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Smith & Nephew Announces Agreement To Acquire Assets Of Healthpoint Biotherapeutics
Date:11/28/2012

the next decade and beyond."

Commenting, Olivier Bohuon, Chief Executive Officer of Smith & Nephew, said: "The acquisition of Healthpoint is an important step for Smith & Nephew, and for our Advanced Wound Management division. Strategically, it gives us a strong position in the fastest growing area of advanced wound management – bioactives. And it does this bringing material revenues from a fast growing product range, an attractive pipeline, and the commercial and R&D capabilities upon which we can build. The combination creates a truly unique wound care business – having leadership positions across exudate and infection management, negative pressure and bioactives to offer to our customers."

Deutsche Bank is serving as financial adviser to Smith & Nephew on the transaction and Bank of America Merrill Lynch and JP Morgan served as financial advisers to Healthpoint.

About HP802-247

HP802-247 is an investigational allogeneic living human cell suspension that consists of two components that are sprayed sequentially on the wound bed at the time of treatment: a fibrinogen solution and a cell preparation containing a mixture of growth arrested, living, allogeneic epidermal keratinocytes and dermal fibroblasts.

Based on in vitro studies, HP802-247 is believed to release various growth factors and cytokines into the micro-environment of the wound. These living cells are anticipated to interact with the patient's own cells to stimulate wound healing. HP802-247 has been designed to deliver a defined cell ratio (keratinocyte:fibroblasts) to allow safe and optimal tissue regeneration.

Positive topline results for a Phase IIb clinical trial investigating the efficacy of HP802-247 in venous leg ulcers were recently announced. The study was a randomized, double blind, dose-finding study involving 228 subjects enrolled across 35 investigational centers in the United States. Overall, HP802-247 achieved
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SOURCE Healthpoint Biotherapeutics
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