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SomaGenics' sshRNA Technology Demonstrates Efficacy of RNAi Against Hepatitis C Virus

  • The therapeutic effect was convincingly demonstrated to act through an RNAi mechanism.

  • About Hepatitis C Virus

    HCV is a leading cause of cirrhosis, liver cancer, and liver failure requiring liver transplant. An estimated 170 million people are infected with HCV globally, with 3-4 million new infections each year. No vaccine for HCV is currently available.

    About RNAi and SomaGenics' sshRNA Technology

    The Nobel-prize-winning discovery of RNA interference (RNAi), a process by which double-stranded RNA molecules can inhibit the function of virtually any gene, has spurred interest in the development of short interfering RNAs as drugs. SomaGenics has pioneered the discovery and development of a unique class of short interfering RNAs called sshRNAs. Structurally distinct from the more commonly used siRNAs and expressed shRNAs, sshRNAs are short, chemically modified RNA sequences that are chemically synthesized as single strands. They have outstanding potency and possess attractive pharmacokinetic properties without undesirable immune stimulation.  

    About SomaGenics

    SomaGenics is a privately held company that develops innovative RNA technologies for therapeutic and diagnostic uses. SomaGenics' lead therapeutic program, against hepatitis C virus, has successfully completed efficacy evaluations in preclinical animal models and is ready for clinical development.


    Dr. Sumedha Jayasena
    VP, Therapeutic Development
    2161 Delaware Avenue
    Santa Cruz, CA 95060

    This press release was issued through eReleases(R).  For more information, visit eReleases Press Release Distribution at

    SOURCE SomaGenics, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

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