Navigation Links
Simple blood test can detect lung cancer with high sensitivity and specificity - results from large clinical validation study published in the Journal of Clinical Oncology
Date:1/13/2014

LONDON, MILAN, and SAN DIEGO, Jan. 13, 2014 /PRNewswire/ -- GENSIGNIA Ltd, a London-based, privately held molecular diagnostics company with laboratory operations in San Diego, CA, and Fondazione IRCCS, Istituto Nazionale dei Tumori (INT), Milan, a National Cancer Research Center in Italy, announced today that positive clinical validation results for the microRNA signature classifier (MSC) Lung Cancer assay were published in the Journal of Clinical Oncology (JCO). The results demonstrate for the first time that a blood-based test can significantly reduce the high false positive rate associated high resolution imaging, specifically with Low-Dose Computed Tomography (LDCT or Spiral CT), the current recommended lung cancer screening methodology for heavy smokers.  The MSC Lung Cancer assay had high sensitivity and detected lung cancer up to 2 years prior to diagnosis by LDCT. Aspects of the study results were presented on January 8th in San Diego as a plenary talk at the AACR-IASLC Molecular Origins of Lung Cancer meeting by Gabriella Sozzi, Ph.D., Professor, Head of Cancer Genomics at INT. In 2014, GENSIGNIA intends to introduce a lung cancer diagnostic test initially in the U.S.

(Logo:  http://photos.prnewswire.com/prnh/20140113/LA41250LOGO)

Prospectively collected blood samples from 939 heavy smokers from the randomized lung cancer screening trial comparing LDCT versus observation (Multicentric Italian Lung Detection [MILD] trial; INT) were used to validate the diagnostic performance and demonstrate clinical utility of the MSC Lung Cancer assay, a 24 microRNA expression signature assay. Heavy smokers from the MILD trial t
'/>"/>

SOURCE GENSIGNIA Ltd
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Winter Construction is Simple with Starrco’s Modular Office Systems
2. VolitionRx Finds Simple Blood Test Detects 85% of Colorectal Cancers and Over 50% of Polyps
3. KLOX Technologies annonce quelle a obtenu lapprobation européenne du marquage CE sur son produit novateur et non invasif pour lacné simple
4. CONRAD presents new technology combining contraception, HIV and herpes simplex virus-2 prevention
5. NanoBio To Present Data At ICAAC Supporting The Development Of Safe And Effective RSV & Herpes Simplex Virus-2 Vaccines
6. DNA2.0 Introduces Simple, IP-Free©, Scarless Cloning
7. A Simple Guide to De-Risking Before Full Prescribing Information, New Life Science Webinar Hosted by Xtalks
8. SimpleSeq Webless by Eurofins MWG Operon for Order-Free DNA Sequencing
9. IMDx Obtains CE-Marking for an Automated Molecular Test for Detection and Differentiation of Herpes Simplex Viruses 1 and 2
10. Simple, cheap way to mass-produce graphene nanosheets
11. Quest Diagnostics CE Marks Simplexa™ Test for Cytomegalovirus for Sale in Europe
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2014)... 21, 2014 During his lifetime Richard ... need to surround himself with great people and take ... his friends often marveled at his extraordinarily courageous attitude ... life and -- even with his death impending—that’s how ... disease that would ultimately take his life. , Carrying ...
(Date:11/22/2014)... Frederick, MD (PRWEB) November 21, 2014 ... sample management solutions provider, has released Limfinity® version ... more installation projects of Limfinity® than ever in ... majority configuration and minority framework enhancement. Limfinity® version ... goes far above and beyond bug fixes! , ...
(Date:11/22/2014)... Grand Rapids, MI (PRWEB) November 22, 2014 ... the opportunity to simulate the proper management of ... training and test lung devices . Grand Rapids-based, ... Lung” plans to donate two of the respiratory ... $12,000 to $15,000 each. Grand Valley and Muskegon ...
(Date:11/21/2014)... LAVAL, Quebec , November 21, 2014 ... KLOX como responsable comercial   Mariano Rodríguez ... finanzas   KLOX está en marcha para ... tratamiento de cura de heridas de reciente aprobación en Europa ... o "la compañía") se complace al anunciar los siguientes nombramientos: ...
Breaking Biology Technology:Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 2Sherry Sharp, Wife of CarMax Founder, Richard Sharp, Accepts Seat on Board of Cure Alzheimer’s Fund 3RURO Announces Limfinity® version 5.1.4 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 2Michigan Instruments Donates Two Respiratory Simulation Training and Test Lung (TTL) Devices to Grand Valley State University 3KLOX Technologies anuncia sus nombramientos ejecutivos 2KLOX Technologies anuncia sus nombramientos ejecutivos 3KLOX Technologies anuncia sus nombramientos ejecutivos 4KLOX Technologies anuncia sus nombramientos ejecutivos 5
... This release is available in German . ... as healthy food supplements. However, the production of this ... strains are robust enough to survive conventional production processes. ... particularly gentle method that allows the use of thus ...
... oldest known life-forms, but they are not well understood. ... microorganisms were designated as a domain of life distinct ... Robert Gunsalus, a UCLA professor of microbiology, immunology ... because of their ability to thrive in harsh ...
... ,   Skyline Diagnostics ... marketing of gene signature-based,diagnostic assays based in The ... Agreement with Johnson & Johnson,Pharmaceutical Research and Development ... Skyline,using its proprietary knowledge and technologies in the ...
Cached Biology Technology:TUM researchers develop environmentally friendly process to improve storage stability of probiotics 2TUM researchers develop environmentally friendly process to improve storage stability of probiotics 3Old life capable of revealing new tricks after all 2Old life capable of revealing new tricks after all 3Skyline Diagnostics Establishes Research Collaboration With Janssen 2
(Date:11/4/2014)... November 4, 2014   ... growth   Fuel3D , a developer of ... funding round totaling $6.4 million (£4 million). This funding builds ... earlier this year and paves the way for the commercial ... The funding round was led by Chimera Partners and ...
(Date:11/3/2014)... Cancer Center study published in this month,s ... describes the activity of a recently discovered communication molecule ... It has been known to limit inflammation and the ... system: IL-37 inhibits the ability of the immune system ... mechanism that underlies IL-37,s effect on the immune system ...
(Date:11/2/2014)... LA (2 November 2014)—In support of a bold quest ... & Melinda Gates Foundation today announced an award of ... Vaccine Initiative (MVI) in building new vaccines that will ... realize the "accelerating to zero" agenda. Such vaccines would ... could be called an "immunological bed net." , ...
Breaking Biology News(10 mins):Fuel3D Secures $6.4 Million in Expansion Funding 2Fuel3D Secures $6.4 Million in Expansion Funding 3PNAS: From HIV to cancer, IL-37 regulates immune system 2New malaria vaccines to prevent infection and block transmission get a shot in the arm 2New malaria vaccines to prevent infection and block transmission get a shot in the arm 3New malaria vaccines to prevent infection and block transmission get a shot in the arm 4
... of speech in humans. Crucial for the process are acoustic ... to a disturbed vocal development both in humans and in ... they either develop no or a rudimentary form of human ... are removed from their parents and are raised apart from ...
... can be embarrassing, but a new study suggests that ... Turku, Finland, interviewed more than three thousand men - ... younger brothers - about the first time they had ... had suffered from erectile dysfunction and premature ejaculation at ...
... Metrology Laboratory in the United Kingdom and the University of ... how the proportions of isotopes in a chemical element (atoms ... numbers of neutrons) vary throughout the length of a single ... these methods to track the geographical movements of people, including ...
Cached Biology News:A bad performance is better than no performance at all 2Sulphur in just one hair could blow a terrorist's alibi 2Sulphur in just one hair could blow a terrorist's alibi 3
IMAGEQUANT 100 WKSTN, 1 EA. Category: ImageQuant CCD Imagers....
The FlowTACS Apoptosis Detection Kit is designed specifically for in situdetection of apoptotic...
RayBio Human Cytokine Antibody Array 1.1 (4 array membranes) with Accessory, detects 20 cytokines (for lysate) Class: Antibody Array Products Product Group: Antibody Array...
HybriWell™ hybridization sealing system, 22 mm x 22 mm chamber, 0.15 mm deep *set of 100*...
Biology Products: