Navigation Links
Sopherion Therapeutics, LLC Announces Publication of Phase I/II Myocet(R) (Nonpegylated Liposomal Doxorubicin) Data in Advanced Breast Cancer Patients
Date:2/5/2009

PRINCETON, N.J., Feb. 5 /PRNewswire/ -- Sopherion Therapeutics, LLC, a biopharmaceutical company focused on the development and commercialization of anti-cancer therapies, today announced the publication of data from a phase I/II study of nonpegylated liposomal doxorubicin (Myocet(R)) in the January 1 issue of Clinical Cancer Research. The study was supported by a grant from Roche and was conducted by the Spanish Breast Cancer Cooperative Group (SOLTI).

The study results suggest that Myocet(R), in combination with the approved trastuzumab (Herceptin(R)) plus paclitaxel (Taxol) treatment regimen, yielded an unusually high clinical response rate in patients with HER-2 overexpressing breast cancer. The 3-drug combination was well tolerated. There were no cases of treatment-related symptomatic congestive heart failure. This is noteworthy because cardiotoxicity is a common and therapy-limiting adverse event of the anthracycline class of anti-cancer agents and because Herceptin(R) has its own, well recognized, potential for cardiac toxicity.

Myocet is a liposomal delivery system for doxorubicin designed to reduce the risk of cardiotoxicity associated with doxorubicin while preserving its antitumor efficacy. It is currently in Phase III development in the United States for the treatment of advanced breast cancer.

"These clinical results are encouraging because they suggest that use of a nonpegylated liposomal anthracycline, such as Myocet, may provide important therapeutic benefits, while diminishing cardiac toxicity," said Ronald H. Goldfarb, Ph.D., President and CEO of Sopherion Therapeutics. "Moreover, the incidence of hand foot syndrome, a rate limiting toxicity of other liposomal anthracyclines, is rare with nonpegylated liposomal anthracyclines. We look forward to reporting additional data from ongoing Myocet clinical trials, which further test this concept in patients with advanced breast cancer."<
'/>"/>

SOURCE Sopherion Therapeutics, LLC
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Cell Therapeutics, Inc. (CTI) to Present at 11th Annual BIO CEO & Investor Conference
2. Cell Therapeutics, Inc. Provides Update on the Special Meeting of Shareholders
3. Cell Therapeutics, Inc. Announces Single Institutional Investor Purchases $32.65 Million of Senior Convertible Notes
4. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
5. Cell Therapeutics, Inc. (CTI) Zevalin Joint Venture Conference Call to be Webcast with Slides
6. Cell Therapeutics, Inc. (CTI) to Discuss Zevalin Joint Venture with Spectrum Pharmaceuticals
7. Cell Therapeutics, Inc. (CTI) to Report 2008 Third Quarter Financial Results on November 7
8. Laureate Pharma Announces Agreement with Tolera Therapeutics, Inc.
9. Tobira Therapeutics, Inc. to Present at the 2008 BIO Investor Forum
10. Cell Therapeutics, Inc. Announces Single Institutional Investor Purchases $24.7 Million of Senior Convertible Notes
11. Cell Therapeutics, Inc. (CTI) to Present at Three Upcoming Investor Conferences
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2015)... BEIJING , July 24, 2015 Origin Agritech ... supplier of crop seeds in China , ... third quarter fiscal year 2015 ended June 30, 2015, before ... The Company will host a teleconference on August 5th, 2015, ... time to discuss the results. To participate in ...
(Date:7/24/2015)... -- , Adds integrated small molecule drug ... for chronic kidney disease and oncology patients , ... dermatology , Increases group revenue and earnings ... a leading China -based biotechnology company ... today announced that it has acquired the entire equity ...
(Date:7/23/2015)... ANGELES , July 23, 2015 ImmunoCellular Therapeutics, ... to report financial results for the second quarter 2015 on ... a conference call and webcast on that day at 5:00 ... and provide a business update. The call will be hosted ...   , , , LIVE CALL: ...
(Date:7/23/2015)... (PRWEB) , ... July 23, 2015 , ... Science and ... radiation, to new drug therapies and devices – according to Susan Chang, MD, director ... a session on how science and new technology are impacting the development of new ...
Breaking Biology Technology:Origin Agritech Limited to Announce Third Quarter Fiscal 2015 Unaudited Financial Results on August 5th, 2015 2Origin Agritech Limited to Announce Third Quarter Fiscal 2015 Unaudited Financial Results on August 5th, 2015 33SBio Acquires Zhejiang Wansheng Pharmaceutical 23SBio Acquires Zhejiang Wansheng Pharmaceutical 33SBio Acquires Zhejiang Wansheng Pharmaceutical 4ImmunoCellular Therapeutics to Report Second Quarter 2015 Financial Results on August 6, 2015 2Experts Present How Science and New Technology are Driving New Brain Tumor Treatments and Improving Quality of Life 2Experts Present How Science and New Technology are Driving New Brain Tumor Treatments and Improving Quality of Life 3
... 14 GenVault Corporation today,announces that Mr. Mark ... of Business Development. Mr. Sutherland will be responsible ... licensing the company,s products and technologies as well ... Sutherland has more than 25 years experience in ...
... Oct. 14 Imaging,Diagnostic Systems, Inc., (OTC Bulletin ... imaging systems, announced today that its,distributor, Laszlo Meszaros ... Laser Mammography (CTLM(R)) system for Budapest, Hungary., ... system will be installed at the new MeDoc ...
... enable patient care services in Australia through ... retail pharmacies ... Convention --,Mirixa Corporation, the leader in pharmacy-based patient care services ... that they have signed a definitive technology licensing and business,consulting ...
Cached Biology Technology:Mark Sutherland Joins GenVault as Senior Vice President, Business Development 2Imaging Diagnostic Systems Sells Its CT Laser Mammography System to Budapest, Hungary 2Mirixa Announces Agreement With the Pharmacy Guild of Australia 2Mirixa Announces Agreement With the Pharmacy Guild of Australia 3
(Date:6/29/2015)... 2015 Research and Markets( ... "Latin America Biomedical Sensors Market - Growth, Trends & ... The Latin America Biomedical Sensors market is estimated at ... over the period 2014-2020 The near future ... genetic formulation of each individual. These sensors can be ...
(Date:6/25/2015)... According to a new ... Area), Technology, Material (Optical Prism, Piezoelectric, Capacitive & ... Others) & Geography - Global Forecast to 2014 ... is expected to reach $14,500.07 Million by 2020, ... Browse 76 market Tables and 109 Figures spread ...
(Date:6/25/2015)... N.J. , June 25, 2015  TAKE Solutions ... a patent by the United States Patent and Trademark ... Standardization". This process leverages TAKE Solutions, Clinical Accelerators to ... over 50% (when compared to standardization without the accelerators), ... At the heart of ...
Breaking Biology News(10 mins):Latin America Biomedical Sensors Market Report 2015-2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 2Fingerprint Sensors Market Worth $14,500.07 Million by 2020 3Fingerprint Sensors Market Worth $14,500.07 Million by 2020 4TAKE Solutions Awarded Patent By USPTO 2
... the Inderscience publication, the International Journal of Environment ... from various fields explain how living organisms can ... pollutants, particulates, and trace elements. Borut Smodi, ... provides an editorial explaining how biomonitoring can be ...
... on the theory that dinosaurs, closest living relatives are ... a 68-million-year-old Tyrannosaurus rex protein from the dinosaur,s femur ... chickens, ostriches, and to a lesser extent, alligators. ... rex femur discovered in 2003 by paleontologist John Horner ...
... Mont. -- Natural barriers like waterfalls play an important ... National Park, so maintaining those barriers should be a ... four-year study in the park. Park workers might ... the water from rising behind those barriers, said graduate ...
Cached Biology News:Biomonitoring 2Genetic sequencing of protein from T. rex bone confirms dinosaurs' link to birds 2Montana State researchers study spread of lake trout in Glacier National Park 2
...
... Clone/PAD: 3B8A10. ... to the C-terminal region ... Specificity: Specific for the ... Reactivity: Human (positive control: ...
Negative Control, eluted and packaged aseptically in 20l of 10mM Tris-HCL, pH 8.0, 1 mM EDTA, 5 years at either 4°C or -20°C...
...
Biology Products: