Navigation Links
Signal Genetics Announces Publication of BreastPRS™ Validation Study with Weill Cornell Medical College, New York
Date:7/23/2013

New York, NY (PRWEB) July 23, 2013

Signal Genetics today announced that the results of a retrospective Weill Cornell validation study of BreastPRS, a novel series of prognostic and molecular profiling algorithms for breast cancer, has been published in the medical journal ‘Breast Cancer Research and Treatment’. Signal Genetics, LLC, is a privately held molecular diagnostic company based in New York, NY and Little Rock, AR.

Ryan Van Laar, Ph.D., Head of Bioinformatics & New Product Development at Signal Genetics said “We are excited about the results of this independent study, which determines that our BreastPRS test has the potential to provide physicians improved breast cancer prognostication and more critical personalized information. It is now much more than a viable alternative.”

The publication is titled “BreastPRS is a gene expression assay that stratifies intermediate-risk Oncotype DX patients into high- or low-risk for disease recurrence.”[1]. The study was performed by re-analyzing breast cancer tissue from 246 Weill Cornell patients whose tissue had previously been analyzed with Oncotype DX® by Genomic Health® (CA) . Gene expression analysis and BreastPRS calculations were performed in Signal Genetics’ CLIA-certified laboratory in Little Rock, AR.

The correlation between recurrence score and risk groups generated from the Oncotype DX and BreastPRS methods was highly statistically significant (P < 0.0001). Notably BreastPRS was found to reclassify Oncotype DX intermediate-risk patients into two groups with significant differences in recurrence free survival, potentially offering physicians an alternative method of breast cancer prognostication, which includes molecular grade and molecular subtyping algorithms to provide a comprehensive personalized analysis of each patient’s disease.

BreastPRS has also been used by researchers at the Windber Research Institute (Wind
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related biology technology :

1. Needle beam could eliminate signal loss in on-chip optics
2. Physicists skirt thermal vibration, transfer optical signal via mechanical oscillator
3. Laser-like photons signal major step towards quantum Internet
4. Researchers identify signals that direct the immune system to reject a transplanted organ
5. Signal-Health Develops Easy Checklist to Identify Possible Sweating Issues in Horses
6. Signal Genetics LLC Announces Update to MyPRS™ Gene Expression Profiling Assay for Multiple Myeloma
7. Interleukin Genetics Reports Third Quarter 2011 Financial Results
8. Metamark Genetics Signs Collaboration Agreement on Novel Therapeutic Targets with Janssen Biotech
9. Ambry Genetics Launches Illumina MiSeq Next-Gen Sequencing Services
10. Cytogenetics - Technologies, Markets and Companies
11. deCODE Genetics, in Collaboration with Academic Colleagues, Discovers Three Variants in the Sequence of the Human Genome that Affect the Risk of Thyroid Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/26/2015)... ... August 26, 2015 , ... The 2015 Epigenomics & Metabolomics Meeting ... company Asymmetrex to share the first report on progress with its crowdsourcing ... counting adult tissue stem cells. , With a name like “H2A.Z asymmetry,” the new ...
(Date:8/25/2015)... ... August 25, 2015 , ... A ... are cancerous is described by University of Illinois researchers in the Journal ... photonics. , In “ Breast cancer diagnosis using spatial light interference microscopy ,” ...
(Date:8/25/2015)... , Aug. 25, 2015 Human Longevity, Inc. (HLI), ... Winham has joined the company as Chief Operating Officer. ... medical operations and technical experience, will report directly to HLI,s ... In this new role as COO, Winham will be responsible ... as well as all facility operations. HLI currently has three ...
(Date:8/25/2015)... ... August 25, 2015 , ... ... and rackmount computing infrastructure, today announced the launch of its next generation, ... latest system boasts two distinct, individually sledded workstation nodes in each 1U ...
Breaking Biology Technology:Asymmetrex Reports Positive Indicators for Crowdsourcing Campaign to Evaluate New Biomarker for Counting Adult Tissue Stem Cells for the First Time 2Asymmetrex Reports Positive Indicators for Crowdsourcing Campaign to Evaluate New Biomarker for Counting Adult Tissue Stem Cells for the First Time 3Asymmetrex Reports Positive Indicators for Crowdsourcing Campaign to Evaluate New Biomarker for Counting Adult Tissue Stem Cells for the First Time 4New Optical Method Promises Faster, More Accurate Diagnosis of Breast Cancer 2New Optical Method Promises Faster, More Accurate Diagnosis of Breast Cancer 3New Optical Method Promises Faster, More Accurate Diagnosis of Breast Cancer 4Human Longevity, Inc. Hires Life Sciences Leader, Mark Winham, as Chief Operating Officer 2Cirrascale® Announces Next Generation High Density, Two-in-One GPU Rackmount Offering Perfect for High Performance Remote Workstations 2Cirrascale® Announces Next Generation High Density, Two-in-One GPU Rackmount Offering Perfect for High Performance Remote Workstations 3
... Thermo Fisher,Scientific Inc. (NYSE: TMO ), the world ... the 2008 Merrill Lynch Global Pharmaceutical,Biotechnology & Medical Device ... York City. The company will present on Thursday, February ... president and chief executive officer of Thermo,Fisher Scientific, will ...
... BD (Becton,Dickinson and Company) (NYSE: BDX ) announced ... today, elected Basil L. Anderson,Marshall O. Larsen, Gary A. ... of Directors. The BD Board currently consists of 13 ... Edward J. Ludwig,Chairman, President and Chief Executive Officer., ...
... SANTA CRUZ, Calif., Jan. 29 Expanding ... career resources to post-graduate and,alumni candidates, Bio Career ... joined forces., On Jan. 28, Emory University, ... Bio Career Center family, rounding out an,already elite ...
Cached Biology Technology:Thermo Fisher Scientific to Present at the 2008 Merrill Lynch Global Pharmaceutical, Biotechnology & Medical Device Conference 2BD Announces Results of Shareholder Votes at Annual Meeting 2Online Career Site for Life Science Professionals Continues Growth 2
(Date:8/4/2015)... 04, 2015 ... announced the addition of the "Digital ... Service), Sub-Segment (Computer Forensics, Network Forensics, Mobile ... Service, Vertical and Region - Global Forecast ... By Component (Hardware, Software, and ...
(Date:8/3/2015)... 2015 Synaptics, Inc. (Nasdaq: SYNA ), ... that members of the executive management team will present ... Technology Leadership Forum on Tuesday, August 11, 2015 at ... at the Sonnenalp Resort in Vail, CO. ... forward-looking information. An audio webcast of the event will ...
(Date:7/31/2015)... 2015 BGI llevará a cabo la 10ª Conferencia ... 25 de octubre de 2015, en Shenzhen, ... décimo aniversario este año. Desde su inauguración en 2006, ... anuales más influyentes del mundo en los campos de ... más dinámicas, entusiastas y amenas. ICG-10 se ...
Breaking Biology News(10 mins):Digital Forensics Market - The Market Represents a Compound Annual Growth Rate (CAGR) of 11.3% From 2015 to 2020 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 2La 10ª Conferencia Internacional sobre Genómica (ICG-10) comienza en octubre 3
... it survives on a diet of roundworm. But ... associate professor of biomedical engineering at the University of Tennessee, ... fighter. Zhang and his team have discovered that ... stimulating the immune system and killing tumors. The findings are ...
... NEW YORK, Dec. 4, 2012 A recent ABC News ... systems—to help ensure greater security in large childcare facilities. While ... stave off unwanted visitors and protect children from exiting the ... those who come in and out of the building. Slava ...
... of Seville (Spain) have developed a technique for estimating grape ... forward an index for identifying the ripeness of seeds without ... to decide the best moment for picking. The normal ... analysis. But this is a long and tedious task that ...
Cached Biology News:University of Tennessee researchers find fungus has cancer-fighting power 2Slava Volman Responds to Use of Biometrics for Security in Childcare Facilities 2A digital portrait for grapes indicates their ripeness 2
... (RNA polymers) are prepared ... of the enzyme, polynucleotide ... and the appropriate, ribonucleoside ... the exception of catalog ...
... Heavy duty stainless-steel shaker flask clips, ... high speeds. All clips are equipped ... (over 1L.) also include a bottom retainer ... prevent scratching of expensive glassware. Clips ...
RABBIT ANTI HUMAN ALPHA-2-ANTIPLASMIN...
... Bullseye Red Taq DNA Polymerase ... exhibits very high activity in primer extension ... contains a red dye which provides easy ... enzyme was added and allows confirmation of ...
Biology Products: