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Sigma-Aldrich Signs Exclusive Agreement With IsoSciences, LLC, to Distribute Isotopically Labeled Bioactive Compounds
Date:9/11/2008

ST. LOUIS, Sept. 11 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) announced today that it has entered into an exclusive agreement with IsoSciences, LLC, to distribute isotopically labeled bioactive compounds and their metabolites (http://www.sigma-aldrich.com/isotope) through its Aldrich division. IsoSciences, a leading stable isotope company, provides a wide array of biological compounds and custom synthesis products. Aldrich, provider of ISOTEC(R) Stable Isotopes, is a leader in manufacturing and providing stable isotope products for biomolecular NMR, proteomics, metabolic and MRI research.

Under the terms of the agreement, IsoSciences will be the exclusive provider to Aldrich for their stable isotope products listed in the agreement. These products include deuterated, 13C and 15N labeled vitamins, steroids, and other bioactive compounds used in metabolic research.

Nutrition and metabolic research investigates the relationships among diet, health and diseases by nutrient interactions with various metabolic pathways, bioavailability and nutrient analysis. These stable isotope products will be an addition to the extensive list of unlabeled bioactive compounds provided by Sigma-Aldrich.

"A new partnership with IsoSciences will allow Sigma-Aldrich to provide new stable isotope product lines to support our customers' research," said Dr. C.T. Tan, ISOTEC Stable Isotope's R&D Manager. "This collaboration offers a new range of labeled bioactive compounds for our ever expanding customer base."

"We have invested heavily in synthesizing difficult-to-prepare, yet vitally needed, isotopically labeled standards," said David Saunders, President of IsoSciences, LLC.

IsoSciences' CEO Dr. Scott W. Landvatter added, "Our partnership with Sigma-Aldrich will allow us the widest possible distribution of our unique stable isotope labeled compounds to scientists worldwide."
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