Navigation Links
Sigma-Aldrich Introduces MISSION(R) In VIVO QUALITY and iScale Oligos(TM) siRNA, a Superior Quality siRNA Designed for RNAi Research in Animal Models
Date:11/20/2008

ST. LOUIS, Nov. 20 /PRNewswire-FirstCall/ -- Sigma-Aldrich (Nasdaq: SIAL) announced today the global release of MISSION(R) In VIVO QUALITY and iScale Oligos(TM) siRNA. MISSION(R) In VIVO QUALITY and iScale Oligos(TM) siRNA are expected to allow researchers to successfully take the next step in their RNAi research with the highest purity and quality siRNA required for RNAi research in animal models. These siRNA are believed to be well suited to target validation and pre-clinical siRNA testing. Intermediate and large synthesis scales and a wide variety of modifications are also available.

"Increasingly, RNAi researchers are utilizing animal models to confirm findings from cell culture based assays or to explore the use of siRNA as a potential therapeutic agent," said Tim Fleming, Director of Global Commercial Marketing at Sigma-Aldrich. "Our goal is to provide an siRNA that is capable of facilitating in vivo siRNA research, with the purity levels required for direct delivery or to be used as an essential part of an overall in vivo formulation strategy."

MISSION(R) In VIVO QUALITY siRNA are processed specifically for in vivo usage. This purification process includes RP-HPLC to ensure a high percentage of full-length product (>94%), dialysis on the annealed product to remove excess salts, 22 micrometer sterile filtration, and finally testing to ensure no endotoxins are present.

In addition, iScale Oligos(TM) synthesis scales can give customers the large quantities of siRNA required for in vivo usage with amounts up to 100mg. MISSION(R) In VIVO QUALITY and iScale Oligos(TM) siRNA are available with many of the common modifications used to for tracking or stability, such as FAM, Cy5(TM), and Cy3(TM).

"Sigma-Aldrich's MISSION(R) In VIVO QUALITY siRNAs are used exclusively at BIOO Scientific(TM) f
'/>"/>

