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Signalife Presence at XIII World Congress on Cardiac Pacing and Electrophysiology
Date:12/3/2007

STUDIO CITY, Calif., Dec. 3 /PRNewswire-FirstCall/ -- Signalife, Inc. (Amex: SGN) has announced its presence at the XIII World Congress on Cardiac Pacing and Electrophysiology to be held December 2-6, 2007 in Rome, Italy. At the Congress, Dr. Muricio Arruda, who has been testing Signalife's wireless Fidelity 400 Intracardiac Monitor at the Electrophysiology Laboratories of the Cleveland Clinic Heart Center, will present a prototoype of the Fidelity 400 Intracardiac Monitor to selected participants. The Signalife Fidelity 400 Intracardiac Monitor applies Signalife's award-winning proprietary physiological signal acquisition and amplification technology to read intracardiac signals procured from intracardiac catheter products. An intracardiac catheter is a flexible tube that is inserted through a vein in the leg and fed into the heart. The catheter is equipped with electrodes which allows the signal to be recorded within the heart, and the catheter data is transmitted to a monitor, which allows the physician to evaluate cardiac function, including arrhythmia, or irregular heartbeat. These readings are beneficial in that they measure signals directly from the heart, as opposed to signals read from the surface of the body as is typical in the ordinary application of heart monitors.

The mission of the World Congress of Cardiac Pacing and Electrophysiology is to provide an education forum, underlining evidence-based clinical practices in the field of arrhythmology for clinical cardiologists and electrophysiologists. The Congress will also highlight the latest and most advanced topics in invasive electrophysiology and cardiac pacing, giving leading electrophysiologists the opportunity to demonstrate and discuss new diagnostic and therapeutic strategies.

Dr. Arruda, a faculty member of the XIII World Congress, stated: "I am very happy and impressed with the progress made by the Signalife research & development team on the Fidelity 400 multi- channel, wireless ECG/IC system from the initial results presented at the 2006 Heart and Rhythm Society Conference. The main objective and benefit of the novel system is to offer a technology that overcomes problems presently associated with recordings of surface ECG and intracardiac signals during electrophysiological studies".

Dr. Budimir Drakulic, Signalife's Chief Technology Officer, stated: "We have applied Signalife's patented signal processing technology to intracardiac signals with the same success realized with ambulatory ECG recordings and are looking forward to further development of this technology. We intend to file this one-of-a-kind intra-cardiac monitor for FDA approval shortly."

Dr Lowell Harmison, Signalife's President, states that "this technology application will allow us to get new data concerning a host of electrophysiological changes in the heart that were not impossible to be obtained before. Our electrocardiography technology is opening new opportunities for medical research and clinical findings based on getting a more accurate and definitive ECG signal in the catheterization lab and surgery as well as under conditions of stress and a spectrum of ambulatory conditions. It is becoming a powerful new tool for cardiac monitoring and for improved cardiac care."

About Signalife

Signalife, Inc. is a life sciences company focused on the monitoring and detection of disease through continuous biomedical signal monitoring. Signalife uses its patented signal technology to design and develop medical devices that simplify and reduce the costs of diagnostic testing and patient monitoring in an ambulatory setting.

Signalife is publicly traded on the American Stock Exchange under the symbol SGN. The website for the company is http://www.Signalife.com. Clear Data. Trusted Results.

Caution Regarding Forward-Looking Statements

Statements in this release that are not strictly historical are "forward- looking" statements. Forward-looking statements involve known and unknown risks, which may cause Signalife's actual results in the future to differ materially from expected results. Factors which could cause or contribute to such differences include, but are not limited to, failure to complete the development and introduction of heart monitoring and other biomedical devices incorporating Signalife's technology, failure to obtain federal or state regulatory approvals governing heart monitoring and other biomedical devices incorporating Signalife's technology, inability to obtain physician, patient or insurance acceptance of for heart monitoring and other biomedical incorporating Signalife's technology, and the unavailability of financing to complete management's plans and objectives, including the development of heart monitoring and other biomedical incorporating Signalife's technology. These risks are qualified in their entirety by cautionary language and risk factors set forth and to be further described in Signalife's filings with the Securities and Exchange Commission.


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SOURCE Signalife, Inc.
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