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Sigma-Aldrich and Oxford BioMedica Win Key Ruling in Open Biosystems Patent Infringement Dispute
Date:10/25/2007

with this Order, which validates Oxford BioMedica's patents and strengthens our position in this field." Oxford BioMedica's LentiVector system has broad applications in gene delivery and can be used to deliver shRNA-encoding DNA to cells to enable RNA Interference (RNAi) experiments. Based on discoveries by Oxford Biomedica's Drs. Susan and Alan Kingsman and others, scientists are now able to safely use modified lentiviruses as vectors, which enable RNAi to be effectively utilized as a research tool to unlock the secrets of the genetic code. As stated in the Court's Order, the viral vector developed by the Kingsmans' is expected to be useful as a "smart bomb" to safely "deliver new genetic material into specific cells, such as cells that do not divide or that divide slowly," giving the delivery of genes that produce dopamine into a Parkinson's disease patient's brain cells, as an example.

"Sigma believes this technology holds huge promise to better understand the human genome and to, ultimately, help devise techniques to defeat and diminish longstanding misery-causing diseases such as Parkinson's and Alzheimer's," said Smoller.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 36 countries and has 7,800 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at '/>"/>

SOURCE Sigma-Aldrich
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