SOURCE Sigma-Aldrich
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Sigma-Aldrich (Nasdaq: SIAL) Declares Quarterly Dividend
2. Sigma-Aldrich Introduces Methylated DNA Quantification Technology for Epigenetic Research
3. Sigma-Aldrich Releases WTA2, a Transplex Whole Transcriptome Amplification Technology for Degraded RNA Samples
4. Sigma-Aldrich (Nasdaq: SIAL) Reports 18.5% Gain in Q3 2008 Diluted EPS and Reaffirms Full Year 2008 Diluted EPS Forecast. Q3 2008 Sales Increase 7.4%. Buyback Authorization Increased by 10 Million Shares.
5. Sigma-Aldrich Welcomes Memorial Sloan-Kettering Cancer Center to the RNAi Partnership Program
6. Sigma-Aldrich and the University of Illinois Offer New Boronic Acid Surrogates to Researchers Worldwide Through Licensing Agreement
7. Sigma-Aldrich(R) Becomes First Life Science Company to Publish in Peer-Reviewed Video Journal JoVE
8. Sigma-Aldrich(R) Becomes First Life Science Company to Publish in PubMeds Peer-Reviewed Video Journal JoVE
9. Sigma-Aldrich to Present at the UBS 2008 Global Life Sciences Conference on September 24, 2008
10. Sigma-Aldrich Launches Breakthrough Genome-Editing Tools
11. Sigma-Aldrich Signs Exclusive Agreement With IsoSciences, LLC, to Distribute Isotopically Labeled Bioactive Compounds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... to settle into equilibriuma state of unchanging balance ... of non-equilibrium conditions where new possibilities lie. Non-equilibrium ... such as temperature fluctuations, freezing and melting, or ... body temperature, airplanes to fly, and the Earth ... even though these conditions exist naturally and are ...
(Date:7/24/2014)... Research and Markets has announced ... Analytical Instruments Market 2014-2018" report to their offering. ... Genomics is the study of the gene and its ... and functions of proteomes or sets of proteins by ... involves the mapping of genes and DNA sequencing to ...
(Date:7/24/2014)... 24, 2014 SRI International has been awarded ... Institute of Allergy and Infectious Diseases (NIAID), part of ... of potential therapies for HIV infection and AIDS. The ... and AIDS and the complications and opportunistic infections associated ... sexual transmission of HIV. According to ...
(Date:7/24/2014)... CA (PRWEB) July 24, 2014 Three ... be semi-finalists in Livestrong’s Big C Competition. Out of ... are each headed to the semi-final round. In this ... exclusive three-month accelerator program, complete with mentoring from thought-leaders ... , As part of the angelMD commitment to the ...
Breaking Biology Technology:New approach to form non-equilibrium structures 2Global Genomics and Proteomics Analytical Instruments Market 2014-2018: Key Vendors are Agilent, Bio-Rad , F. Hoffmann, La Roche, Illumina, PerkinElmer and Thermo Fisher Scientific 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 2National Institute of Allergy and Infectious Diseases Awards SRI International Contract to Study New Therapies for HIV and AIDS 33 angelMD Startups Make Livestrong Big C Semi-finals 2
... GENR ) today announced its financial results for ... net loss for,the three-month period ended September 30, 2007, ... as compared to a net loss of $4.5,million, or ... period,ended September 30, 2006. The net loss for the ...
... 9 Iomai Corporation,(Nasdaq: IOMI ) today announced ... the markets open and hold a conference call and,live ... Nov.,13, 2007 at 11 a.m. Eastern Time. Conference ... on Tuesday, Nov. 13 at 11 a.m.,Eastern Time via ...
... announced that it will conduct a,conference call and audio web cast on Tuesday, ... of its financial,results for the third quarter ended September 30, 2007. Lev anticipates,releasing ... November ... 1PM ET DIAL IN #: ...
Cached Biology Technology:Genaera Corporation Announces Third Quarter Financial Results 2Genaera Corporation Announces Third Quarter Financial Results 3Genaera Corporation Announces Third Quarter Financial Results 4Genaera Corporation Announces Third Quarter Financial Results 5Iomai to Announce Third Quarter 2007 Financial Results and Host Webcast on Tuesday, November 13 2Lev Pharmaceuticals Invites You to Participate in its Q3'07 Earnings Results Conference Call and Webcast 2
(Date:7/24/2014)... on average over a 35 year period in which ... impact of humans on declining animal numbers. This decline ... insects, spiders, crustaceans, slugs and worms bring to our ... decomposition for nutrient cycling, water filtration and human health. ... led by UCL, Stanford and UCSB, focused on the ...
(Date:7/24/2014)... A new study has identified two factors that ... increase the production of highly qualified physics teachers. ... to champion physics teacher education in combination with ... initiatives remain viable. Science, Technology, Engineering and Math ... and the study points the way for institutions ...
(Date:7/24/2014)... biodiversity, the product of 3.5 billion years of evolutionary ... of life. But it may be reaching a tipping ... and analysis of data published in Science , ... and decline of animals is contributing to what appears ... mass biological extinction event. , Since 1500, more than ...
Breaking Biology News(10 mins):Invertebrate numbers nearly halve as human population doubles 2Invertebrate numbers nearly halve as human population doubles 3Creating sustainable STEM teacher preparation programs 2Stanford biologist warns of early stages of Earth's 6th mass extinction event 2Stanford biologist warns of early stages of Earth's 6th mass extinction event 3
... German . The fingers on the outside ... than the middle finger, which is exposed to the "cross fire" ... handicap can be compensated. The working group led by PD Dr. ... report in the current issue of PNAS. Thumb and ...
... you really eating when you,re eating chicken? Do different types ... have similar fingerprints? How does sleep affect your memory? Does ... 33 local schools will answer these and other intriguing questions ... University of California, Riverside, Feb. 7-9. The fair will take ...
... of all took a long time to kill 90 percent ... newly published report. It shows that mass extinctions need ... the University of Cincinnati, and 13 colleagues have produced a ... on Ellesmere Island in the Canadian Arctic. Their analysis, ...
Cached Biology News:Why the middle finger has such a slow connection 2Why the middle finger has such a slow connection 3Fair to bring future scientists and engineers to UC Riverside 2Global extinction: Gradual doom as bad as abrupt 2Global extinction: Gradual doom as bad as abrupt 3
... for interferons are cytopathic effect inhibition assays, ... The neutralization assay measures the antibody's ... the cytokine. Sample types include; tissue culture ... these assays, one unit is defined as ...
... Yeast nitrogen base (YNB) is a base medium ... media. YNB contains ammonium sulfate but does not ... pouches are available. Each pouch contains reagents ... Pichia media or 1000 ml of 10X YNB ...
... ALDEFLUOR Stem Cell Identification ... comprises a substrate for ... (ALDH) that is highly ... stem cells, making ALDH ...
... MetaVue Imaging System is the cost-effective solution ... commands tailored to common research imaging tasks, ... analysis and simple image analysis. Compatibility ... library means that MetaVue has the power ...
Biology Products: