over a 24-hour period compared to placebo with a fast onset of action at first dose, and improved exercise endurance versus placebo[21-23].

QVA149 is an investigational inhaled, once-daily, fixed-dose combination of NVA237 and the LABA, indacaterol maleate, for which Novartis received European regulatory approval as Onbrez® B
'/>"/>

SOURCE Sosei Group Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. Sosei Announces Successful Completion of Phase I Study for SO-1105 for the Treatment of Oropharyngeal Candidiasis
2. AtheroNova and Maxwell Biotech Group Ratify Agreement to Develop New Atherosclerosis Drug
3. MiMedx Group, Inc. to Present at the 6th Annual Canaccord Genuity Cardiovascular, Aesthetics and Metabolic Disorders Conference
4. BioNeutral Group Receives $400,000 in Equity Financing
5. MiMedx Group Completes $5,000,000 Private Placement
6. Use Biomarkers in Alzheimers Disease Clinical Trials, Says Expert Group
7. MiMedx Group, Inc. Receives CE Certification for Its CollaFix™ Surgical Mesh CD
8. Lend Lease Announces the Appointment of Tom Chapman as Director Operations for the Life Sciences Group in the Atlantic Region
9. Statewide Network of Angel Investor Groups Announced in Alabama
10. Simcere Pharmaceutical Group to Announce Fourth Quarter and Fiscal Year 2011 Financial Results on Wednesday, March 7, 2012
11. Weikang Bio-Technology Group Co., Inc. Is Expected to Achieve the Net Profit of at Least $26 Million
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... Sterlitech is proud to announce that ... stable of products . These additional products ... include membrane filters with surface charges. , ... for our membrane process testing equipment, and correspondingly, a ... membranes,” explains Sterlitech President Mark Spatz. “The addition ...
(Date:8/28/2014)... work by a Florida State University research team has ... your temperature, emit white light, and convert photon energy ... like a butterfly. , Biwu Ma, associate professor in ... FAMU-FSU College of Engineering, created the molecule in a ... discover that his creation has many other unique capabilities. ...
(Date:8/28/2014)... 28, 2014 A new market ... world is available from Strategic Consulting, Inc., the ... Industrial Microbiology Market Review, Fourth Edition: Global Review ... (IMMR—4) tracks and compares microbiology test volumes, market ... Europe and Asia, and forecasts future volumes and ...
(Date:8/28/2014)... PrimeSource Building Products, Inc., a leading ... to support their communication needs with the ... conferencing platform GlobalMeet powered by SoundConnect. The solution ... SoundConnect delivers award winning “results driven” business class ... be utilizing GlobalMeet powered by SoundConnect ...
Breaking Biology Technology:Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3PrimeSource Chooses SoundConnect as Collaboration Provider 2
... , , , , For purification of up to 10 mg ultrapure plasmid , ... use gravity-flow anion-exchange tips for efficient , purification of plasmid DNA , ... Features and benefits , , ... equivalent to that obtained by 2x CsCl-gradient centrifugation , ...
... , , , , For ultrafast purification of up to 750 ... Features and benefits , , ... ultrapure DNA , ... No risk of DNA pellet loss during precipitation , ...
... , , , , , , ... QIAGEN GmbH, Hilden, Germany , ... modification , of neuronal cells by delivery of either siRNA ... and Kosik reported silencing , of endogenous genes in primary ...
Cached Biology Technology:HiSpeed Plasmid Kits 2Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 2Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 3Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 4Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 5Efficient DNA transfection of primary CNS neurons using TransMessenger , Transfection Reagent 6
(Date:8/31/2014)... Climate Change , suggests that if current trends continue ... global targets for total greenhouse gas (GHG) emissions in 2050. ... carefully about the food we choose and its environmental impact. ... one of a number of actions that need to be ... enough food for all. , As populations rise and ...
(Date:8/29/2014)... Until recently, little has been known about what genetic ... team of scientists, one of whom is a University ... showing that genes controlling the development of the brain ... domestication., The study was published Aug. 28 in ... It is online at http://www.sciencemag.org/ ., The domestication ...
(Date:8/29/2014)... news release is available in German . ... chemical signals between organisms is considered the oldest form ... interactions between conspecifics, for example, the sexual attraction between ... social responses and to coordinate reproductive behavior in males ... the University of the Algarve in Faro, Portugal, and ...
Breaking Biology News(10 mins):Changing global diets is vital to reducing climate change 2Changing global diets is vital to reducing climate change 3Changing global diets is vital to reducing climate change 4New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3Ready for mating at the right time 2Ready for mating at the right time 3
... This press release is available in ... packaging mealworms infected with beneficial nematodes could improve the ... biological control agents. The machine is the result ... Department of Agriculture (USDA) scientists and Southeastern Insectaries, Inc., ...
... CitiusTech announced today that its BI-Clinical platform ... ACO quality measures that are part of the ACO ... BI-Clinical can now help ACO participants assess ... four domains - patient / caregiver experience, care coordination ...
... trial was random, regulated, double-blinded and broad-based. The drug was ... with Type 1 diabetes a short time before joining the ... in Europe, Israel and South Africa. The patients in the ... received the trial drug (DiaPep277) through a subcutaneous injection once ...
Cached Biology News:Special delivery: Nematode-infected insect cadavers 2BI-Clinical Offers 100% Coverage of All ACO Quality Measures Released by CMS 2Andromeda Biotech: A drug for type 1 diabetes 2
Collected from 8-12 week old sexually mature rats. Pricing: $100/unit for 1 - 10 units...
PlusOne Acrylamide PAGE, 1 kg. Category: Electrophoresis Systems & Standards & Reagents, Electrophoresis Standards and Reagents, Gel Casting Chemicals....
... Kit is one of the most ... of RNA in solution. The ... than absorbance measurements. As little as ... fluorescence microplate readers and fluorometers using ...
... The GenoStat Inducible Expression System provides tightly ... mammalian cells and is capable of repeated ... is mediated by the highly specific interaction ... bipartite nuclear receptor complex. Gene expression levels ...
Biology Products: