Sigma-Aldrich and Sangamo BioSciences Announce the Achievement of Key Throughput Milestone in Research Reagents...(every cell bind to DNA to regulate gene ...)

Date:1/12/2009

every cell, bind to DNA to regulate gene expression. Though there are many kinds of transcription factors, only ZFPs are amenable to engineering and precise targeting to a particular gene, or genes, of interest. By engineering ZFPs that recognize a specific DNA sequence, Sangamo scientists have enabled researchers to precisely modify targeted genes and control gene expression. This technology has the potential to play a major role in bringing new discoveries in genomics to the marketplace.

"Our ZFN technology is the gold standard for genome editing in cells and whole organisms," said Edward Lanphier, Sangamo's President and CEO. "There is a growing appreciation of the numerous applications of ZFP-based reagents in functional genomics, target validation, drug discovery, process improvement in biopharmaceutical manufacturing and the generation of transgenic animals. We are delighted with the progress that has been made in our collaboration with Sigma-Aldrich. Familiarity and success with our technology at the research level should lead to commercial success in this field as well as an appreciation of the broad therapeutic uses of our technology platform."

Sigma-Aldrich's agreement with Sangamo Biosciences, initiated in July 2007, provides Sigma-Aldrich with the exclusive right to utilize Sangamo's ZFP technology to develop and commercialize products for use as research reagents and to offer services in the research field. Sigma-Aldrich's CompoZr gene-editing technology was recently recognized as one of the Top 10 Innovations of 2008 by The Scientist and was included in the magazine's inaugural list of the most outstanding products to enter the life sciences market. For more information on Sigma-Aldrich's CompoZr ZFN technology platform, visit http://www.compozrzfn.com or contact a sales representative at '/>"/>

SOURCE Sangamo BioSciences, Inc. Copyright©2009 PR Newswire. All rights reserved

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