Navigation Links
Sosei Group Corporation QVA149 Phase III Study Meets Primary Endpoint in Reducing Exacerbations in COPD Patients and Filings in EU and Japan by End of Year
Date:8/29/2012

pared to open-label (OL) tiotropium 18 mcg[1].

A further analysis of the data demonstrated that QVA149 was statistically significantly more effective in reducing the overall rate of all exacerbations (mild, moderate and severe) compared to glycopyrronium 50 mcg (p=0.001) and OL tiotropium 18 mcg (p=0.002)[1]. The adverse event (AE) profile of QVA149 was similar to both glycopyrronium 50 mcg and OL tiotropium 18 mcg[1].

The management of COPD exacerbations is important to both patients and physicians, as exacerbations can impose a significant burden of morbidity, mortality, reduced quality of life and healthcare costs[6,7]. Frequent exacerbations are linked to an accelerated decline in lung function[8,9] and patients are also known to have a poorer quality of life[10]. Admissions to hospital due to exacerbations are increasing[11] and patients with more severe underlying disease account for around 70% of the direct medical costs of COPD[12].

SPARK was a 64-week, multi-center, randomized, double-blind, parallel-group, active controlled study designed to evaluate the effect of QVA149 (indacaterol maleate 110 mcg / glycopyrronium 50 mcg) QD versus glycopyrronium 50 mcg and QD OL tiotropium 18 mcg on moderate-to-severe COPD exacerbations in 2,224 patients with severe to very severe COPD[1].

QVA149 is an investigational inhaled, once-daily, fixed-dose combination of the long-acting beta2-adrenergicagonist (LABA) indacaterol maleate, and the investigational long-acting muscarinic antagonist (LAMA) glycopyrronium bromide, being investigated for the treatment of COPD in the Phase III IGNITE clinical trial program. IGNITE is one of the largest in
'/>"/>

SOURCE Sosei Group Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related biology technology :

