Navigation Links
Sirnaomics and GRL Establish Partnership for the Development of Two Multi-Targeted RNAi Therapeutics Products
Date:3/12/2008

ROCKVILLE, Md., March 12 /PRNewswire/ -- General Research Laboratory, Inc. (GRL) and Sirnaomics, Inc. announced today that the companies are advancing their partnership initiated in July 2007 for development of two RNA interference (RNAi) therapeutic products, following the successful identification of siRNA inhibitors for multi-targeted siRNA cocktail approaches, through a series of in silico and in vitro studies, using Sirnaomics' Tri-Blocker(TM) technology.

Under the terms of the agreement, Sirnaomics and GRL will jointly focus on developing two multi-targeted RNAi therapeutic products to improve scarless skin wound healing and to treat prostate cancer. The first product is expected to consist of three siRNA duplexes targeting three genes involved in scar formation during the skin wound healing process. The further in vivo study will demonstrate that the siRNA/polymeric nanoparticle formulation with topical cream application is able to enhance the wound healing process with minimum scar formation. The second product is defined as an siRNA cocktail targeting three tumor causing genes delivered with Epoxy Encapsulated Magnetic Nanoparticles (EEMNP) system. Using this local and in vivo administration approach will greatly enhance the therapeutic benefit for treatment of prostate carcinoma.

Under the terms of the agreement, GRL will provide Sirnaomics with research funding and access to lab and office space. Sirnaomics will receive milestone payments at key points in the development process and product royalty payments when these products reach the market. "We are very pleased to have this partnership with GRL which not only provides us with financial resources but also validates our product development strategy," said Dr. Patrick Lu, Founder, President and CEO of Sirnaomics, Inc. "We will continue seeking additional partnerships for our multi-targeted siRNA therapeutic approach, either from large pharmaceutical and major biotech companies, or fr
'/>"/>

SOURCE Sirnaomics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Sirnaomics Received Multiple Government Fundings For Its Multi-Targeted siRNA Therapeutics Programs
2. Debiopharm and EPFL Establish an Oncology Chair
3. Ardea Biosciences Establishes Scientific Advisory Board for Inflammation Program
4. International Confocal Microscopy Working Group Established to Advance Practice of Reflective Confocal Microscopy
5. Rosetta Genomics Establishes Medical Advisory Board
6. Ardea Biosciences Establishes Scientific Advisory Board for HIV Program
7. Inverness - Chemogen Establish Exclusive License for TB Antibodies
8. Sureshield Coatings Company Established to Market Industry-Leading Portfolio of Advanced Coatings for Metal Surfaces
9. Sigma-Aldrich and the Universite de Montreal Establish Collaboration for RNA Interference Studies
10. Cellumen Establishes Collaboration in Breast Cancer Patient Stratification
11. KGI and Smith College Establish Leadership Forum for Women in Bioscience
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/3/2015)... MARIETTA, Ga. , Aug. 3, 2015  MiMedx ... medicine company utilizing human amniotic tissue and patent-protected processes ... the Wound Care, Surgical, Orthopedic, Spine, Sports Medicine, Ophthalmic ... will present at the 35 th Annual Canaccord|Genuity ...  Parker H. "Pete" Petit, Chairman and CEO, William ...
(Date:8/3/2015)... Delaware , August 3, 2015 ... in the commercialization of its Bio-electrical Signal Therapy device ... noninvasive treatment of hard to heal chronic wounds, today ... agreement with Chemipal, an Israeli distributor specializing in medical ... device. Chemipal is a 70 years old, ...
(Date:7/31/2015)... VEGAS , July 31, 2015 ... seek resources that help them drive positive health ... a vital source of patient care in their ... annual tradeshow and conference, AmerisourceBergen announced a ... its Pharmacy Services Administration Organization and help independent ...
(Date:7/30/2015)... 2015 AACC welcomed thousands of medical ... Annual Meeting & Clinical Lab Expo in ... meeting showcased revolutionary advancements in clinical testing technology ... providers to diagnose patients quickly and accurately and ... As of Wednesday, July 29, more ...
Breaking Biology Technology:MiMedx To Present At 35th Annual Canaccord|Genuity Growth Conference 2E-QURE Corp Signs Second Distribution Agreement in Israel 2E-QURE Corp Signs Second Distribution Agreement in Israel 3AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 2AmerisourceBergen Unveils Suite of Enhanced Capabilities for Independent Pharmacies at ThoughtSpot 2015 3Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 2Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 3Innovative Research on Cancer, Heart Disease, and Infectious Diseases Draws More than 17,500 Attendees to 2015 AACC Annual Meeting 4
... , , , High-quality ... efficient gene silencing in eukaryotic cell culture by targeting complementary , ... , gene silencing in functional genomics studies. Now, ... service that includes a range of modifications , ...
... , , Stefanie Schrer, Werner Wittke,* and , ... Germany , , * Leica ... , Laser microdissection (LMD) provides a powerful , ... This eliminates the problems of cell-type heterogeneity within tissue samples , ...
... , , The proven activated dendrimer for transfection , ... Features and benefits , , ... range of cell lines , Transfection in the presence of serum ... ") , High transient and stable transfection efficiencies , ...
Cached Biology Technology:Custom and library siRNA for efficient gene silencing 2Custom and library siRNA for efficient gene silencing 3Custom and library siRNA for efficient gene silencing 4Custom and library siRNA for efficient gene silencing 5Laser microdissection and nucleic acid purification - a Leica - QIAGEN , cooperation 2Laser microdissection and nucleic acid purification - a Leica - QIAGEN , cooperation 3Laser microdissection and nucleic acid purification - a Leica - QIAGEN , cooperation 4SuperFect Transfection Reagent 2SuperFect Transfection Reagent 3
(Date:7/9/2015)... , July 9, 2015  Synaptics Inc. (NASDAQ: SYNA ... today that it will report financial results for the ... 30, 2015 after the close of market. The company ... investors at 2:00 p.m. PT (5:00 p.m. ET), during ... To participate on the live call, analysts and investors ...
(Date:7/8/2015)... , July 8, 2015 Summary ... and the fourth most fatal, with a mortality rate ... poor prognosis of pancreatic cancer patients has highlighted a ... which is not being met by the current market. ... array of products with varying molecule types and mechanisms ...
(Date:7/7/2015)... Research and Markets ... the "Capacitive Fingerprint Sensors Patent Landscape" ... date, fingerprint sensing technology is the most reliable ... well developed. This patent landscape focuses on fingerprint ... domain of capacitive fingerprint sensors is closely linked ...
Breaking Biology News(10 mins):Synaptics to Report Fourth Quarter, Fiscal Year 2015 Results on July 30 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 2Frontier Pharma: Pancreatic Cancer - Identifying and Commercializing First-in-Class Innovation 3Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2
... are consuming at least double the recommended amount of salt ... at the University of Gothenburg and Sahlgrenska University Hospital. "It,s ... and something needs to be done about it. We can ... salt intake later on in life, in the form of ...
... discovered a chemical compound in a sponge off Palau, ... shown anticancer, antibacterial, and antifungal pharmaceutical promise. But that ... This compound, called Palau,amine, is so chemically complex ... laboratory became the most hotly pursued synthetic chemistry goal ...
... birds can help pinpoint likely carrier species and geographic ... to enter North America, according to new U.S. Geological ... pathogenic avian influenza H5N1 (HPAI H5N1) virus in Eurasia ... transported among continents by migratory birds has resulted in ...
Cached Biology News:Scripps Research team wins global race to achieve landmark synthesis of perplexing natural product 2Scripps Research team wins global race to achieve landmark synthesis of perplexing natural product 3Scripps Research team wins global race to achieve landmark synthesis of perplexing natural product 4New research findings can improve avian flu surveillance programs 2