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Sigma-Aldrich Introduces MISSION(R) LentiPlex(TM) Pooled shRNA Libraries to Enable Rapid Whole Genome Screening in Primary Cells, Stem Cells or Tumor Cells
Date:3/3/2009

y differentiated cells that are typically resistant to standard siRNA transfection or other viral delivery systems. In addition, Sigma-Aldrich's shRNA libraries include a U6 promoter for shRNA expression in a wide variety of cell lines including embryonic stem cells. These characteristics mean researchers can now conduct high quality pooled shRNA screens in the cell lines of their choice.

The MISSION LentiPlex Pooled shRNA Libraries add to Sigma-Aldrich's suite of MISSION shRNA products, which include the MISSION TRC-1 shRNA human (MISSION TRC-Hs1.0) and murine (MISSION TRC-Mm1.0) collections of whole genome arrayed libraries, gene family sets or individually prepared clones in glycerol, purified DNA or lentiviral formats. For more information on the MISSION LentiPlex Pooled shRNA Library, please visit http://www.sigma-aldrich.com/lentiplex.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Its biochemical and organic chemical products and kits are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development and as key components in pharmaceutical, diagnostic and other high technology manufacturing. The Company has customers in life science companies, university and government institutions, hospitals, and in industry. Over one million scientists and technologists use its products. Sigma-Aldrich operates in 37 countries and has 7,900 employees providing excellent service worldwide. Sigma-Aldrich is committed to Accelerating Customer Success through Innovation and Leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its award-winning Web site at http://www.sigma-aldrich.com.

Sigma-Aldrich, MISSION and LentiPlex are registered tr
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