1. Sosei Announces Successful Completion of Phase I Study for SO-1105 for the Treatment of Oropharyngeal Candidiasis
2. AtheroNova and Maxwell Biotech Group Ratify Agreement to Develop New Atherosclerosis Drug
3. MiMedx Group, Inc. to Present at the 6th Annual Canaccord Genuity Cardiovascular, Aesthetics and Metabolic Disorders Conference
4. BioNeutral Group Receives $400,000 in Equity Financing
5. MiMedx Group Completes $5,000,000 Private Placement
6. Use Biomarkers in Alzheimers Disease Clinical Trials, Says Expert Group
7. MiMedx Group, Inc. Receives CE Certification for Its CollaFix™ Surgical Mesh CD
8. Lend Lease Announces the Appointment of Tom Chapman as Director Operations for the Life Sciences Group in the Atlantic Region
9. Statewide Network of Angel Investor Groups Announced in Alabama
10. Simcere Pharmaceutical Group to Announce Fourth Quarter and Fiscal Year 2011 Financial Results on Wednesday, March 7, 2012
11. Weikang Bio-Technology Group Co., Inc. Is Expected to Achieve the Net Profit of at Least $26 Million
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/8nqqdw/global_breast ) has announced ... Monoclonal Antibodies Market Outlook 2020" report to ... dominate the breast cancer monoclonal antibody segment because ... has been able to dominate this segment for ... cells become recalcitrant and relapsed condition could not ...
(Date:5/27/2015)... May 27, 2015  Tikcro Technologies Ltd. (OTCQB: TIKRF) ... 31, 2015. Aviv Boim , ... pre-clinical work to generate functional specific antibodies, targeting identified ... we are encouraged by the development progress. We are ... antibodies which modulate immune checkpoints gain clinical acceptance for ...
(Date:5/27/2015)... Md. , May 27, 2015  Northwest Biotherapeutics, ... company developing DCVax® personalized immune therapies for cancer, announced ... Technical Officer of the Company, will be making an ... Meeting in Chicago on Saturday, ... at the Industry Expert Theater in McCormick Place. ...
(Date:5/27/2015)... May 27, 2015  RXi Pharmaceuticals Corporation (NASDAQ: ... discovering and developing innovative therapies primarily in the ... on the status of the Company,s Series A ... Logo - http://photos.prnewswire.com/prnh/20130917/NE80755LOGO ... 21 shares of Series A Preferred Stock and ...
Breaking Biology Technology:Global Breast Cancer Monoclonal Antibodies Market Outlook 2020 2Global Breast Cancer Monoclonal Antibodies Market Outlook 2020 3Tikcro Technologies Reports First Quarter 2015 Results 2Tikcro Technologies Reports First Quarter 2015 Results 3NW Bio To Present Overview Of DCVax-Direct Phase I Trial In Chicago This Weekend 2NW Bio To Present Overview Of DCVax-Direct Phase I Trial In Chicago This Weekend 3RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 2RXi Pharmaceuticals Provides an Update on Series A and Series A-1 Preferred Stock 3
... of financial technology solutions and subsidiary of Marshall and ... Virginia and Pennsylvania. , ,On Monday the company announced they ... origination solutions headquartered in Wayne, Pa. GHR was acquired for ... the third quarter of 2005. , ,Metavante said in their ...
... 18,000 people who recently attended BIO 2005 in Philadelphia made me ... its also becoming mainstream in the world economy. , ,It also ... 1960s. Though most adults at first wouldnt accept it, the launch ... a statement that rock was here to stay. So is biotech! ...
... be misleading to suggest that scientists at UW-Madison or anywhere ... fact, no scientist in the state has even announced plans ... to suggest the process for cloning a human embryo for ... from the process used in therapeutic cloning. The first step ...
Cached Biology Technology:Biotech phenomenon becoming mainstream in world economy 2Biotech phenomenon becoming mainstream in world economy 3Biotech phenomenon becoming mainstream in world economy 4Biotech phenomenon becoming mainstream in world economy 5The Attack of the Clones: No, its not a summer movie 2The Attack of the Clones: No, its not a summer movie 3
(Date:5/22/2015)...  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or the ... its promotional pricing and making the Wocket generally available for ... , Head of Marketing said, "We,ve extended the opportunity to ... of May. To get your wocket at this special price, ... store on June 1, you,ll receive a unique code that ...
(Date:5/20/2015)... -- NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... LLC, a company engaged in biometric identification is an ... portion of the recently awarded TIES (Technical Information Engineering ... Army. 3D-ID LLC has a suite of ... and security agencies. Gino Pereira , ...
(Date:5/14/2015)... --Research and Markets ( http://www.researchandmarkets.com/research/5whpxg/fingerprint ) has ... in Smart Mobile Devices " report to their ... a watershed year for fingerprint sensors in smartphones and ... gave fingerprint sensors a raison d,etre in the mobile ... a must-have feature in flagship smartphones. The ...
Breaking Biology News(10 mins):NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 3NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3Global Smart Mobile Devices Fingerprint Sensors Market 2015-2019: Key Vendors are Authentec, Validity Sensors, Fingerprint Cards, Next Biometrics Group. IDEX, and Qualcomm 2
... by a University of Tennessee, Knoxville professor has found ... human colonization. Research by Alison Boyer, a ... an international team studied the extinction rates of nonperching ... 3,500 years ago. Some of the birds studied included ...
... is best known for promoting erections, it may also serve as ... healthy "brown fat" relative to unhealthy "white fat" than it would ... online in The FASEB Journal , this is ... well known as a messenger molecule used by the body to ...
... School of Medicine have discovered a new biological pathway ... identified agents that can block it, leading to increased ... pneumonia. They reported their findings today in Nature ... an inflammatory response from the body that is more ...
Cached Biology News:University of Tennessee professor links massive prehistoric bird extinction to human colonization 2Drug for erectile disorder show promise in the treatment of obesity 2Pitt team finds immunity protein that ramps up inflammation, and agents that can block it 2
... The Staccato Application Series are ... systems designed to provide fast and ... Utilizing proven and robust "automation-friendly" building ... solutions that cost less than conventional ...
... Guava has made microcapillary flow cytometry accessible ... experts alike will appreciate the latest addition ... Pluseasy to use, surprising affordable, and very ... system includes such features as absolute cell ...
... Rotator, variable speed, timer, SB3, Fully adjustable ... of tube holders to hold a number ... SB3 is ideal for aerating cultures, keeping ... mixing applications., The rotator can be used ...
... Accuri's C6 Flow Cytometer System is a full ... system including: the C6 Flow Cytometer, CFlow Software, ... C6 Flow Cytometer System provides all the capabilities ... fraction of the price. The C6 Flow Cytometer ...
Biology Products: